- Dermatologic Treatments and Research
- Photodynamic Therapy Research Studies
- Vascular Malformations and Hemangiomas
- Acne and Rosacea Treatments and Effects
- Central Venous Catheters and Hemodialysis
- Tattoo and Body Piercing Complications
- Advanced Radiotherapy Techniques
- melanin and skin pigmentation
- Vascular Tumors and Angiosarcomas
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Facial Rejuvenation and Surgery Techniques
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Photoacoustic and Ultrasonic Imaging
Sichuan University
2022-2024
West China Hospital of Sichuan University
2022-2024
Sichuan Center for Disease Control and Prevention
2022
Port-wine stains are defined as congenital benign vascular lesions. The treatment of port-wine remains a challenge, worldwide. This study aimed to analyze the histological characteristics in different types and provide guidance for clinical decision-making.Biopsies were from hospital 2015 2021. H&E staining, Immunofluorescence Masson's trichrome staining Weigert performed on tissues.A total 35 patients included four distinct types, namely red (11 cases), purple (seven hypertrophic (nine...
Mesotherapy is a popular treatment that delivers substances deep into the skin but induces foreign body-type granulomatous reactions. However, such reactions caused by unauthorized use of topical tranexamic acid products in mesotherapy have never been reported before. We herein demonstrated case 33-year-old woman with multiple mesotherapy-induced granulomas disseminated across her face. The patient was diagnosed echo-color Doppler (ECD) and successfully treated medications including...
Port wine stains (PWS) are vascular malformations, and photodynamic therapy (PDT) is a promising treatment. Emerging drug delivery methods employ nanoparticles (NPs) to enhance permeability retention in diseased blood vessels improve bioavailability. (-) -epigallocatechin-3-gallate glycine (EGCG) has anti-angiogenetic effects boosts therapy. Chlorin e6 (Ce6) capable of efficiently producing singlet oxygen, rendering it very photosensitizer for utilization nanomedicine.
Abstract: Port-wine birthmark (PWB) are congenital vascular malformations that commonly occur on the face and neck, with an incidence of 0.3– 0.5% in general population, causing significant negative psychological effects economic burden to patients. Nevertheless, amidst plethora different treatment methods for PWB, choosing option best suits patient’s need can be a challenge. In recent years, traditional PWB have been replaced by new therapies, radioactive nuclide patch therapy is one them....
A combination of polyphenol with near infrared photodynamic therapy (PDT) and vascular-targeting nanoparticles holds significant promise as a potential treatment for port-wine stains (PWS). The anti-angiogenic properties the polyphenol, along targeted approach ability PDT to selectively damage tissue, make this particularly compelling. Using EOMA cells invitro experiment examine anti-angiogenesis effects using ELC, which is self-assembly Epigallocatechin-3-gallate (EGCG) loading Ce6...
Port-wine stains (PWS) are predominantly located on the face and neck. Hence, PWS affect not only aesthetic appearance but may also cause psychological distress. However, very few studies have researched quality of life (QoL) in Chinese patients with PWS.To evaluate QoL PWS.Skindex-29 Dermatology Life Quality Index (DLQI) were used to investigate healthy controls.In total, 198 adults 200 controls included. The scores symptomatic, emotional functional dimensions Skindex-29 observational group...