A5038782607- Respiratory viral infections research
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Trauma and Emergency Care Studies
- Healthcare Policy and Management
- Mathematical functions and polynomials
- Central Venous Catheters and Hemodialysis
- Metabolism and Genetic Disorders
- Cardiovascular Syncope and Autonomic Disorders
- Intensive Care Unit Cognitive Disorders
- Renal function and acid-base balance
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Mathematical Identities
- Asthma and respiratory diseases
- Antibiotic Use and Resistance
- Infant Development and Preterm Care
- Renal Transplantation Outcomes and Treatments
- Family and Patient Care in Intensive Care Units
- Adolescent and Pediatric Healthcare
- Renal Diseases and Glomerulopathies
Akron Children's Hospital
2023-2025
Northeast Ohio Medical University
2023-2025
Université de Montréal
2022-2024
Society of Critical Care Medicine
2022
Children's Hospital of Pittsburgh
2019-2022
University of Pittsburgh
2020-2022
University of Pittsburgh Medical Center
2021-2022
Charité - Universitätsmedizin Berlin
2022
University of Birmingham
2020-2021
NIHR Birmingham Biomedical Research Centre
2021
<h3>Importance</h3> In early 2020, the United States declared a public health emergency in response to coronavirus disease 2019 (COVID-19) and implemented variety of social distancing measures. The association between COVID-19 pandemic number pediatric admissions is unclear. <h3>Objective</h3> To determine changes patterns 2020 compared with prior decade. <h3>Design, Setting, Participants</h3> This cross-sectional study included 49 US hospitals contributing Pediatric Health Information...
To determine the changes in ICU admissions, ventilatory support, length of stay, and cost for patients with bronchiolitis United States.
The COVID-19 pandemic has been associated with a transient decrease in bronchiolitis hospitalizations compared prepandemic patterns, but current effects remain unknown.To analyze changes patterns of admissions at US children's hospitals during the 2020-2023 seasons 2010-2019 seasons.This retrospective cross-sectional study used data from 41 Pediatric Health Information System database. Bronchiolitis winter-predominant seasonality, so were grouped according to season (from July through June)....
Importance Admissions to the pediatric intensive care unit (PICU) due bronchiolitis are increasing. Whether this increase is associated with changes in noninvasive respiratory support practices unknown. Objective To assess whether number of PICU admissions for between 2013 and 2022 was use high-flow nasal cannula (HFNC), ventilation (NIV), invasive mechanical (IMV) identify factors HFNC NIV success failure. Design, Setting, Participants This cross-sectional study examined encounter data from...
The 2021 American Academy of Pediatrics clinical practice guideline (CPG) for well-appearing febrile infants aims to promote evidence-based care, reduce variability, enhance care quality, and optimize cost. We aimed examine the trends in resource utilization cost associated with evaluation management aged 8 60 days before after CPG's publication. performed a retrospective cross-sectional study using Pediatric Health Information Systems Database, covering periods August 2019 July (pre-CPG)...
Consciousness assessment is an important component in the prehospital care of ill or injured children. Both Glasgow Coma Scale (GCS) and Alert, Verbal, Pain, Unresponsive (AVPU) scale are used for this purpose. We sought to identify cut points GCS correspond AVPU pediatric emergency medical services (EMS) encounters.
Pediatric out-of-hospital cardiac arrest (OHCA) impacts 15,000-25,000 children annually in the U.S. The objective of this study was to determine if specific Emergency Medical Services (EMS) agency factors such as pediatric volume and preparedness factors, including hours required training, emergency care coordinator (PECC), or informational resources are associated with improved quality adverse events for OHCA. We conducted a retrospective chart review EMS clinical records survey among 5...
There are regional disparities in pediatric traumatic brain injury (TBI) mortality across the United States, but factors underlying these differences unclear. We performed a retrospective cross-sectional analysis of Pediatric Health Information System database including inpatient hospital encounters for children less than 18 years old with primary diagnosis TBI between 2010-2019. Lower median family income was associated mortality. Encounters from zip-codes <$20,000 had 3.1% (29/950)...
Abstract Millions of people worldwide are exposed to arsenic (As), a toxicant which increases the risk various cancers, cardiovascular disease and several other health problems. Arsenic is potent endocrine disruptor, including estrogen receptor. It was recently shown that environmental estrogen‐receptor disruptors can affect signaling mast cells, important players in parasite defense, asthma allergy. Antigen (Ag) or allergen crosslinking IgE‐bound receptors on cells leads signaling,...
OBJECTIVES: Mechanical ventilation (MV) is pervasive among critically ill children. We sought to validate a computerized physiologic equation predict minute requirements in children and test its performance against clinician actions an silico trial. DESIGN: Retrospective, electronic medical record linkage, cohort study. SETTING: Quaternary PICU. PATIENTS: Patients undergoing invasive MV, serial arterial blood gas (ABG) analysis within 1–6 hours, pharmacologic neuromuscular blockade (NMB)....
BACKGROUND AND OBJECTIVES The authors of previous work have associated the Childhood Opportunity Index (COI) with increased hospitalizations for ambulatory care sensitive conditions (ACSC). burden this inequity on health system is unknown. We sought to understand resource expenditure in terms excess hospitalizations, hospital days, and cost. METHODS performed a retrospective cross-sectional study Pediatric Health Information Systems database, including inpatient between January 1, 2016...
During the coronavirus disease 2019 pandemic, many women physicians experienced increased caregiver responsibilities, potentially leading to worsened gender inequities.We surveyed faculty and trainees at a quaternary-care children's hospital regarding work environment, household obligations, academic productivity examine differential effects on by parenting status. We used descriptive statistics for demographics analyzed Likert-scale responses with χ2 or Fisher's exact tests. performed...
Allergic diseases such as asthma have been on the rise in recent decades. Environmental or occupational exposure to estrogenic synthetic chemicals is suspected be a contributing factor, and previous experimental studies indicated that estradiol some xenoestrogens increase allergic signaling responses, degranulation, immune cells. In current study, data showed estrogen mimetic 4-tert-octylphenol (4tOP) enhances immunoglobulin (Ig) E-mediated degranulation of mammalian mast cell line RBL-2H3...
A relationship between Pao2 and mortality has previously been observed in single-center studies. We performed a retrospective cohort study of the Pediatric Health Information System plus database including patients less than or equal to 21 years old admitted medical cardiac ICU who received invasive ventilation within 72 hours admission. trained validated multivariable logistic regression prediction model with very good discrimination (C-statistic, 0.86; 95% CI, 0.79-0.92; area under...