A5040386169- Reconstructive Surgery and Microvascular Techniques
- Acute Ischemic Stroke Management
- RNA modifications and cancer
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Renal cell carcinoma treatment
- Circular RNAs in diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Electrospun Nanofibers in Biomedical Applications
- Pharmacological Receptor Mechanisms and Effects
- Extracellular vesicles in disease
- Venous Thromboembolism Diagnosis and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Cleft Lip and Palate Research
- Receptor Mechanisms and Signaling
- Ferroptosis and cancer prognosis
- Tissue Engineering and Regenerative Medicine
- Cervical Cancer and HPV Research
- Neurological Disease Mechanisms and Treatments
- Uterine Myomas and Treatments
- Health, psychology, and well-being
- RNA Research and Splicing
- Nerve injury and regeneration
- MicroRNA in disease regulation
Army Medical University
2020-2025
Hunan Cancer Hospital
2018-2025
Beijing University of Chinese Medicine
2025
Second Xiangya Hospital of Central South University
2022-2025
Jianghan University
2025
Central South University
2015-2025
Jiangnan University
2025
Yunnan Academy of Agricultural Sciences
2021-2025
Wuxi Fourth People's Hospital
2025
Hubei Zhongshan Hospital
2023-2024
Abstract During myocardial infarction, microcirculation disturbance in the ischemic area can cause necrosis and formation of fibrotic tissue, potentially leading to malignant arrhythmia remodeling. Here, we report a microchanneled hydrogel suture for two-way signal communication, pumping drugs on demand, cardiac repair. After our monitors abnormal electrocardiogram through mobile device triggers nitric oxide demand via sutures’ microchannels, thereby inhibiting inflammation, promoting...
Abstract Aerobic glycolysis (the Warburg effect) is a robust metabolic hallmark of most tumors, including oral squamous cell carcinoma (OSCC). Glucose transporter 1 (GLUT1), major glucose regulating the uptake, upregulated in OSCC and participated OSCC. The deregulation function noncoding RNAs cancers have been widely reported. Reportedly, hsa_circular RNA (circRNA)_100290 (circ_SLC30A7) significantly (fold change = 6.91, p < 0.0000001) According to online tools prediction (miRWalk,...
Oral cancer represents a significant proportion of head and neck malignancies, accounting for approximately 3 % all malignant tumors worldwide. Alternative splicing (AS), post-transcriptional regulatory mechanism, is increasingly linked to development. The precise impact AS on oral progression not well understood. Bioinformatics, semi-quantitative RT-PCR, minigene reporter system detect the skipping SLC37A4 exon 7 in cancer. FRAP, live cell immunofluorescence demonstrates that SRSF9 can...
Developing an ideal wound dressing that meets the multiple demands of safe and practical, good biocompatibility, superior mechanical property excellent antibacterial activity is highly desirable for healing. Bacterial cellulose (BC) one such promising class biopolymers since it can control exudates provide moist environment to a resulting in better However, lack has limited its application.We prepared flexible based on bacterial membrane then modified by chemical crosslinking prepare situ...
Long non-coding RNAs (lncRNAs) are important regulatory factors in tumor development and progression. The lncRNA CASC9.5 is located on chromosome 8 has a total length of 1316 bp. plays tumor-promoting role the progression brain colon cancer; however, limited research been conducted this lung adenocarcinoma. present study analyzed 44 adenocarcinoma specimens 2 cancer cell lines. It was found that expression levels were significantly higher tissues cells compared with normal tissues. In...
Chronic cerebral hypoperfusion induced cerebrovascular white matter lesions (WMLs) are closely associated with cognitive impairment and other neurological deficits. The mechanism of demyelination in response to has not yet been fully clarified. Soluble epoxide hydrolase (sEH) is an endogenous key enzyme the metabolic conversion degradation P450 eicosanoids called epoxyeicosatrienoic acids. Inhibition sEH suggested represent a prototype "combination therapy" targeting multiple mechanisms...
