- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Salmonella and Campylobacter epidemiology
- Streptococcal Infections and Treatments
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Fungal Infections and Studies
- Vaccine Coverage and Hesitancy
- Hepatitis B Virus Studies
- Urinary Bladder and Prostate Research
- Nail Diseases and Treatments
- Urinary Tract Infections Management
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Viral Infections and Vectors
- Antimicrobial agents and applications
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis C virus research
- Leptospirosis research and findings
- Orthopedic Infections and Treatments
All India Institute of Medical Sciences Rishikesh
2018-2025
Vardhman Mahavir Medical College & Safdarjung Hospital
2023-2025
Princess Royal University Hospital
2021-2025
King's College Hospital NHS Foundation Trust
2025
All India Institute of Medical Sciences, Deoghar
2023
King's College Hospital
2022
Galgotias University
2022
Heinrich Heine University Düsseldorf
2020
All India Institute of Medical Sciences Raipur
2020
All India Institute of Medical Sciences Bhopal
2020
Aim: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major public health concern, particularly in immunocompromised and critically ill patients. Colistin tigecycline are among the last-resort treatment options, while primary driver of CRKP emergence carbapenemase production, especially (KPC) metallo-β-lactamase (MBL). A thorough understanding its resistance mechanisms essential for selecting most effective antimicrobial therapy. This study aimed to evaluate diagnostic accuracy...
Introduction: Maternal infections caused by TORCH [Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), Herpes simplex virus (HSV)] and others agents like Chlamydia trachomatis,Treponema pallidum, Neisseria gonorrhoeae, HIV, etc. are the major causes of bad obstetric history(BOH). Aim study: To evaluate incidence in pregnancy wastage women with BOH. Methodology: The study included 87 pregnant history. Cases hypertension, diabetes mellitus, eclampsia pregnancy, Rh incompatibility were...
serovar Typhi and Paratyphi usually cause enteric fever in humans characterized by gastrointestinal symptoms such as diarrhea. Bacteremia is a constant feature of fever, occasionally, dissemination bacilli throughout the body results establishment one or more localized foci persisting infection. This happens especially patients with preexisting conditions hemoglobinopathies, previous joint trauma, surgery, connective tissue diseases, lymphoma, diabetes, alcoholism, immunosuppressive state,...
Context: Possible linkage between biocide and antibiotic resistance in bacteria is a major area of concern. Aim: To evaluate the susceptibility multidrug-resistant (MDR) to four commonly used biocides. Settings Design: A pilot study was conducted tertiary care hospital from April November 2017. Materials Methods: Fifty-four MDR bacterial isolates, namely Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, were obtained various clinical samples inpatients....
Abstract Context Febrile neutropenia is a serious complication of chemotherapy affecting patients with both hematological and solid malignancies, respectively. To the best our knowledge, there paucity literature from Uttarakhand, India on microbiological profile blood stream infections (BSIs) in febrile neutropenic patients. Aims The study aims to generate preliminary data antibiotic resistance pattern BSIs Settings Design design involved cross-sectional January 1, 2019 July 31, 2019....
Cultivated meat is a fast-growing research field and an industry with great potential to overcome the limitations of traditional production. utilizes cell culture tissue engineering technologies vast number cells in vitro grow/assemble them into structures mimicking muscle tissues livestock animals. Stem self-renewal lineage-specific differentiation abilities have been considered one key sources for cultivated meats. However, extensive culturing/expansion stem results reduction their...
Cultivated meat (clean meat) is an emerging yet fast growing research field and industry with a great potential to overcome the limitations of traditional cattle production. leverages technologies cell biology tissue engineering, culturing multiple types cells assembling them into structure construct mimicking muscle tissues livestock animals. A sustainable source first utmost important component cultivated technology. In this mini review, sources for main in (muscle fat cells) are...
