Juliane Gehrke
A5052038745- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Health and Medical Studies
- Medical and Health Sciences Research
- Chronic Disease Management Strategies
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
University Hospital of Basel
2021-2022
University of Basel
2021-2022
Deutsches Forschungsnetz
2021
Collaboration for the Diagnosis and Evaluation of Acute Coronary Syndrome (CoDE-ACS) is a validated clinical decision support tool that uses machine learning with or without serial cardiac troponin measurements at flexible time point to calculate probability myocardial infarction (MI). How CoDE-ACS performs different points measurement compares guideline-recommended diagnostic pathways rely on fixed thresholds uncertain.
Background: The non–ST-segment–elevation myocardial infarction (NSTEMI) guidelines of the European Society Cardiology (ESC) recommend a 3h cardiac troponin determination in patients triaged to observe-zone ESC 0/1h-algorithm; however, no specific cutoff for further triage is endorsed. Recently, 0/3h high-sensitivity T (hs-cTnT) change (7 ng/L) was proposed, warranting external validation. Methods: Patients presenting with acute chest discomfort emergency department were prospectively...
Rapid and accurate noninvasive discrimination of type 2 myocardial infarction (T2MI), which is because a supply-demand mismatch, from 1 (T1MI), arises via plaque rupture, essential, treatment differs substantially. Unfortunately, this major unmet clinical need, even high-sensitivity cardiac troponin (hs-cTn) measurement provides only modest accuracy.
Abstract Aims Cardiac myosin-binding protein C (cMyC) demonstrated high diagnostic accuracy for the early detection of non-ST-elevation myocardial infarction (NSTEMI). Its dynamic release kinetics may enable a 0/1h-decision algorithm that is even more effective than ESC hs-cTnT/I 0/1 h rule-in/rule-out algorithm. Methods and results In prospective international study enrolling patients presenting with suspected NSTEMI to emergency department, cMyC was measured at presentation after 1 in...
Abstract Aims After rule-out of non-ST elevation myocardial infarction (NSTEMI) with the European Society Cardiology (ESC) 0/1 h-algorithms, it is unclear which patients require further anatomical or functional cardiac testing. To test safety and efficacy no-objective-testing (NOT)-rules after NSTEMI by ESC h-algorithms. Methods results International, prospective, diagnostic multicentre study enrolling adult presenting chest pain to emergency department. Central adjudication final diagnosis...
doch erfullen Studienprotokolle, eingesetzte Erhebungsinstrumente und erhobene Daten die Anforderungen der FAIR-Prinzipien nicht in ausreichendem Mase. NFDI4Health wird daher eine Struktur schaffen, zentrale Suche nach existierenden, dezentral verwalteten Datenkorpern zugehorigen Dokumenten sowie einen FAIRen Zugang zu diesen erleichtert. Dazu werden Auffindbarkeit strukturierten Gesundheitsdaten aus Registern, administrativen Gesundheitsdatenbanken, klinischen epidemiologischen Public...