A5010446297- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Shoulder and Clavicle Injuries
- Bone fractures and treatments
- Shoulder Injury and Treatment
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Bone health and osteoporosis research
- Knee injuries and reconstruction techniques
- Trauma Management and Diagnosis
- Adipokines, Inflammation, and Metabolic Diseases
- NF-κB Signaling Pathways
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Muscle and Compartmental Disorders
- Advanced materials and composites
- Vascular Malformations and Hemangiomas
- Nerve Injury and Rehabilitation
- Osteoarthritis Treatment and Mechanisms
- Nausea and vomiting management
- Advanced Sensor and Energy Harvesting Materials
- Intestinal and Peritoneal Adhesions
- Central Venous Catheters and Hemodialysis
- Cytokine Signaling Pathways and Interactions
- Circular RNAs in diseases
Asia University
2017-2024
Tri-Service General Hospital
2017
National Defense Medical Center
2017
National Yang Ming Chiao Tung University
2015
Taichung Veterans General Hospital
2002-2015
China Medical University
2009
Yuli Veterans Hospital
2008
The Coronal Plane Alignment of the Knee (CPAK) classification is a simple and comprehensive system for predicting pre-arthritic knee alignment. However, when CPAK applied in Asian population, which characterized by more varus wider distribution lower limb alignment, modifications boundaries arithmetic hip-knee-ankle angle (aHKA) joint line obliquity (JLO) should be considered. purposes this study were as follows: first, to propose modified based on actual (aJLO) range aHKA population;...
Abstract Peptidoglycan (PGN), the major component of cell wall Gram-positive bacteria, activates innate immune system host and induces release cytokines chemokines. We investigated signaling pathway involved in IL-6 production stimulated by PGN rheumatoid arthritis synovial fibroblasts. caused concentration- time-dependent increases production. PGN-mediated was attenuated TLR2 small interfering RNA nucleotide-binding oligomerization domain 2 RNA. Pretreatment with PI3K inhibitor (Ly294002...
Reasons for dissatisfaction with total knee arthroplasty (TKA) include unequal flexion or extension gap, soft tissue imbalance, and patella maltracking, which often occur mismatch between femoral tibial coronal bony alignment in the joint extremely varus valgus alignment. However, lower limb classification is based only on hip-knee-ankle angle (HKAA), leading to oversight regarding a We aimed classify of limbs according mechanical femur tibia healthy population.All 214 normal triple films...
Chondrosarcoma is a type of highly malignant tumor with capacity to invade locally and cause distant metastasis. shows predilection for metastasis the lungs. Adiponectin protein hormone secreted predominantly by differentiated adipocytes involved in energy homeostasis. However, effect adiponectin on migration activity human chondrosarcoma cells mostly unknown. We found that increased expression α2β1 integrin cells. The messenger RNA receptor (AdipoR1 AdipoR2) patients cell lines were...
Abstract Background Windswept deformity (WSD) in relation to advanced osteoarthritis (OA) presents a significant surgical challenge total knee arthroplasty (TKA). The primary goal of this study is investigate the Prevalance WSD associated who have undergone arthroplasty. secondary explore causes and its association with spinal or leg length discrepancy these patients. Finally, we evaluate outcomes phenotype-considered kinematically aligned TKA (KA-TKA) treating patients WSD. Methods A review...
Adipose-derived stem cells (ADSCs) are a type of mesenchymal cell that is investigated in bone tissue engineering (BTE). Osteoblasts the main responsible for formation vivo and directing ADSCs to form osteoblasts through osteogenesis research topic BTE. In addition into osteoblasts, crosstalk with secretion extracellular vesicles (EVs) may also contribute ADSC-based We effect ADSC-secreted EVs (ADSC-EVs) on osteoblast function. ADSC-EVs (size ≤ 1000 nm) were isolated from culture supernatant...
Abstract Background The kinematic alignment (KA) technique in total knee arthroplasty (TKA) aims to restore the native of pre-disease joint anatomy. Determining individualized targets is crucial for pre-operative planning, which can be set according different original phenotypes. Five most common phenotypes have been categorized KA-TKA target setting our previous study. purpose this study was investigate distribution five advanced OA patients and evaluate clinical outcomes phenotype-oriented...
The aim of our study was to investigate failure rates reconstruction plate and non-reconstruction plate, find the best strategy for implant selection different fracture types midshaft clavicular fractures. Two hundred twenty-six consecutive patients with fractures who received open reduction fixation during Jan 2012 July 2017 were reviewed. correlations between risk factors including demographic data, classifications, analyzed. AO/OTA classification are most important affecting...
Background and Objectives: Adequate pain management during early rehabilitation is mandatory for improving the outcomes of patients undergoing total knee arthroplasty (TKA). Conventional management, mainly comprising opioids epidural analgesia, may result in certain adverse effects such as dizziness, nausea, motor blockade. We proposed a multimodal analgesic (MA) strategy involving use peripheral nerve block (NB), periarticular injection (PAI), intravenous patient-controlled analgesia...
This study aimed to investigate the factors influencing decision of patients with severe knee osteoarthritis, who are covered by universal health insurance, undergo total replacement (TKR) surgery, as recommended orthopedic physicians. A questionnaire survey was used collect participants' demographics, socio-economic status, medical history, baseline Oxford Knee Score (OKS), and EuroQol-5 Dimension Questionnaire (EQ-5D). We included 704 which 487 underwent TKR (surgery group), while 217 did...
Flex foot device was one of the most common prosthesis for athletes with transtibial amputation on recent market. Thus, results investigation biomechanics flex would be a considerable impact performance disabled wearing foots. This study designed to investigate biomechanical condition different curvatures while standing and running by finite element analysis. demonstrated models established three 20[Formula: see text] (small bending), 35[Formula: (medium bending) 50[Formula: (big bending)....