Background: Epidemiological data regarding paediatric pyogenic musculoskeletal infections from developing countries of Asia and Africa are sparse is further complicated by presence factors like malnutrition, delay in initiating treatment, belief alternative form treatment under vaccination. The aim this study to retrospectively analyse the cases a tertiary care centre India. Methods: It retrospective including patients below 18 years age who had been diagnosed with any infection....
Urinary tract infection (UTI) in children is one of the commonest bacterial infections seen pediatric population. Clinical presentation ranges from fever with or without focus and isolation microbiological agents streamline treatment. Moreover, local/regional microbial profiles are helpful antibiotic selection, we conducted a study to assess prevalence urine culture positivity suspected case UTI. In addition, susceptibility patterns ultrasonography (USG) finding culture-positive patients...
Although existence of a probable association between glycopeptide and biocide resistance among enterococci has often been hypothesized, all studies conducted so far on this subject have inconclusive.The aim study was to explore the possibility an reduced susceptibility biocides Enterococcus spp.This pilot in super-speciality hospital situated New Delhi, India, June November, 2015.Fourteen isolates spp. obtained from various clinical samples inpatients were subjected testing by modified...
Dealing with carbapenem-resistant Klebsiella pneumoniae (CR-Kp) strains, which are generally pan-drug resistant, is an uphill task for health care professionals. Owing to limited therapeutic options and the possibility of development resistance commonly used biocides in hospital settings, CR-Kp infections pose a serious threat emergence dreaded pandemic. The aim study was highlight biocide among strains. A case conducted Super-specialty Hospital September 2015. 65-year-old female patient...
Introduction Acinetobacter species has become a leading cause of nosocomial infections in recent years. Objectives The aim the study was to establish usefulness matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) mass spectrometry (MS) for identification with respect conventional biochemical methods and MicroScan WalkAway 96 Plus system compare antibiotic susceptibility test results Kirby-Bauer disk diffusion method automated antimicrobial testing system. Materials Methods...
Context: As reports on colistin resistance are slowly emerging from different parts of the world, it is imperative that clinical microbiology laboratories should generate accurate in vitro susceptibility results. Aim: The aim to preliminary data diagnostic utility MicroScan WalkAway 96 Plus Identification ID/Antimicrobial testing AST system determining carbapenem-resistant Gram-negative bacterial isolates. Settings and Design: A pilot study was conducted a tertiary care teaching hospital...
Occult hepatitis B infection (OBI) may contribute to liver damage and variable therapeutic response in patients with chronic C (CHC) infection.To study the prevalence of OBI evaluate its impact and/or that anti-HBc total seropositivity on clinical outcomes directly acting antiviral (DAA) therapy CHC-infected patients.A retrospective cohort was conducted a tertiary care hospital from January May 2017.Eighty HBsAg-negative CHC who were initiated DAA retrospectively included. Archived...
To the best of our knowledge, there are no reports serological evidence human leptospirosis from Uttarakhand state in India.The aim this study was to screen for patients with acute undifferentiated febrile illness at a tertiary care teaching hospital Uttarakhand.A pilot conducted March November 2017.Fifty-three adult who presented Medicine outpatient Department history fever ≥7 up 14 days duration or without other associated symptoms such as headache, rashes, myalgia, arthralgia, and...
Implementation of quality management system (QMS) which encompasses various indicators (QIs), can serve as a stepping stone for continuous improvement & help in achieving globally accepted standards diagnostic laboratory.To generate preliminary data on trends post-analytical QIs Bacteriology section.A pilot study was conducted at tertiary care teaching hospital located Rishikesh, Uttarakhand.Data the following four pertaining to aerobic culture and sensitivity testing clinical samples...
To provide an insight into the Whole-genome sequencing (WGS) data of MRSA strains circulating in a teaching hospital north India.An exploratory study was conducted which fifty non-repetitive isolates obtained from pus samples inpatients July 2018 to February 2019 were subjected preliminary identification (ID) and antibiotic susceptibility testing (AST) at our centre. These later sent Central Research Laboratory, India for further using VITEK-2 compact system followed by WGS. Only eighteen...