INTRODUCTION: In 1956, Africanized honeybees (AHB) migrated from Brazil to other regions of the Western Hemisphere, including South, Central, and North America, except for Canada. Despite being productive, they are highly aggressive cause fatal accidents. This study aimed evaluate patients at Clinical Hospital Botucatu Medical School (HC-FMB) propose treatment guidelines. METHODS: From 2005 2006, clinical laboratorial aspects 11 (7 male 4 female) anatomopathological one patient who had died...

OBJECTIVE: outline the profile of women living with human immunodeficiency virus/aids in interior cities São Paulo State, attempt to identify characteristics related individual, social and programmatic vulnerability analyze conditions which they discovered their serological status. METHOD: between October 2008 December 2010, a cross-sectional study was undertaken 184 attended at specialized service. The data were collected through an interview gynecological test, including collection samples...

HIV infection and the prolonged use of antiretroviral therapy (ART) contribute to persistent inflammation immune deregulation in people living with HIV/AIDS (PLWHA). Propolis is a bee product plenty biological properties, including immunomodulatory anti-inflammatory action. This work aimed evaluate possible changes immune/inflammatory response PLWHA under ART after propolis intake. Asymptomatic were double-blindly randomized into parallel groups receiving (500 mg/day, n = 20) for 3 months or...

Objective Nucleoside/nucleotide reverse transcriptase inhibitors, particularly tenofovir, can cause long-term side effects such as decreased bone mineral density and estimated glomerular filtration rate. A strategy to mitigate these is the simplification of antiretroviral therapy, which involves withdrawing one nucleoside/nucleotide inhibitors from therapeutic scheme. While clinical trials real-world studies have demonstrated that simplified therapy maintains undetectable viral loads, its...

Infection with human papilloma virus (HPV) is the most common sexually transmitted disease in world. Among 630 million new cases of HPV that occur each year, 30 develop anogenital warts. Although subclinical infection cause, genital warts are also associated immunosuppression caused by HIV. In view high prevalence HPV/HIV co-infection particularly among men who have sex men, objectives this study were to determine HIV/AIDS and identify factors.A cross-sectional was conducted on 159...

We studied the influence of weather on etiology healthcare-associated bloodstream infections in a hospital Brazil during years 2005-2010. Monthly average temperatures were positively associated with higher incidence gram-negative bacilli as whole, Acinetobacter baumannii, and Enterobacter species. The same groups presented seasonal behavior stochastic models.

Sustained adherence to antiretroviral therapy (ART) is critical in the prevention of drug resistance, disease progression, and death. We aimed assess level ART among 112 people living with HIV/AIDS (PLWHA) determine associated factors that. The socioeconomic aspects were evaluated by medical records; adherence, depression, coping specific questionnaires. Although most patients have undetectable viral load (79%) CD4+ T count >500 cells/mm3 (65%), two-third (66%) them exhibited a lower which...

Propolis is a natural product has many biological properties of clinical interest, such as anti-inflammatory and antioxidant. Considering that people living with HIV/aids (PLWHA) on effective combined antiretroviral therapy (cART) present early aging due to an intense immune activation, inflammation, redox imbalance, propolis consumption could offer benefit patients. This double-blind longitudinal study evaluated whether Brazilian green pills intake (500 mg/day for three months) would...

At present, few data are available on the prevalence and antifungal susceptibility of Candida parapsilosis complex isolates from HIV-infected individuals. The C. comprises three species, sensu stricto, metapsilosis orthopsilosis. Fifteen 318 were identified as members by PCR restriction fragment length polymorphism (RFLP). was 4.7 %, 2.2 % being stricto 2.5 metapsilosis, while no orthopsilosis isolated. This is believed to be first study that has obtained oral cavity Antifungal tests...

Background . The combination antiretroviral therapy (cART) increases the oxidative stress in HIV‐infected people, which turn favors onset and aggravation of non‐AIDS comorbidities, a common situation affecting these individuals. We aimed to evaluate influence cART initiation on parameters. This is longitudinal study including 30 asymptomatic patients divided according their CD4+ T cell count (G1: <500 cell/mL; G2: >500 cell/mL) before (M0) after (M1) initiation. analyzed total...

