A5088340407- COVID-19 and healthcare impacts
- Prostate Cancer Treatment and Research
- Breast Cancer Treatment Studies
- Cancer survivorship and care
- Advanced Radiotherapy Techniques
- Oral and Maxillofacial Pathology
- Medical Imaging Techniques and Applications
- Frailty in Older Adults
- Prostate Cancer Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Radiation Dose and Imaging
- Advances in Oncology and Radiotherapy
- Head and Neck Surgical Oncology
- Cancer Immunotherapy and Biomarkers
- Cancer Risks and Factors
- Full-Duplex Wireless Communications
- Hydrogen's biological and therapeutic effects
- Nonmelanoma Skin Cancer Studies
- Sarcoma Diagnosis and Treatment
- Polyomavirus and related diseases
- CCD and CMOS Imaging Sensors
- Meningioma and schwannoma management
- Colorectal and Anal Carcinomas
- Nutrition and Health in Aging
- Colorectal Cancer Treatments and Studies
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2015-2022
Azienda Ospedaliero Universitaria Maggiore della Carita
2015-2022
Azienda Ospedaliera Ospedale Maggiore
2021
March of Dimes
2018
University of Bologna
2018
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2006-2010
The purpose of this study was to determine the effect hospital volume on long-term survival for women with breast cancer.Survival analysis and proportional-hazard modeling were used assess 5-year risk death, adjusting clinical sociodemographic variables.At 5 years, patients from very low-volume hospitals had a 60% greater all-cause mortality than high-volume hospitals.Hospital cancer surgical cases has strong positive survival. Research is needed identify whether processes care, especially...
Background. Docetaxel (DTX) and zoledronic acid (ZOL) are effective in patients with hormone resistant prostate cancer (HRPC) bone metastases. A phase I clinical trial of metronomic administration Zoledronic Acid ANd TaxoterE combination (ZANTE trial) 2 different sequences was conducted HRPC. Patients methods. Twenty-two enrolled into the study (median age: 73 years; range: 43-80) received one three escalated doses DTX (30, 40 50mg/m2) a fixed dose ZOL (2mg), both administered every 14 days...
We report on the early clinical outcomes of a prospective series breast cancer (EBC) patients treated with ultra-hypofractionated post-operative whole-breast irradiation (WBI) after breast-conserving surgery (BCS) and axillary management. Primary endpoints were patient's compliance acute toxicity. Secondary included physician-rated cosmesis ipsilateral tumour recurrence (IBTR). Acute toxicity was evaluated at end WBI, 3 weeks 6 months thereafter, according to Common Terminology Criteria for...
[18F] fluorodeoxyglucose positron emission tomography/computed tomography ([18F] FDG-PET/CT) is used for diagnosis, staging, response assessment and prognosis prediction in different tumors, but its role esophageal cancer still debated. The aim of this study was to evaluate the semiquantitative baseline PET parameters as possible prognostic predictive factors a series carcinomas treated with combined modalities.43 patients carcinoma were chemoradiotherapy (CRT) followed by surgery 20 cases...
Abstract Background Age is considered as one of the most important risk-factor for many types solid and hematological cancers, their incidence increases with age in parallel to ever-growing elderly population. Moreover, cancer constantly increasing a consequence increase life expectancy that favors process cellular senescence. Geriatric assessment has been increasingly recognized predictive prognostic instrument detect frailty older adults cancer. In particular, G8 score simple reproducible...
Normal tissue radiosensitivity is thought to be influenced by an individual’s genetic background. However, the specific variants underlying risk of late skin reactions following radiotherapy for breast cancer remain elusive. To unravel basis radiation-induced toxicity, we carried out targeted next-generation sequencing germline DNA samples from 48 patients with extreme toxicity phenotypes, consisting 24 cases grade 2–3 subcutaneous fibrosis and/or telangiectasia (LENT-SOMA scales) and...
In COVID-19 pandemic, cancer patients may be vulnerable for their immunological status and need of immunosuppressive anti-neoplastic treatments. Choosing the best treatment option in positive is still a challenging issue. We report case 62-year-old woman diagnosed with multiple myeloma affected by COVID-19. After diagnosis January 2019, patient underwent first line therapy followed bone marrow autologous stem cell transplantation, achieving complete response September 2019. March 2020,...
12038 Background: Elderly cancer patients may have important benefits from innovative treatments. However, they are often barred clinical trials because of highly selective eligibility criteria, or due to biased and subjective physician standpoints including reluctance invite elderly fear excessive toxicity. Indeed, geriatric assessment has been increasingly recognized as predictive prognostic instrument detect frailty in older adults with cancer. In this perspective, the G8 score is a...
Conclusions: CT guided high dose brachytherapy can be successfully implemented in a cancer centre achieving good levels of local control and overall survival.Node positivity on original MRI is predictive for recurrence.A complete response week 5 predicts excellent long term pelvic control.
S842ESTRO 37Therefore, a systematic review on acute and late toxicity after postoperative HFRT was performed.Even outcome data in terms of local control (LC), overall survival (OS), biochemical relapse-free (bRFS) were analyzed. Material MethodsA search based PRISMA methodology performed using PubMed.Only studies published English reporting clinical results (toxicity outcome) adjuvant or salvage included. ResultsA total 1205 patients from 17 eligible included.These retrospective (7)...
Abstract Background: Increasing evidence suggests a link between T-cell senescence and tumour prognosis. In particular, high levels of circulating senescent T-lymphocytes have been also correlated with worse response to anti-cancer treatments. this perspective, therapeutic approach aimed at clearance restoring is regarded as an innovative strategy in cancer treatment currently under investigation pre-clinical clinical models. The purpose the present study characterize impact predictive...