A5049334720- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Advanced Photocatalysis Techniques
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Treatments and Studies
- Electrocatalysts for Energy Conversion
- Drug Transport and Resistance Mechanisms
- Sarcoma Diagnosis and Treatment
- TiO2 Photocatalysis and Solar Cells
- Pediatric Hepatobiliary Diseases and Treatments
- Advanced Polymer Synthesis and Characterization
- Gallbladder and Bile Duct Disorders
- HER2/EGFR in Cancer Research
- Total Knee Arthroplasty Outcomes
- Cancer therapeutics and mechanisms
- Phytochemistry and biological activity of medicinal plants
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatitis Pathology and Treatment
- Copper-based nanomaterials and applications
- Thyroid Cancer Diagnosis and Treatment
- Renal and related cancers
Yonsei University
1993-2024
Inje University Busan Paik Hospital
2015-2024
Versus Arthritis
2024
Catholic University of Korea
2023
Inje University
2010-2017
General Department of Preventive Medicine
2015
Samsung (South Korea)
2011-2013
Gachon University
2012
Gachon University Gil Medical Center
2011
University of California, Los Angeles
2010
Abstract Oxygen vacancies have been treated as an important material engineering tool to enhance catalytic performance; for instance, oxygen suppress charge recombination at the Schottky interface, and thus, photocurrent can be improved. In this regard, gradient distribution of in n‐type metal oxides produces ideal band structure minimizing e − /h + by efficient hole extraction; however, its achievement remains a daunting challenge. Here, photoelectrochemical (PEC)‐driven “self‐purification”...
Cu is a key element for many photo- and electro-driven catalyst systems, but it readily undergoes natural oxidation in air electron-mediated support interactions when contact with reducible oxides. The production of value-added hydrocarbons via photocatalytic CO2 reduction promising, remains an unresolved challenge due to the hurdles associated controlling valence state cocatalyst within heterogeneous composite formed as result oxidative stabilization during nucleation process. Herein, we...
Abstract Solar energy utilization has drawn attention due to ever‐increasing environmental and issues. Photoelectrochemical (PEC) photocatalytic (PC) water splitting for hydrogen production, which is the most popular well‐established solar‐to‐chemical conversion process, been studied thoroughly date but now facing limitations related low efficiency. To resolve this issue, research in PEC cells or photocatalysts recently aimed produce alternative value‐added chemicals by modifying their redox...
Strong evidence is lacking as no confirmatory randomized controlled trials (RCTs) have compared the efficacy of totally laparoscopic distal gastrectomy (TLDG) with laparoscopy-assisted (LADG). The authors performed an RCT to confirm if TLDG different from LADG.
The glycerol oxidation reaction (GOR) run with photoelectrochemical cells (PECs) is one of the most promising ways to upgrade biomass because it thermodynamically favorable, while irreversible overoxidation leads unsatisfactory product selectivities. Herein, a tunable one-dimensional nanoconfined environment was introduced into GOR process, which accelerated mass transfer via microscale fluid effect and changed main from formic acid (FA) glyceraldehyde (GLD), led retention heavier...
Kidney podocytes and their slit diaphragms (SDs) form the final barrier to urinary protein loss. There is mounting evidence that SD proteins also participate in intracellular signaling pathways. The nephrin serves as a component of complex directly links podocyte junctional integrity actin cytoskeletal dynamics. Another protein, CD2-associated (CD2AP), an adaptor molecule involved homeostasis can repress proapoptotic TGF-beta podocytes. Here we show dendrin, originally identified...
Background Complete mesocolic excision (CME) has been proposed for colon cancer to improve oncological outcomes. The risks and benefits of laparoscopic CME have not examined fully. We compared short‐ long‐term outcomes with a conventional (non‐CME) in right hemicolectomy (RHC) right‐sided cancer. Methods In total, 115 patients who underwent RHC stage I–III at Busan Paik Hospital from August 2007 October 2011 were enrolled this case–control study. Three trained colorectal surgeons reviewed...
