A5064785124- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Platelet Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Cardiac Imaging and Diagnostics
- Adipose Tissue and Metabolism
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Atherosclerosis and Cardiovascular Diseases
- Multiple Myeloma Research and Treatments
- Inflammasome and immune disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Peroxisome Proliferator-Activated Receptors
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- PI3K/AKT/mTOR signaling in cancer
- Protease and Inhibitor Mechanisms
- Acute Myocardial Infarction Research
- Muscle and Compartmental Disorders
- Birth, Development, and Health
- Nuclear Receptors and Signaling
- COVID-19 and healthcare impacts
- Acute Kidney Injury Research
- Pituitary Gland Disorders and Treatments
Cliniques Universitaires Saint-Luc
2020-2024
UCLouvain
2012-2024
Institut Universitaire de Recherche Clinique
2019
Centre Hospitalier de Wallonie Picarde
2015
We compared the effects of total thyroidectomy (TTx) and radioiodine (RAI) administration on course thyroid hormones thyroid-stimulating immunoglobulins (TSI) in patients with Graves' disease.We retrospectively studied 80 initially treated antithyroid drugs requiring either RAI (8.3 ± 1.7 mCi (131)I; n = 40) or TTx (n as second-line therapy.The groups were not different, except for larger goiter, higher FT3 more frequent orbitopathy at diagnosis surgery group (p < 0.05). A persistent...
New transcatheter aortic valves were recently developed, enabling to resheath and reposition the prosthesis. The aim of present study was investigate whether manoeuvre did not impair outcome patients bioprosthesis durability after valve implantation (TAVI).On 346 consecutive (84 ± 7 yrs-old, mean STS 6.7 5%) undergoing a transfemoral TAVI in our institution since January 2008, 170 implanted using self-expanding (SEV). Among those, 39 (Group 1) required resheathing achieve successful...
Adenosine monophosphate-activated protein kinase (AMPK) acetyl-CoA carboxylase (ACC) signaling is activated in platelets by atherogenic lipids, particularly oxidized low-density lipoproteins, through a CD36-dependent pathway. More interestingly, increased platelet AMPK-induced ACC phosphorylation associated with the severity of coronary artery calcification as well acute events disease patients. Therefore, potential marker for risk stratification suspected The inhibition resulting from its...
A 53-year-old male was admitted for typical acute chest pain. The ECG showed a mirror image of posterior myocardial ischemia. Initial biology normal but cardiac markers (creatine kinase and troponin) rose later. Echocardiography did not reveal any hypokinetic segment. There no left ventricular dysfunction or valvular disease. pericardial effusion aortic dissection image. This patient treated as “non-ST segment elevation infarction” (NSTEMI), also called subendocardial infarction. selective...
Platelet inhibition is the main treatment strategy to prevent atherothrombotic complications after acute coronary syndrome or percutaneous intervention. Despite dual antiplatelet therapy (DAPT) combining aspirin and a P2Y12 receptor inhibitor, high on-treatment platelet reactivity (HPR) persists in some patients due poor response associated with ischemic risk. Tubulin acetylation has been pointed out as hallmark of stable microtubules responsible for discoid shape resting platelets. However,...
Introduction: Acetyl-CoA Carboxylase (ACC), the downstream specific substrate of AMP-activated protein kinase, is mainly phosphorylated in response to thrombin compared other platelet agonists.In clinical situation, such as coronary artery disease (CAD), associated with generation, ACC phosphorylation (P-ACC) can be an interesting marker action on platelets.Platelet P-ACC help us better understand complex interplay between activation and formation CAD.Aims: In current prospective trial...