There is no effective and noninvasive solution for thrombolysis because the mechanism by which certain thrombi become tissue plasminogen activator (tPA)-resistant remains obscure. Endovascular thrombectomy last option these tPA-resistant thrombi, thus a new strategy urgently needed. Through an examination of retrieved from stroke patients, we found that neutrophil extracellular traps (NETs), ε-(γ-glutamyl) lysine isopeptide bonds fibrin scaffolds jointly comprise key chain in tPA resistance....
The body weight–based thrombolytic medication strategy in clinical trials shows critical defects recanalization rate and post-thrombolysis hemorrhage. Methods for perceiving thrombi heterogeneity of thrombolysis resistance is urgently needed precise thrombolysis. Here, we revealed the relationship between thrombin created an artificial biomarker-based nano-patrol system with robotic functional logic to perceive report thrombi. nano-patrols are contrallable able accomplish resistance-matched...
Cardiac sarcoidosis (CS) represents a rare yet potentially life-threatening condition characterized by non-specific clinical symptoms that maybe easily missed clinicians. In this case series, the presentations, various imaging modalities’ characteristics, and management of four patients, each with distinct phenotypes CS confirmed through endomyocardial biopsy, are discussed. Advanced techniques, including positron emission tomography, revealed focal septal uptake 18 F fluorodeoxyglucose,...
ABSTRACT This study aims to enhance selective compliance assembly robot arm (SCARA) 3D printers enable the reproduction of colors and creation multi‐colored 3D‐printed food. SCARA offer a promising solution for food printing, overcoming small printing spaces poor scalability delta printers. A reversal valve was assembled onto printer synchronized with movement robotic arm. system realized collaborative two‐color ink its positioning accuracy tested. Additionally, composite designed using...
Background: The Internet is increasingly utilized by researchers, health care providers, and the public to seek medical information. also provides a powerful tool for messaging. Understanding needs of intended audience how they use websites critical website developers provide better services users. Objective: aim study was examine utilization chronic fatigue syndrome (CFS) at Centers Disease Control Prevention (CDC). We evaluated (1) CFS utilization, (2) outcomes CDC awareness campaign, (3)...
Abstract The viability of using thrombus heterogeneity (TH) data derived from dual‐energy CT (DECT) as a visual thrombotic biomarker is unclear. first aim this study to develop quantitative measure TH on DECT and test its performance for predicting the stroke source (cardiogenic vs. non‐cardiogenic) clinical outcomes (functional status assessed by modified Rankin Scale score at 90 days) following machine thrombectomy (MT). second associate subregions with composition facilitate visualization...
Endometriosis is a chronic inflammatory disease with an uncertain pathogenesis. Peritoneal immune dysregulation plays important role in the pathogenesis of endometriosis. Exosomes are messengers intercellular communication. This study mainly investigated exosomes from uterine cavity aspirate fluid were isolated and cocultured macrophages for 48 h. Flow cytometry was used to detect macrophage polarization. A Human MAPK Phosphorylation Antibody Array Western blot phosphorylation pathway....
Abstract Spinal cord injury ( SCI ) involves complex pathological process which can be complicated by secondary injury. TREK ‐1 is a member of the two‐pore domain potassium (K2P) channel family, modulated number physiological and stimuli. Recent studies suggest that plays an active role in depression, pain neuroprotection. However, its after remains unclear. In this study, we tested expression function spinal mice traumatic . was widely expressed cord, including astrocytes neurons....
Abstract The kidney ankyrin repeat‐containing protein 1 (Kank1) gene is one of the most important members KANK family. Kank1 has hybridity deletion and promoter methylation in cancer tissues brain, lung, corresponding cell lines, leading to downregulation expression. Meanwhile, also plays a key role occurrence development various types tumors, suggesting that may be an anti‐oncogene. However, its potential mechanisms Oral Squamous Cell Carcinoma (OSCC) remain unclear. We examined expression...