A5025770046- Luminescence Properties of Advanced Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Glass properties and applications
- Computational Drug Discovery Methods
- Polyoxometalates: Synthesis and Applications
- Solid State Laser Technologies
- Machine Learning in Materials Science
- Complexity and Algorithms in Graphs
- Photonic and Optical Devices
- Luminescence and Fluorescent Materials
- Catalytic C–H Functionalization Methods
- Advanced Graph Theory Research
- Optical Network Technologies
- Organic Light-Emitting Diodes Research
- Laser-induced spectroscopy and plasma
- Photonic Crystal and Fiber Optics
- Advanced Photonic Communication Systems
- Advanced Fiber Optic Sensors
- Protein Structure and Dynamics
- EEG and Brain-Computer Interfaces
- Advanced Fiber Laser Technologies
- Gas Sensing Nanomaterials and Sensors
- Conducting polymers and applications
- Photonic Crystals and Applications
- Cyclopropane Reaction Mechanisms
Hangzhou Dianzi University
2025
National University of Defense Technology
2023-2025
Shandong University
2024
University of Chinese Academy of Sciences
2014-2024
Chinese Academy of Sciences
2013-2024
Wuhan National Laboratory for Optoelectronics
2012-2024
University of Technology Sydney
2024
Hong Kong Polytechnic University
2023-2024
Nanyang Technological University
2024
Peng Cheng Laboratory
2024
Abstract Structure-based generative chemistry is essential in computer-aided drug discovery by exploring a vast chemical space to design ligands with high binding affinity for targets. However, traditional silico methods are limited computational inefficiency, while machine learning approaches face bottlenecks due auto-regressive sampling. To address these concerns, we have developed conditional deep model, PMDM, 3D molecule generation fitting specified PMDM consists of equivariant diffusion...
This tutorial review provides a comprehensive and authoritative summary on the exciting research activities in fields of poly(ionic liquid)s (PILs), covering their synthesis applications number areas.
The preparation of ordered metal organic frameworks (MOFs) will be a critical process for MOF-based nanoelectrodes in the future. In this work, we develop novel approach to fabricating type MOF electrode based on flexible amino-functionalized graphene paper modified with 2D oriented assembly Cu3(btc)2 nanocubes via facile interfacial synthesis and an effective dip-coating method. One interesting finding is that arrays at oil-water interfaces can transferred paper, leading densely packed...
Abstract Motivation Retrosynthesis is a critical task in drug discovery, aimed at finding viable pathway for synthesizing given target molecule. Many existing approaches frame this as graph-generating problem. Specifically, these methods first identify the reaction center, and break targeted molecule accordingly to generate synthons. Reactants are generated by either adding atoms sequentially synthon graphs or directly appropriate leaving groups. However, both of strategies have limitations....
A high-efficiency and pure white OLED has been realized by only doping one novel phosphorescent orange-light-emitting complex (bzq)2Ir(dipba) into a suitable deep-blue-emitting fluorescent Bepp2 as an emissive layer. The highest efficiency for OLEDs with simple HTL-EML-ETL architecture, peak power (PE) of 48.8 lm W−1 external quantum (EQE) 27.8%, employing both singlet triplet excitons emission. PE EQE at the applicable brightness 1000 cd m−2 are 37.5 36.8%, respectively.
The first organocatalytic asymmetric synthesis of a spirooxindole skeleton incorporated with cyclobutane moiety has been successfully developed on the basis H-bond-directing dienamine activation. Structurally complex spirocyclobutyl oxindoles, which possess four contiguous stereocenters, including one spiro quaternary center, were obtained in good yields (up to 83%) excellent β,γ-regioselectivity (>19:1) and stereocontrol >19:1 dr 97% ee).
