A5004475622- Islamic Studies and History
- Turkey's Politics and Society
- Ottoman Empire History and Society
- Genomic variations and chromosomal abnormalities
- American Constitutional Law and Politics
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- European Political History Analysis
- Gastric Cancer Management and Outcomes
- Congenital heart defects research
- Jewish and Middle Eastern Studies
- Genomics and Rare Diseases
- Archaeology and Historical Studies
- Families in Therapy and Culture
- Sarcoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Archaeological Research and Protection
- Osteoarthritis Treatment and Mechanisms
- Contact Dermatitis and Allergies
- Colonialism, slavery, and trade
- Lymphatic System and Diseases
- Ottoman and Turkish Studies
- Helicobacter pylori-related gastroenterology studies
- Socioeconomic Development in MENA
- Inflammatory mediators and NSAID effects
Lymphedema Therapy (United States)
2024
Andrews University
2023
Claremont McKenna College
2012-2022
Loma Linda University
2012-2021
Sunnybrook Health Science Centre
2017
Health Sciences Centre
2017
Brigham and Women's Hospital
2003-2016
University of California, Berkeley
2011
McMaster University
2010
Harvard University
2003-2008
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, segmental duplications were integrated at level with medical genetic data, including 440 rearrangement breakpoints associated disease. This approach enabled discovery candidate genes for developmental diseases autism.
Complex central nervous system (CNS) malformations frequently coexist with other developmental abnormalities, but whether the associated defects share a common genetic basis is often unclear. We describe five individuals who phenotypically related CNS and in some cases urinary tract defects, also haploinsufficiency for NFIA transcription factor gene due to chromosomal translocation or deletion. Two have balanced translocations that disrupt NFIA. A third individual two half-siblings an...
β-lactam allergy skin testing (BLAST) is recommended by antimicrobial stewardship program (ASP) guidelines, yet few studies have systematically evaluated its impact when delivered at point of care. We conducted a pragmatic multicenter prospective evaluation the use point-of-care BLAST ASPs. In staggered 3-month intervals, ASP teams 3 hospitals received training allergists to offer for eligible patients with infectious diseases receiving nonpreferred therapy due severity their reported...
Pseudoachondroplasia (PSACH) is an autosomal dominant dwarfing condition characterized by disproportionate short stature, joint laxity, and early-onset osteoarthrosis. PSACH caused mutations in the gene encoding cartilage oligomeric matrix protein (COMP). We are reporting on COMP 12 patients with PSACH, including ten novel mutations. Eleven of exons 17A, 17B, 18A, which encode calcium-binding domains, one mutation exon 19, encodes part carboxy-terminal globular domain. Two identified common...
Pseudoachondroplasia (PSACH) is a spondylo-epi-metaphyseal dysplasia characterized by disproportionate short stature, generalized ligamentous laxity, and precocious osteoarthritis. PSACH caused mutations in the cartilage oligomeric matrix protein (COMP) gene, which codes for non-collagenous expressed territorial of chondrocytes. Autosomal dominant inheritance has been demonstrated many families; however, autosomal recessive suggested some severe familial cases. Alternatively,...
35 Background: The inhibitor of apoptosis (IAP) protein Survivin and its splice variants are differentially expressed in breast cancer tissues have recently been shown to be released from tumor cells via small membrane-bound vesicles called exosomes. Tumor-derived exosomes play multiple roles growth metastasis may produce these functions by impacting immune escape, invasion angiogenesis. We, therefore, hypothesize that analysis exosomal provide a novel biomarker for early diagnosis addition...
Abstract This essay addresses the revival of culturalist assumptions in historical archival studies and suggests an alternative framework. Rather than provenance, it privileges textual circulation; rather civilizational divides between supposedly distinct “European” “Islamic” archivalities, highlights mutability commensurability as defining elements a broadly shared, if inherently dynamic, internally complex, transactionally defined early modern archivality. We first show how historiography...
Abstract These concluding reflections assess how the contributors to this special issue intervene in key assumptions that shape current field of archival studies. As “archival turn” gains ground, forms Euro- and state-centrism reappear scholarship otherwise innovative its attention textual remnants past. Here, instead, we explore methodological stakes involved defining both “archive” historical power brokers who created preserved a documentary record pursuit their varied social, cultural,...