A5041957172- Algal biology and biofuel production
- Photosynthetic Processes and Mechanisms
- Microbial Community Ecology and Physiology
- Microbial Metabolic Engineering and Bioproduction
- Aquatic Ecosystems and Phytoplankton Dynamics
- Biocrusts and Microbial Ecology
- Genomics and Chromatin Dynamics
- Liver Disease Diagnosis and Treatment
- Nitric Oxide and Endothelin Effects
- Mitochondrial Function and Pathology
- Cardiovascular Function and Risk Factors
- Electron Spin Resonance Studies
- Protist diversity and phylogeny
- Gestational Diabetes Research and Management
- RNA Research and Splicing
- Catalysis for Biomass Conversion
- Gut microbiota and health
- Ovarian function and disorders
- Retinal Imaging and Analysis
- Genomics and Phylogenetic Studies
- Retinal Diseases and Treatments
- RNA and protein synthesis mechanisms
- Endoplasmic Reticulum Stress and Disease
- Catalysis and Hydrodesulfurization Studies
- interferon and immune responses
South Dakota State University
2016-2025
Shanghai First People's Hospital
2012-2025
Shanghai Jiao Tong University
2015-2025
University of Shanghai for Science and Technology
2025
University of Electronic Science and Technology of China
2024
China Electric Power Research Institute
2023
North China Electric Power University
2023
Shanghai Sixth People's Hospital
2015-2022
Punan Hospital
2021
Zhangjiagang First People's Hospital
2020
In the ever-evolving landscape of sustainable agriculture, cyanobacterium has emerged as a viable option to offer multifaceted benefits both crops and environment. This comprehensive review navigates contributions cyanobacteria in agriculture begins with an insightful exploration their fundamental role agricultural systems. article explains mechanisms through which may foster plant growth demonstrates ability boost crop yields optimize nutrient utilization. Their capacity alleviate stresses...
The symbiotic relationship between nitrogen-fixing cyanobacteria and plants offers a promising avenue for sustainable agricultural practices environmental remediation. This review paper explores the molecular interactions nanoparticles, shedding light on their potential synergies in nanotechnology. Delving into evolutionary history specialized adaptations of cyanobacteria, this highlights pivotal role fixing atmospheric nitrogen, which is crucial ecosystem productivity. discusses unique...
Abstract This review explores the potential of genetically engineering cyanobacteria with aim synthesizing high‐value protein directly from atmospheric nitrogen. The article examines numerous techniques that may enhance synthesis in cyanobacteria, and discusses advantages, barriers, opportunities for this strategy going forward. Genetic manipulation shows promise sustainably raising production via reduced greenhouse gas emissions lower dependence on synthetic fertilizers, but also...
Objective: The objective of this study was to test the association personality traits neuroticism and extraversion with risk death in old age. Methods: A census taken a geographically defined urban community Chicago, those aged 65 years or older were invited participate an in-home interview; 6158 (79% eligible) did so. interview included brief measures extraversion, medical history, questions about current participation cognitive, social, physical activities. Vital status subsequently...
Spexin mRNA and protein are widely expressed in rat tissues associate with weight loss rodents of diet-induced obesity. Its location endocrine epithelial cells has also been suggested. is a novel peptide that involves Therefore, we aimed to examine its expression human test whether spexin could have role glucose lipid metabolism type 2 diabetes mellitus (T2DM). The the gene immunoreactivity adrenal gland, skin, stomach, small intestine, liver, thyroid, pancreatic islets, visceral fat, lung,...
Engineering the filamentous, N<sub>2</sub>-fixing cyanobacteria as a cellular factory to produce and secrete cyclic hydrocarbon fuel using atmospheric gases (CO<sub>2</sub>and N<sub>2</sub>), water, sunlight.
Objective: Recent studies demonstrate circulating serum spexin levels are reduced in obesity or type 2 diabetes mellitus (T2DM) patients and may play a role glucose metabolism.The mechanism underlying is not known.In this study, we explore whether has insulin resistance hepatic metabolism.Methods: The correlation between the homeostasis model assessment of (HOMA-IR) was studied newly diagnosed T2DM patients.After intraperitoneal injection exogenous for 8 weeks, effect on infusion rates...
