A5073317379- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Infectious Diseases and Tuberculosis
- Surgical site infection prevention
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Antimicrobial agents and applications
- Knee injuries and reconstruction techniques
- Streptococcal Infections and Treatments
- Musculoskeletal Disorders and Rehabilitation
- Syphilis Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Reproductive tract infections research
- Nail Diseases and Treatments
- Rheumatoid Arthritis Research and Therapies
- Hematological disorders and diagnostics
- Mycobacterium research and diagnosis
- Orthopedic Surgery and Rehabilitation
- Spondyloarthritis Studies and Treatments
- Organ and Tissue Transplantation Research
- Infectious Diseases and Mycology
- Bone fractures and treatments
Hospital for Special Surgery
2012-2024
Cornell University
2011-2022
University of Southern California
2020
Clinical Orthopaedics and Related Research
2020
State Street (United States)
2020
Weill Cornell Medicine
2016-2017
College Medical Center
2016
NewYork–Presbyterian Hospital
2013
Faculty of 1000 (United States)
2005
University of Nebraska Medical Center
1994
The results of eleven two-stage reimplantations to salvage infected total knee arthroplasties in ten women (seven with osteoarthritis and three rheumatoid arthritis) were evaluated after an average follow-up thirty-four months. staged procedures included removal all the components prosthesis cement, then six weeks parenteral antibiotic therapy (monitored by maintaining serum bactericidal levels at a peak dilution 1:8), finally reimplantation condylar-type prosthesis. All antibiotics...
To determine the effect of ventilation system on infection rates after total hip and knee arthroplasties performed in operating rooms with without a horizontal unidirectional filtered air-flow system, using modern antiseptic conditions antibiotic prophylaxis, all single-stage procedures (3175 4769) were subjected to statistical analysis fifty-seven matched pairs for controls established. A reduced rate replacement (from 1.4 0.9 per cent) an increased 3.9 found when patients operated laminar...
Thirty-eight total knee replacements (in thirty-five patients) that were complicated by infection treated with a two-stage protocol for reimplantation. The clinical results in these knees (nine of which have been previously reported on) evaluated at an average follow-up four years (range, 2.5 to ten years). There was only one documented recurrence the original organism. Three patients whom immunological system suppressed had subsequent hematogenous different According knee-rating Hospital...
We performed a retrospective study of knee joint infections after arthroscopic anterior cruciate ligament reconstruction at our institution. Two thousand five hundred reconstructions were between 1988 and 1993. Seven (0.3%) patients experienced postoperative deep the knee. All using arthroscopically assisted techniques. Six (86%) these had concomitant open procedures performed, including meniscal repair, posterolateral corner reconstruction, medial collateral reconstruction. Four acute (< 2...
Background. The epidemiology, pathogenesis, clinical manifestations, management, and outcome of Candida osteomyelitis are not well understood. Methods. Cases from 1970 through 2011 were reviewed. Underlying conditions, microbiology, mechanisms infection, antifungal therapy, studied in 207 evaluable cases. Results. Median age was 30 years (range, ≤ 1 month to 88 years) with a >2:1 male:female ratio. Most patients (90%) neutropenic. Localizing pain, tenderness, and/or edema present 90%...
A prospective study was performed to evaluate the arthroplasty fluid, serum, and urine antibiotic levels in 38 patients implanted with gentamicin-impreg-nated cement 18 gentamicin-impregnated beads. Radioimmune assays were on samples at various times after surgery. On day 1, high fluid of gentamicin eluted from bead-implanted (mean, 36.9 μg/ml; range, 19.6–69.5) cement-implanted 14.9 2.7–38.9) very low serum levels. The obtained 1 17 higher, patients, seven than those intravenous...
SALVATI, EDUARDO A. M.D.; CHEKOFSKY, KENNETH M. BRAUSE, BARRY D. WILSON, PHILIP Jr. M.D.Editor(s): CRACCHIOLO, ANDREA III M.D. Author Information
Objective This collaboration between the American College of Rheumatology and Association Hip Knee Surgeons developed an evidence‐based guideline for perioperative management antirheumatic drug therapy adults with rheumatoid arthritis (RA), spondyloarthritis (SpA) including ankylosing spondylitis psoriatic arthritis, juvenile idiopathic (JIA), or systemic lupus erythematosus (SLE) undergoing elective total hip (THA) knee arthroplasty (TKA). Methods A panel rheumatologists, orthopedic...
Abstract Antibiotic‐loaded bone cement (ALBC) is broadly used to treat orthopaedic infections based on the rationale that high‐dose local delivery essential eradicate biofilm‐associated bacteria. However, ALBC formulations are empirically drug susceptibility from routine laboratory testing, which known have limited clinical relevance for biofilms. There also dosing concerns with nonstandardized, surgeon‐directed, hand‐mixed formulations, unknown release kinetics. On basis of our knowledge in...
Forty-four patients (46 hips) with infected total hip arthroplasties were evaluated. They entered into a protocol that included resection arthroplasty, six weeks of intravenous antibiotics which obtained minimum postpeak serum bactericidal titer 1:8, and possible reimplantation. Thirty-two 46 hips (70%) reimplanted. At an average 40 months (range, 24–74 months) after reimplantation, infection recurred in three (9%). In two the recurrent infections, 1% titers not attained. Both these...
Between 1983 and 1986, 40 hip arthroplasties in patients with documented deep infection were reimplanted using Palacos Gentamicin at The Hospital for Special Surgery. was added to the standard protocol, which included removal of prosthesis, cement, if present, a thorough debridement infected necrotic tissue, six weeks intravenous antibiotics postpeak serum bactericidal titer least 1:8 against infecting bacteria, followed by reimplantation hip. Sixteen also had placement...
From the Knee Service, The Hospital for Special Surgery, Affiliated with New York Hospital-Cornell University Medical College, City
A retrospective analysis was performed of 12 patients who required soft-tissue coverage an exposed or infected total knee prosthesis between 1982 and 1989. All knees had skin closure with medial gastrocnemius muscle flaps. At a mean follow-up period 41 months, all were treated for prostheses removal the implant, intravenous antibiotics, flap excellent clinical result complete no infection. Five six went on to successful reimplantation. Of prosthesis, five outcome retention prosthesis. Thus,...