A5031140014- COVID-19 epidemiological studies
- COVID-19 Pandemic Impacts
- Human Mobility and Location-Based Analysis
- COVID-19 and Mental Health
- Global Health Workforce Issues
- Delphi Technique in Research
- Cerebral Palsy and Movement Disorders
- Urban Transport and Accessibility
- Data-Driven Disease Surveillance
- COVID-19 Digital Contact Tracing
- Infection Control and Ventilation
- Influenza Virus Research Studies
- Parasitic Infections and Diagnostics
- Legal Systems and Judicial Processes
- Pediatric health and respiratory diseases
- Viral Infections and Outbreaks Research
- Impact of Light on Environment and Health
- Transportation and Mobility Innovations
- Glioma Diagnosis and Treatment
- Mathematical and Theoretical Epidemiology and Ecology Models
- Global Health Care Issues
- Epigenetics and DNA Methylation
- Colonialism, slavery, and trade
- Criminal Justice and Corrections Analysis
- Criminal Law and Evidence
University of Southampton
2018-2022
Imperial College London
2015-2017
The University of Texas Health Science Center at San Antonio
2014
Abstract Background The COVID-19 outbreak containment strategies in China based on non-pharmaceutical interventions (NPIs) appear to be effective. Quantitative research is still needed however assess the efficacy of different candidate NPIs and their timings guide ongoing future responses epidemics this emerging disease across World. Methods We built a travel network-based susceptible-exposed-infectious-removed (SEIR) model simulate cities mainland China. used epidemiological parameters...
Better relaxing lockdown together Even during a pandemic, all countries—even islands—are dependent in one way or another on their neighbors. Without coordinated relaxation of nonpharmaceutical interventions (NPIs) among the most closely connected countries, it is difficult to envisage maintaining control infectious viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ruktanonchai et al. used mobility data from smartphones estimate movements between administrative...
The coronavirus disease 2019 (COVID-19) pandemic has posed substantial challenges to the formulation of preventive interventions, particularly since effects physical distancing measures and upcoming vaccines on reducing susceptible social contacts eventually halting transmission remain unclear. Here, using anonymized mobile geolocation data in China, we devise a mobility-associated contact index quantify impact both vaccination unified way. Building this index, our epidemiological model...
Human mobility is fundamental to understanding global issues in the health and social sciences such as disease spread displacements from disasters conflicts. Detailed data across spatial temporal scales are difficult collect, however, with movements varying short, repeated work or school, rare migratory national borders. While typical sources of travel history surveys GPS tracker can inform different typologies movement, almost no source readily obtainable address all types movement at once....
It is estimated that pneumonia responsible for 15% of childhood deaths worldwide. Recent research has shown hypoxia and malnutrition are strong predictors mortality in children hospitalized pneumonia. under 5 who have hypoxaemia around 1.5 million with severe require oxygen treatment each year. We developed a deterministic compartmental model links the care pathway to disease progression assess impact introducing pulse oximetry as prognostic tool distinguish from non-severe under-5 year olds...
2020 was an unprecedented year, with rapid and drastic changes in human mobility due to the COVID-19 pandemic. To understand variation commuting patterns among Chinese population across stable unstable periods, we used nationwide data from 318 million mobile phone users China examine extreme fluctuations of movements 2020, ranging Lunar New Year travel season (chunyun), exceptional calm lockdown, then recovery period. We observed that cross-city movements, which increased substantially...
Background Malaria transmission has declined substantially in the 21st century, but pregnant women areas of sustained still require protection to prevent adverse pregnancy and birth outcomes associated with malaria (MiP). A recent call action been issued address continuing low coverage intermittent preventive treatment (IPTp). This has, however, questioned by some, part due concerns about resistance sulphadoxine-pyrimethamine (SP), only drug currently recommended for IPTp. Methods findings...
Travel restrictions and physical distancing have been implemented across the world to mitigate coronavirus disease 2019 (COVID-19) pandemic, but studies are needed understand their effectiveness regions time. Based on population mobility metrics derived from mobile phone geolocation data 135 countries or territories during first wave of pandemic in 2020, we built a metapopulation epidemiological model measure effect travel contact containing COVID-19 outbreaks regions. We found that if these...