Diabetic retinopathy (DR) is the leading cause of blindness among working-age population. Although controlling blood glucose levels effectively reduces incidence and development DR to less than 50%, there are currently no diagnostic biomarkers or effective treatments for in glucose-well-controlled diabetic patients (GW-DR). In this study, we established a prospective GW-DR cohort by strictly adhering glycemic control guidelines maintaining regular retinal examinations over median 2-year...
The sophisticated, elegant protein-polymers designed by nature can serve as inspiration to redesign and biomanufacture protein-based materials using synthetic biology. Historically, petro-based polymeric have dominated industrial activities, consequently transforming our way of living. While this benefits humans, the fabrication disposal these causes environmental sustainability challenges. Fortunately, biopolymers compete with potentially surpass performance polymers because they be...
Obesity‐induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps adapt cellular involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against adipocytes. An vitro model was used which 3T3‐L1 were preloaded with palmitate (PA) generate artificial hypertrophy mature Elevated autophagy flux increased number autophagosomes observed response PA rapamycin treatment....
Objective Gut microbial dysbiosis is associated with high heterogeneity of polycystic ovary syndrome (PCOS); however, studies about gut microbiota targeted clinical intervention in PCOS are limited. Our study aimed to evaluate the effects high-fiber diet or combined acarbose on phenotypes PCOS, focusing possible influence this process. Methods Twenty-five patients were recruited and randomly divided into two groups, W group (n = 14) received WTP (a composed whole grains, traditional Chinese...
Abstract Cyanobacteria, which are photosynthetic prokaryotes, have gained attention in recent years for their potential health benefits. One notable property of cyanobacteria is high antioxidant capacity, has been attributed to various beneficial properties. Antioxidants crucial the human body as they help scavenge free radicals that can cause cellular damage and lead diseases. The fermentation food using other microorganisms a traditional practice centuries found enhance capacity food. This...
This comprehensive review investigates the potential of cyanobacteria, particularly nitrogen-fixing strains, in addressing global challenges pertaining to plastic pollution and carbon emissions. By analyzing distinctive characteristics including their minimal growth requirements, high photosynthetic efficiency, rapid rates, this study elucidates crucial role transforming sequestration, biofuel generation, biodegradable production. The investigation emphasizes cyanobacteria’s efficiency...
An Arabidopsis thaliana mutant was identified as having increases in 12 of 20 free proteogenic amino acids seeds. Because these metabolites are produced from multiple, seemingly unrelated biosynthetic networks, it not possible to use a candidate gene approach discover the enzyme defect responsible for this complex syndrome. Complementary metabolite profiling analyses revealed increased seed homomethionine and isovaleroyloxypropyl-glucosinolate, along with reduced...
A modified LC−MS/MS method for large-scale screening of metabolic phenotypes was developed and validated. Twenty amino acids 5 metabolically related compounds are measured within 4 min using multiple reaction monitoring (MRM) transitions selective each compound. Separation with a short C18 column rapid gradient the ion-pairing reagent perfluoroheptanoic acid allows chromatographic resolution isomers Ile Leu improved peak shapes Lys, Arg, His. MRM were established capability to distinguish...
Endoplasmic reticulum (ER) stress and inflammation induced by obesity lead to adipocyte dysfunction, with the impairment of insulin pathway. Recent studies have indicated that understanding physiological role autophagy is great significance. In present study, an in vitro model was used which 3T3-L1 adipocytes were pre-loaded palmitate (PA) generate artificially hypertrophied mature adipocytes. PA autophagic flux, determined increased microtubule-associated protein 1 light chain 3 (LC3)-II...
Abstract Objective This study aimed to explore the relationship of thyroid function and glucose metabolism investigate changes in after National Metabolic Management Center (MMC) management type 2 diabetic mellitus (T2DM). Methods A total 2000 euthyroid participants from MMC Shanghai General Hospital a community physical examination were recruited. They categorized into four groups: normal tolerance (NGT, n = 132), prediabetes (N 147), DM well‐controlled (T2DM with glycosylated hemoglobin...
Abstract Current artificial neuromorphic systems are mainly constructed using solid‐state optoelectronic synaptic devices, limiting their potential intelligence applications in liquid medium. Here, colloidal CuInGaSe/ZnSe quantum dots (QDs) with environment‐benign feature and broad visible light absorption prepared to fabricate a photoelectrochemical (PEC)‐type device operating aqueous electrolyte, enabling unique biological behaviors including paired‐pulse facilitation (PPF), short‐term...