In heterogeneous catalysts, metal-oxide interactions occur spontaneously but often in an undesired way leading to the oxidation of metal nanoparticles. Manipulating such produce highly active surface nanoparticles can warrant optimal catalytic activity has not been established date. Here we report that a prior reduced TiO2 support reverse interaction with Pt and augment metallic state Pt, exhibiting 3-fold increase hydrogen production rate compared conventional Pt/TiO2. Spatially resolved...
The occurrence of resistance to chemotherapeutic drugs is a major problem for successful cancer treatment and reducing drug accumulation by P-glycoprotein (P-gp) one the mechanisms multidrug (MDR). present study was performed evaluate MDR-reversal abilities two bis benzylisoquinoline alkaloids, tetrandine (TET) fangchinoline (FAN), compared with verapamil (VER), well-known P-gp modulator. TET (3.0 μM), FAN μM) VER (10.0 reduced paclitaxel (TAX) concentration required achieve 50% inhibition...
Purpose: This study analyzed the physiological activity, cytotoxicity, anti-inflammatory, and whitening effects of hot water extracts from roots leaves <i>Ixeris dentata</i> to determine optimal extraction conditions. Further, their potential as functional cosmetic materials were evaluated.Methods: Extracts obtained wild cultivated <i>I. using (room temperature 100°C). The antioxidant bioactive compound content (total phenolic (TPC), total flavonoid (TFC), anti-inflammatory...
Purpose: This study investigated the potential of <i>Actaea heracleifolia</i> root extract as a functional natural material by analyzing its effects on antioxidant and anti-bacterial effect activity; polyphenol flavonoid content; cytotoxicity; nitric oxide (NO), elastase, human matrix metalloproteinase-1 (hMMP-1) production. Methods: Dried <i>A. roots were ground, extracted with methanol, freeze-dried. Various assessments conducted, including free radical scavenging,...
FOLFOX-based adjuvant chemotherapy is a benefit for high-risk stage II and III colon cancer after curative resection. But, the prognostic factor or predictive marker efficacy of FOLFOX remains unclear. This study was aimed to identify value cumulative impact on patients. A total 196 patients were retrospectively enrolled in prospectively collected data. They underwent resection followed by FOLFOX4 chemotherapy. The oncological outcomes included 5-year disease-free survival (DFS) rate overall...
1. Fimasartan is an angiotensin receptor II antagonist used to treat patients with hypertension. This drug mainly excreted into bile as either the parent compound or a glucuronide conjugate. In this study, we examined glucuronidation of fimasartan and characterized UDP-glucuronosyltransferases (UGTs) responsible for glucuronidation.2. Only one type was observed after incubation pooled human liver microsomes (HLMs) identified N2-glucuronide based on comparison authentic standard.3. Among 12...
Micellization behavior of (AB)n type star-block copolymer in a selective solvent for its outer block is investigated by using Brownian dynamics simulation. Micellar properties are compared terms the arm number (n) copolymer. It observed that critical micelle concentration (cmc) shows minimum when cmc plotted against number. The with longer soluble at smaller than shorter block. Although multiple arms forms more compact core as to diblock copolymer, average aggregation inversely proportional...
Purpose This experimental study verified the effect of adipose-tissue-derived stem cells (ASCs) on healing ischemic colonic anastomoses in rats. Methods ASCs were isolated from subcutaneous fat tissue rats and identified as mesenchymal by identification different potentials. An animal model anastomosis was induced modifying Nagahata's method. Sixty male Sprague-Dawley (10-week-old, 370 ± 50 g) divided into two groups (n = 30 each): a control group which sutured single layer with 6-0...
Proliferation marker Ki-67 is widely used in cancer prognosis prediction. We tried to investigate the role of as a prognostic factor stomach after surgery this study.We retrospectively evaluated 251 patients who underwent curative resection for gastric from 2010 2015. In pathologic examination, labeling index was defined percentage antigen positive cells. Prognostic significance evaluated. Disease-free survival (DFS) assessed primary end-point.The median follow-up period 28.0 months....