BackgroundThe COVID-19 pandemic has posed an ongoing global crisis, but how the virus spread across world remains poorly understood. This is of vital importance for informing current and future response strategies.
Abstract As rates of new COVID-19 cases decline across Europe due to non-pharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how ease restrictions while minimizing the risk resurgent outbreaks. Here, we use mobility case data quantify coordinated exit strategies could delay continental resurgence limit community transmission COVID-19. We find that a epidemic occur many 5 weeks earlier when well-connected with stringent existing...
Human and livestock mobility are key factors in the transmission of several high-burden zoonoses such as rift valley fever trypanosomiasis, yet our knowledge this is relatively poor due to difficulty quantifying population-level movement patterns. Significant variation patterns individual hosts means it necessary capture their fine-scale order gain useful that can be extrapolated a population level. Here we explore how movements people ruminants, exposure various types land cover, correlate...
Abstract Travel and physical distancing interventions have been implemented across the World to mitigate COVID-19 pandemic, but studies are needed quantify effectiveness of these measures regions time. Timely population mobility data were obtained measure travel contact reductions in 135 countries or territories. During 10 weeks March 22 – May 30, 2020, domestic study has dramatically reduced a median 59% (interquartile range [IQR] 43% - 73%) normal levels seen before outbreak, with...
Summary Modern transportation plays a key role in the long-distance and rapid spread of SARS-CoV-2. However, little is known about transmission risk SARS-CoV-2 on confined vehicles, such as airplanes trains. Based itinerary epidemiological data COVID-19 cases close contacts among 9,265 airline passengers 291 29,335 830 high-speed trains China from December 20, 2019 to March 17, 2020, we estimated that upper bound overall attack rate was 0.60% (95% confidence interval: 0.43%-0.84%) for 0.35%...
Modern transportation plays a key role in the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and new variants. However, little is known about exact transmission risk virus on airplanes.Using itinerary epidemiological data disease 2019 (COVID-19) cases close contacts domestic airplanes departing from Wuhan city China before lockdown 23 January 2020, we estimated upper lower bounds overall COVID-19 among travelers.In total, 175 index were identified 5797 passengers 177...
Abstract: This article investigates the chantey "Serafina" from unpublished collection of erotic folklore collector Gershon Legman. The song is a part unexpurgated repertoire famed singer and Stan Hugill who provided to Legman for songs that he intended publish. Specifically, this discusses potential origin importance song—which representation sailing work sea—and addresses ways in which content reproduces perceptions anxieties around prostitutes, sailors, venereal disease. main character,...
Abstract Given the increasing evidence that domestic contact with livestock is a risk factor for child diarrhoea in low- and middle-income countries, there have been calls greater quantification of human-livestock such countries. This study aimed to quantify seasonality cattle proximity water sources household compounds develop preliminary landscape model faecal deposition by cattle. A total 120 smallholder herds Asembo area Siaya County, Kenya, were tracked over 1 week April 2018 July...
Abstract COVID-19 resurgences worldwide have posed significant challenges to the formulation of preventive interventions, especially given that effects physical distancing and upcoming vaccines on reducing susceptible social contacts eventually halting transmission are still unclear. Using anonymized mobile geolocation data in China, we devised a mobility-associated contact index quantify impact both vaccination measures unified way such gap between intervention disease can be explicitly...
BACKGROUND: Glioblastoma (GBM) remains an incurable malignancy with rapid progression and poor survival. GBM exhibits a hypoxic nature, treatment bevacizumab (BEV) may increase intratumoral hypoxia. TH-302 is investigational prodrug that selectively releases the DNA cross-linker (Br-IPM) under conditions. A phase I/II trial (NCT01403610) evaluating safety efficacy of combined BEV in patients BEV-refractory investigating pharmacodynamics biomarkers. METHODS: Patients were randomized to single...
Improving rural household access to resources such as markets, schools and healthcare can help alleviate poverty in low-income settings. Current models of geographic accessibility various rarely take individual variation into account due a lack appropriate data, yet understanding mobility at an level is key knowing how people their local resources. Our study used both activity-specific survey GPS trackers evaluate adults area western Kenya accessed We calculated the travel time spent six...