A5073619397- Toxic Organic Pollutants Impact
- Per- and polyfluoroalkyl substances research
- Mesenchymal stem cell research
- Effects and risks of endocrine disrupting chemicals
- Pancreatitis Pathology and Treatment
- Electrospun Nanofibers in Biomedical Applications
- Acute Ischemic Stroke Management
- Tissue Engineering and Regenerative Medicine
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Health and Disease Prevention
- Angiogenesis and VEGF in Cancer
- Dermatologic Treatments and Research
- Autophagy in Disease and Therapy
- Gastrointestinal disorders and treatments
- Air Quality and Health Impacts
- Wound Healing and Treatments
- Heart Rate Variability and Autonomic Control
- Antimicrobial Resistance in Staphylococcus
- Cancer, Hypoxia, and Metabolism
- Laser Applications in Dentistry and Medicine
- Chemical Analysis and Environmental Impact
- Microplastics and Plastic Pollution
- Heme Oxygenase-1 and Carbon Monoxide
- Skin Diseases and Diabetes
- Prenatal Substance Exposure Effects
Jinan University
2025
Huzhou Central Hospital
2023-2025
National Cancer Institute
2024
National Institutes of Health
2024
Ministry of Ecology and Environment
2024
First Affiliated Hospital of Nanchang University
2021-2023
Nanchang University
2021-2023
Huzhou University
2021-2023
Wenzhou Medical University
2018-2022
Shanghai Jiao Tong University
2016-2022
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that activated upon exposure to hypoxic stress. It modulates number of cellular responses including proliferation, apoptosis, angiogenesis, and metabolism by activating panel target genes in response hypoxia. The HIF-1 level often upregulated the microenvironment solid tumors, which contributes cancer treatment failure. Here we report silver nanoparticles (AgNPs), are widely used as an antimicrobial agent, effective inhibitor...
An increasing number of studies have reported neonicotinoid insecticides (NEOs), the emerging alternatives to conventional insecticides, may increase oxidative stress and cause adverse health effects, but limited is known about prenatal NEOs exposures their impact on birth outcomes.We investigated levels exposure NEOs/metabolites, assess associations with outcomes, investigate whether these could be mediated by using 8-OHdG as biomarker.We studied 296 mother-infant pairs recruited from...
Per- and polyfluoroalkyl substances (PFASs) are widely used in China, but little is known about the association between prenatal PFASs exposure fetal reproductive development as well its potential mechanism.We investigated effects of cord blood on hormones mechanism relation to steroidogenic enzymes.Ten selected (n = 351) including PFOS, PFOA, PFBS, PFDA, PFDoA, PFHpA, PFHxS, PFNA, PFOSA, PFUA, two estradiol (E2) testosterone (T) 349) were measured 351 serum samples from a Chinese birth...
Abstract Background Hypertrophic scar (HS) that can lead to defects in appearance and function is often characterized by uncontrolled fibroblast proliferation excessive inflammation. Curcumin has been shown have anti‐inflammatory anti‐oxidative effects play an anti‐fibrotic role interfering transforming growth factor‐β1 (TGF‐β1)/Smads signaling pathways. Aim To study the effect mechanism of curcumin on HS from perspective activity inflammation regulation. Methods Cell proliferation,...
Green space may have a wide range of beneficial health effects, but its association with preterm birth (PTB) remains inconclusive. Therefore, our study aims to investigate the effect green and joint particulate matter (PM) on PTB. Additionally, we seek identify critical susceptibility window. This retrospective included 5,240,828 pregnant women in Guangdong Province from 2014 2018. Due clustering among women, generalized estimating equations were used examine effects PM pollution PTB, by...
Staphylococcus aureus is a zoonotic pathogen that causes various life-threatening diseases. The mechanisms of action amoxicillin against S. are unclear. Here, we established rabbit tissue cage infection model to evaluate the relationship between pharmacokinetic/pharmacodynamic (PK/PD) parameters and selective enrichment resistant strains elucidate evolution its resistance amoxicillin. was injected into cages at 1010 colony forming units (CFU)/mL. We different intramuscular concentrations...
Background:Metabolic syndrome (MetS) maybe associated with mild cognitive impairment (MCI). Objective:To investigate the relationship between MetS, its individual or combined components, and MCI among elderly. Methods:A case-control study was conducted elderly aged 65 years over in a community located southwestern suburb of Shanghai, China. The Chinese version Mini-Mental Status Examination (C-MMSE) used to screen subjects MCI. Associations MetS components were analyzed using conditional...
The study created mice model of Hashimoto's thyroiditis (HT) and induced thyroid inflammatory cell lines, exploring the mechanism Xiaoying Daotan decoction on HT.Divided HT models into group (0.2 mL saline), Western medicine levothyroxine sodium tablets), traditional Chinese Xiaoyin prescription), Notch protein inhibition prescription). After treatment, serum expression T (Treg)/T helper 17 (Th17) cytokines levels were detected through Enzyme linked immunosorbent assay (ELISA). Use real-time...
Abstract The improvement of fat graft viability might depend on the presence multipotent resident adipose derived stem cells (ADSCs) which is important component stromal vascular fraction (SVF). Vascular endothelial growth factor (VEGF) and angiogenin‐1 (Ang‐1) are responsible for neovascularization. However, their half‐life too short to produce a biological effect. We thus investigated whether VEGF‐ANG‐1‐polylactic acid (PLA) microspheres could enhance angiogenic properties ADSCs. PLA...