About
Contact & Profiles
A5061613760
Research Areas
- SARS-CoV-2 and COVID-19 Research
- Advancements in Semiconductor Devices and Circuit Design
- Vaccine Coverage and Hesitancy
- Immunotherapy and Immune Responses
- Bacteriophages and microbial interactions
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
Academy of Military Medical Sciences
2023
Beijing Fengtai Hospital
2021
Aluminum (alum) adjuvant is the most extensively used protein subunit vaccine adjuvant, and its effectiveness safety have been widely recognized. The surface charge of antigen determines electrostatic adsorption to alum which directly affects immune efficacy vaccine. In our study, we precisely modified by inserting charged amino acids into flexible region SARS-CoV-2 receptor-binding domain (RBD), achieving a site-specific anchor between immunogen adjuvant. This innovative strategy extended...
10.1016/j.xinn.2023.100451
article
EN
cc-by-nc-nd
The Innovation
2023-05-29
10.1007/s11684-023-1034-6
article
EN
Frontiers of Medicine
2023-12-01
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