A5084018944- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Renal Transplantation Outcomes and Treatments
- Viral Infections and Immunology Research
- Angiogenesis and VEGF in Cancer
- Cardiovascular Function and Risk Factors
- Organ and Tissue Transplantation Research
- Organ Transplantation Techniques and Outcomes
- Cardiac Valve Diseases and Treatments
- Fuel Cells and Related Materials
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Cardiomyopathy and Myosin Studies
- Polyomavirus and related diseases
- Long-Term Effects of COVID-19
- Pulmonary Hypertension Research and Treatments
- Acute Lymphoblastic Leukemia research
- Atrial Fibrillation Management and Outcomes
- Tissue Engineering and Regenerative Medicine
- Cardiac Imaging and Diagnostics
- Pneumocystis jirovecii pneumonia detection and treatment
Mayo Clinic
2012-2025
Mayo Clinic in Florida
2012-2025
Mayo Clinic in Arizona
2011-2025
WinnMed
2009-2019
Mayo Clinic Hospital
2018
Nebraska Medical Center
2012
Univar (United States)
2012
Barry Callebaut (Belgium)
2011-2012
University of Minnesota Rochester
2011
In-Q-Tel
2009
Left ventricular assist device (LVAD) is being increasingly used in patients with end-stage dilated and ischemic cardiomyopathy. There have been no clinical trials addressing the use of LVAD therapy heart failure caused by restrictive (RCM) or hypertrophic cardiomyopathy (HCM). The purpose this study was therefore to analyze outcome these patients.Eighty-three received continuous axial flow (Heart mate II, Thoratec, Pleasanton, CA) from February 2007 May 2010 at our institution. We analyzed...
Background— Operative mortality after left ventricular assist device (LVAD) implantation is heavily influenced by patient selection and the technical difficulty of surgery. However, how we treat our patients LVAD setting may affect outcome beyond this period. We postulated that presence echocardiographic variables 1 month surgery suggesting appropriate degree LV unloading an adequate forward flow would be important in determining clinical outcomes initial successful implantation. Methods...
We retrospectively analyzed the potential of sirolimus as a primary immunosuppressant in long-term attenuation cardiac allograft vasculopathy progression and effects on cardiac-related morbidity mortality.Forty-five transplant recipients were converted to 1.2 years (0.2, 4.0) after transplantation with complete calcineurin inhibitor withdrawal. Fifty-eight control subjects 2.0 6.5 years) from maintained inhibitors. Age, sex, ejection fraction, time baseline intravascular ultrasound study not...
Digoxin is considered contraindicated in light-chain (AL) amyloidosis, given reports of increased toxicity published 30-50 years ago. We sought to determine the frequency digoxin patients with AL.We identified 107 AL amyloidosis who received between 2000 and 2015.The median age was 65 dose estimated glomerular filtration rate were 0.125 mg/d 55 ml/min/1.73 m2, respectively. reduced 16% patients, mainly due high serum drug concentration or worsening renal function. The duration therapy 5...
Although a link between donor-specific antibodies against human leukocyte antigens type II (DSA II+) and transplant glomerulopathy has been clearly established, its role in cardiac allograft vasculopathy (CAV) is unclear.Donor-specific were evaluated using solid-phase single-antigen bead assay before transplantation 51 heart recipients. Coronary angiography three-dimensional intravascular ultrasound performed at baseline approximately 1 year after the examination.There 4 (7.8 %), 11 (21.5%),...
In Brief Background We evaluated whether combined heart and liver transplant (H+LTx) can protect the graft from development of cardiac allograft vasculopathy using coronary three-dimensional (3D) volumetric intravascular ultrasound (IVUS). Methods From 2004 to 2009, we identified 24 isolated (HTx) 10 H+LTx recipients in whom two 3D IVUS studies were performed 1 year apart. Baseline was at 0.22 (0.17–1.16) years after transplantation, with follow-up exams baseline exam (0.96 [0.83–1.08])....
Axial flow left ventricular assist device (LVAD) implantation is an effective therapy for patients with advanced heart failure. As the preoperative hepatic and renal function play a critical role in determining adverse events after LVAD implantation, we analyzed predictive of model end-stage liver disease (MELD) score in-hospital mortality surgery. One hundred twenty-six underwent implant at our institution. Their individual MELD scores perioperative total blood product usage (TBPU) were...
The causes of encephalopathy in the posttransplant setting are diverse and include medication toxicity (e.g., posterior reversible syndrome), infections human herpes virus type 6 [HHV-6]), neoplastic disease (posttransplant lymphoproliferative disorder). Autoimmune etiologies not well recognized this setting, although a few cases described.1–5 Herein, we report 3 patients with autoimmune encephalitis (AE).
Abstract Background The prognosis in patients with advanced cardiac amyloidosis (CA) remains poor. Objectives We sought to describe survival post heart transplantation (HT) amyloid compared non‐amyloid recipients, highlight waitlist times within the new allocation system across three Organ Procurement and Transplantation Network (OPTN) regions, multiorgan (MOT) hereditary amyloidosis. Methods This is a retrospective review of end‐stage CA who underwent HT at Mayo Clinic from January 2007...
Left ventricular assist device (LVAD) thrombosis typically presents late and may have devastating consequences for patients. While LVAD pump is uncommon with current designs, many patients worldwide remain supported previous generations of LVADs, including the HeartWare (HVAD). Researchers focused on investigating acoustic signatures LVADs to enable earlier detection treatment this condition. This study explored use machine learning algorithms predict from harmonic power values determined a...