A5050869733- Electromagnetic wave absorption materials
- Advanced Antenna and Metasurface Technologies
- Metamaterials and Metasurfaces Applications
- Tribology and Wear Analysis
- Lubricants and Their Additives
- Numerical methods in engineering
- Polyamine Metabolism and Applications
- Planetary Science and Exploration
- MicroRNA in disease regulation
- Blood properties and coagulation
- Retinal Diseases and Treatments
- MXene and MAX Phase Materials
- 3D Printing in Biomedical Research
- Granular flow and fluidized beds
- Aluminum Alloy Microstructure Properties
- Advanced machining processes and optimization
- Surface Modification and Superhydrophobicity
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Caveolin-1 and cellular processes
- Particle Dynamics in Fluid Flows
- Fatigue and fracture mechanics
- Structural Engineering and Vibration Analysis
- RNA Research and Splicing
- Dental materials and restorations
Second Affiliated Hospital of Guangzhou Medical University
2017-2025
Guangzhou Medical University
2016-2025
Xuchang University
2025
Beijing Institute of Technology
2025
Tianjin University
2014-2024
Northwestern Polytechnical University
2020-2024
Shanghai Urban Construction Design and Research Institute (Group)
2024
Nanjing Normal University
2024
Hebei University of Technology
2024
China University of Geosciences (Beijing)
2024
Diabetic retinopathy (DR) has become a leading cause of global blindness as microvascular complication diabetes. Regular screening diabetic is strongly recommended for people with diabetes so that timely treatment can be provided to reduce the incidence visual impairment. However, DR not well carried out due lack eye care facilities, especially in rural areas China. Artificial intelligence (AI) based emerged novel strategy and show promising diagnostic performance sensitivity specificity,...
To assess the genotoxic effect of airborne particulate matter on corneal epithelial cells and investigate role reactive oxygen species (ROS) formation in this process.Immortalized human (HCECs) primary bovine were exposed to collected from Guangzhou for 24 hours. The cell viability toxicity measured by CCK-8 test lactate dehydrogenase (LDH) release, respectively. DNA breaks repair examined alkaline comet assay immunofluorescence staining phosphorylated histone variant H2AX (γH2AX), Reactive...
Abstract As rising stars of the aerogel family, metal aerogels (MAs) manifest broad prospects for combining features nanostructured metals and aerogels. However, restricted by insufficient mechanistic understanding limited strategies, structure‐tailored fabrication MAs remains challenging. Here, unveiling utilizing triple roles (initiator, ligand, solvent) played imidazolium‐based ionic liquids (ILs), a robust universal method is developed, yielding diverse ligament‐size‐tailored at ambient...
The X chromosome-linked inhibitor of apoptosis protein (XIAP) is the most potent intrinsic caspase and plays an important role in maintenance intestinal epithelial integrity. RNA binding protein, HuR, regulates stability translation many target transcripts. Here, we report that HuR associated with both 3′-untranslated region coding sequence mRNA encoding XIAP, stabilized XIAP transcript elevated its expression cells. Ectopic overexpression or cytoplasmic levels endogenous by decreasing...
microRNAs (miRNAs) and RNA-binding proteins (RBPs) jointly regulate gene expression at the posttranscriptional level are involved in many aspects of cellular functions. The RBP CUG-binding protein 1 (CUGBP1) destabilizes represses translation several target mRNAs, but exact mechanism that regulates CUGBP1 abundance remains elusive. In this paper, we show miR-503, computationally predicted to associate with three sites mRNA, expression. Overexpression an miR-503 precursor (pre-miR-503)...
The amino acid-derived polyamines are organic cations that essential for growth in all mammalian cells, but their exact roles at the molecular level remain largely unknown. Here we provide evidence promote translation of cyclin-dependent kinase 4 (CDK4) by action CUG-binding protein 1 (CUGBP1) and microRNA-222 (miR-222) intestinal epithelial cells. Both CUGBP1 miR-222 were found to bind CDK4 mRNA coding region 3'-untranslated repressed synergistically. Depletion cellular increased...
Rationale: Postmenopausal atherosclerosis (AS) has for decades been attributed to estrogen deficiency. Although the follicular stimulating hormone (FSH) levels rise sharply in parallel, direct effect of FSH on AS never investigated. In this study, we explored possible role development AS. Methods: This was a prospective cohort study 48 healthy premenopausal and 15 postmenopausal women. ApoE knockout mice were used as model human umbilical vascular endothelial cells (HUVECs) cultured cell...