- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Gastroesophageal reflux and treatments
- Peptidase Inhibition and Analysis
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Endoplasmic Reticulum Stress and Disease
- Phytase and its Applications
- Protein Hydrolysis and Bioactive Peptides
- Pancreatic and Hepatic Oncology Research
- Lymphoma Diagnosis and Treatment
- Abdominal vascular conditions and treatments
- Mycobacterium research and diagnosis
- Chronic Kidney Disease and Diabetes
- GDF15 and Related Biomarkers
- Potassium and Related Disorders
- Protease and Inhibitor Mechanisms
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Colorectal Cancer Screening and Detection
- Cytomegalovirus and herpesvirus research
- Chronic Lymphocytic Leukemia Research
- Esophageal and GI Pathology
Hospital Dr. Nélio Mendonça
2017-2021
Instituto Português de Oncologia Francisco Gentil
2021
Hepatosplenic T-cell lymphoma (HSTCL) is an extremely rare and aggressive form of non-Hodgkin associated with poor response to treatment high mortality. There increased incidence among patients inflammatory bowel disease, especially young male under 35 years old on combination therapy (thiopurine anti-TNF-α). We describe a case HSTCL in patient stenosing ileal Crohn's disease azathioprine monotherapy for 4.8 admitted our hospital intra- abdominal sepsis. Despite chemotherapy, the eventually...
Introduction: Although most cases of colon ischemia (CI) are mild and self-limiting, when severe it implies high mortality rates. We aimed to evaluate the risk predictive value classification proposed by American College Gastroenterology (ACG) guidelines (2015), created provide a management algorithm. Methods: A retrospective multicenter study was conducted on adult patients with definite CI (clinical, endoscopic, pathologic culture criteria), between 2013 2016. Data collected clinical...
Esophageal and gastroduodenal necrosis are rare conditions with poor prognosis. We describe a case that was diagnosed upper endoscopy in the setting of severe septic shock. To our knowledge, this is first which esophageal occurred simultaneously setting. discuss pathophysiology, diagnostic approach, treatment options entity.
Cytomegalovirus (CMV) infection in ulcerative colitis (UC) is common during relapses however true CMV rare. It poses as a clinical challenge since no optimal method for relevant has been determined even though current recommendations agree on histology/immunohistochemistry (IHQ). However these parameters require extensive biopsies diagnosis and are not readily available most centres. Therefore based decision seems peremptory. Clinical, laboratory, endoscopic, pathological data of patients...
A 42-year-old female patient was referred to our gastroenterology department with a 4-month history of weekly symptoms dysphagia for solids and liquids. The also reported occasional food impaction heartburn. She denied nausea, vomiting, weight loss or recent change in bowel habits. not under any medication. Medical surgical unremarkable. There no family gastrointestinal cancer. Physical examination normal, laboratory tests did reveal anaemia other abnormalities. underwent an...
Die Pi*Z-Mutation im SERPINA1 Gen führt zur Akkumulation von abnormalem Alpha-1-Antitrypsin (AAT) in Hepatozyten. Dies zu Einschlusskörpern und proteotoxischem Stress. heterozygote Variante (Pi*MZ) stellt einen wichtigen Risikofaktor für die Entwicklung einer Leberzirrhose bei Individuen mit vorbestehenden Lebererkrankung dar. Um ihren Stellenwert der Gesamtpopulation klären, haben wir Pi*MZ-Individuen Trägern homozygoten (Pi*ZZ), jeweils ohne vorbestehende Lebererkrankung, verglichen.
A 51-year-old man was referred to our institution for removal of a large semipedunculated polyp (0-Isp) involving the appendiceal orifice ([Fig. 1]). Previous biopsies showed tubulovillous adenoma (TVA) with high grade dysplasia (HGD). Endoscopic resection under general anesthesia in operating room proposed and agreed by patient. 30-mm 0-Isp lesion extending into appendix (> 75 % orifice) found, narrowband imaging showing regular mucosal pattern without areas suggestive deep invasion....