Diarrhea caused by Cryptosporidium sp is frequent in patients with AIDS, but involvement of other organs the digestive tract uncommon. We report a case Cryptosporidium-associated obstruction biliary mimicking cancer head pancreas 43-year-old woman AIDS.

Randomly amplified polymorphic DNA (RAPD) analysis of 35 Paracoccidioides brasiliensis isolates was carried out to evaluate the correlation RAPD profiles with virulence degree or type clinical manifestations human paracoccidioidomycosis. The dendrogram presented two main groups sharing 64% genetic similarity. Group A included from patients chronic paracoccidioidomycosis; group B comprised following showing 65% similarity: non-virulent, six attenuated, five virulent, eight...

Aims: To report the first eight bone marrow necrosis (BMN) cases related to paracoccidioidomycosis (PCM) from patient autopsies with well‐documented (BM) histology and cytology. Methods results: A retrospective evaluation was performed on BM specimens autopsied patients Botucatu University Hospital PCM‐related BMN. Relevant BMN literature searched analysed. Conclusions: All had acute PCM. Six histological only (biopsies) two cytological (smears) specimens. Five biopsy revealed severe one...

OBJECTIVE To evaluate if temperature and humidity influenced the etiology of bloodstream infections in a hospital from 2005 to 2010. METHODS The study had case-referent design. Individual cases caused by specific groups or pathogens were compared with several references. In first analysis, average values for seven days preceding collection blood cultures an overall "seven-days moving average" period. second analysis included only patients infections. Several logistic regression models used...

Antiretroviral resistance mutations (ARM) are one of the major obstacles for pharmacological human immunodeficiency virus (HIV) suppression. Plasma HIV-1 RNA from 306 patients on antiretroviral therapy with virological failure was analyzed, most them (60%) exposed to three or more regimens, and 28% have started before 1997. The common regimens in use at time genotype testing were AZT/3TC/nelfinavir, 3TC/D4T/nelfinavir AZT/3TC/efavirenz. majority ARM occurred protease (PR) gene residue L90...

The development of the typical comorbidities aging which currently affects people living with HIV/AIDS (PLWHA) can be partially ascribed to persistent immune activation and chronic inflammation characterizing these individuals. aim this study was analyze effect exerted by combined antiretroviral therapy (cART) administration on plasma levels HMGB1 (high mobility group box protein-1), AGEs (advanced glycation end products), their soluble receptor sRAGE, cytokines, C-reactive protein (CRP),...

ABSTRACT Patients infected with the human immunodeficiency virus (HIV) are at higher risk of developing Epstein–Barr Virus (EBV)‐associated lymphomas. The usefulness monitoring EBV in peripheral blood mononuclear cells (PBMCs) patients HIV has not been established. aim this study was to evaluate viral load PBMCs, frequency genotypes, and presence 30‐bp deletion BNLF‐1 gene. DNA samples from 156 attending HIV/AIDS Day Clinic Botucatu School Medicine, Sao Paulo State University were evaluated....

"HIV / AIDS - Quality of Life” (HAT-Qol) is an instrument used to measure the quality life HIV-infected individuals. The study examined individuals with HIV infection, related socio-demographic and clinical data. Data collection was performed by retrospective analysis medical records 450 patients registered, then HAT-Qol. Met inclusion criteria, 169 patients. showed that There influence age in relation Domain which assesses satisfaction sexual activity marital status awareness about HIV....

AIDS is a disease caused by HIV that compromises the organism's immune system. The advent of highly active antiretroviral therapy (HAART) has promoted substantial improvement in prognosis for this and HIV/AIDS patients' quality life. During prolonged treatment, certain hematological disorders are observed, such as anemia macrocytosis, well deficiencies micronutrient vitamin B12 folic acid. objective study was to correlate presence macrocytosis with HAART use or acid deficiencies.110...

SUMMARY Combination Antiretroviral Therapy (cART) aims to inhibit viral replication, delay immunodeficiency progression and improve survival in AIDS patients. The objective of this study was compare two different schemes cART, based on plasma load (VL) CD4+ T lymphocyte count, during 48 weeks treatment. For purpose, 472 medical charts a Specialized Outpatient Service were reviewed from 1998 2005. Out these, 58 patients who had received triple drug scheme as the initial treatment included...