Abstract Background Antibiotic-associated diarrhea (AAD), defined as that occurs in association with the administration of antibiotics and without another clear etiology, is one most common adverse drug events therapy. We established a model induced by gentamycin cefradine to investigate microbiota characteristics intestinal lumen mice AAD provide insights into noteworthy bacteria related gentamicin cefradine-associated diarrhea. Results The number OTUs group normal was 983 2107,...

Although reports have provided evidence that diarrhea caused by Folium sennae can result in intestinal microbiota diversity disorder, the bacterial characteristic and specific mechanism are still unknown. The objective of our study was to investigate sennae, which associated with reshaping metabolic abnormality.For intervention extracts, Chao1 index Shannon were statistical decreased. Beta clusters mice interfered extracts distinctly separated from control group. Combining PPI network...

Repeated stress-related diarrhea is a kind of functional bowel disorders (FBDs) that are mainly stemming from dysregulation the microbiota–gut–brain axis mediated by complex interplay 5-hydroxytryptophan (5-HT). Intestinal content and intestinal mucosa microbiota belong to two different community systems, role systems in repeated remains largely unknown. In order ascertain difference composition potential function between response on diarrhea, we collected contents mice with for 16S rRNA...

The current research tried to explore the effect of Qiweibaizhu powder (QWBZP) on bacterial diversity and community structure intestinal mucosa dysbiosis diarrhea mice provide a scientific basis for efficacy QWBZP antibiotic-induced diarrhea. A mouse model was constructed with broad-spectrum antibiotics through mixture cephradine capsules gentamicin sulfate (23.33 mL·kg -1 ·d ). Intestinal collected, DNA extracted from each group. characteristics in were analyzed by MiSeq sequencing based...

ABSTRACT Background To assess the Knowledge, Attitude, and Practice (KAP) of medical students at Hunan Medicine College towards insomnia TCM treatment. Methods The study included 676 students. More than half were female (64.20%), 33.8% reported experiencing for over a week. Participants' KAP scores evaluated on treatment using scale. Results mean 58.93%, 73.75%, 64.94%, respectively, indicating insufficient knowledge but positive attitudes moderate practices. 78.18%, suggesting better...

Background Tongxieyaofang (TXYF) was a traditional Chinese medicine (TCM) formula for the treatment of diarrhea with liver stagnation and spleen deficiency syndrome, but potential targets mechanisms have not been fully clarified. This study aims to explore TXYF in alleviating using network pharmacology full-length 16S rRNA gene sequencing. Methods Network applied identify bioactive compounds involved role diarrhea. Meanwhile, model syndrome constructed by intragastric administration Folium...

Abstract Background: Antibiotic-associated diarrhea (AAD), defined as that occurs in association with the administration of antibiotics and without another clear etiology, is one most commonly adverse drug events therapy. We established a model induced by gentamycin cefradine to investigate microbiota characteristics intestinal lumen mice AAD provide insights into noteworthy bacteria related gentamicin cefradine-associated diarrhea. Results: The number OTUs group normal was 983 2107,...

Abstract Background: Although reports have provided evidence that diarrhea caused by Folium sennae can result in intestinal microbiota diversity disorder, the bacterial characteristic and specific mechanism are still unknown. The objective of our study was to investigate , which associated with reshaping metabolic abnormality. Results: For intervention extracts, Chao1 index Shannon were statistical decreased. Beta clusters mice interfered extracts distinctly separated from control group....

Abstract Background: Antibiotic-associated diarrhea (AAD), defined as that occurs in association with the administration of antibiotics and without another clear etiology, is one most commonly adverse drug events therapy. We established a model induced by gentamycin cefradine to investigate microbiota characteristics intestinal lumen mice AAD provide insights into noteworthy bacteria related gentamicin cefradine-associated diarrhea.Results: The number OTUs group normal was 983 2107,...

Abstract (1) Background: Although reports have provided evidence that diarrhea caused by Folium sennae can result in intestinal flora diversity disorder, the bacterial characteristic and specific mechanism are still unknown. The objective of our study was to investigate , which associated with reshaping metabolic abnormality. (2) Methods: contents 2 groups mice, intervened extracts distilled water respectively, were collected its DNA extracted for high-throughput sequencing analysis. active...

Abstract Background Antibiotic-associated diarrhea (AAD), defined as that occurs in association with the administration of antibiotics and without another clear etiology, is one most commonly adverse drug event therapy. We established a model induced by gentamycin cefradine to investigate microbiota characteristics intestinal lumen mice AAD provide insights into noteworthy bacterial related gentamicin cefradine-associated diarrhea. Results The number OTUs group normal was 983 1235,...