Abstract Over the past decade, vinyldiazo compounds have provided mild, efficient, and highly selective methods for construction of heterocycles carbocycles. Dinitrogen extrusion with suitable catalysts provides carbon framework [3+ n ] cycloaddition a large variety dipolarophiles. This minireview, covering latest achievements in field metal‐catalyzed cyclization reactions reagents, focuses on reagent‐ or catalyst‐dependent chemodivergence: different reagents metal direct to pathways that...
An efficient method has been developed to identify meat species by using laser-induced breakdown spectroscopy (LIBS). To improve the accuracy and stability of identification, multiplicative scatter correction (MSC) was adopted first pretreat spectrum for scatter. Then corrected spectra were identified K-nearest neighbor (KNN) model. The results showed that identification rate improved from 94.17% 100% prediction coefficient variance (CV) decreased 5.16% 0.56%. This means MSC LIBS...
Selective CDK2 inhibitors have the potential to provide effective therapeutics for CDK2-dependent cancers and combating drug resistance due high cyclin E1 (CCNE1) expression intrinsically or CCNE1 amplification induced by treatment of CDK4/6 inhibitors. Generative models that take advantage deep learning are being increasingly integrated into early discovery hit identification lead optimization. Here we report a highly potent selective macrocyclic inhibitor QR-6401 (23) accelerated...
A multi-spectral-line calibration approach based on an artificial neural network is presented for steel analysis in LIBS.
Abstract The emergence of metal–organic frameworks (MOFs) has sparked intensive attention and opened up the possibility “crystal engineering.” However, low conductivity, slow diffusion guest molecules, as well powder forms always hinder development MOF application, especially for biosensors bioelectronics. Herein, a coffee ring–inspired strategy toward oriented self‐assembly biomimetic film following Murray's law is proposed, which can effectively reduce transfer resistance. approach...
Many natural organizations with some special functional properties possess fractal tissues which display nearly the same at every scale. The benefit of mimicking structure in synthetic materials warrants further exploration. To tackle this challenge, we assemble metal–organic frameworks (MOFs) into structures by using a bottom-up approach inspired from evaporation-driven crystallization. Such hierarchically branched MOFs exhibit unexpected performances electrochemistry, and can be versatile...
We propose a strip loaded amplifier employing SU-8 as the waveguide and nanoparticles (NPs)-polymethyl methacrylate (PMMA) cladding layer. By leveraging undoped waveguide, polymer accomplished remarkably low transmission losses, reaching 1.8 dB/cm at 1530 nm. prepared NPs-PMMA nanocomposite by utilizing NaLu 0.1 Y 0.7 F 4 : Er 3+ , Yb @NaLuF core-shell nanoparticles, which exhibited significantly enhanced lifetime of 6.15 ms. An internal net gain up to 17.7 dB was achieved on with length...
We report on a new kind of white light emitting glass suitable for long-wavelength ultraviolet excitation by simultaneously blue, green and red fluorescence, which is fabricated melting Ce(3+)-Tb(3+)-Mn(2+) co-doped borosilicate glass. The spectroscopic properties singly, doubly triply doped glasses have been reported the energy transfer from Ce(3+) to Tb(3+) Mn(2+) has also investigated. By adjusting concentration different co-dopants, we obtained ideal with color coordinate (x = 0.318, y 0.333).
Surface-supported metal-organic framework (MOF) films hold fantastic promises for viable scientific applications, particularly in sensors and electronic devices. However, slow diffusion, limited mass transfer, low conductivity hinder the industrial application of MOFs. Herein, we propose a rime-inspired MOF film based on kind beautiful natural landscape. To mimic rime architecture, compare conclude intrinsic similarity between biomineralization electrochemical self-assembly MOFs used an...
The main target of retrosynthesis is to recursively decompose desired molecules into available building blocks. Existing template-based methods follow a template selection stereotype and suffer from limited training templates, which prevents them discovering novel reactions. To overcome this limitation, we propose an innovative prediction framework that can compose templates beyond templates. As far as know, the first method uses machine learning reaction for prediction. Besides, effective...
A phosphorescent material (Fppy)2Ir(dipba) possessing high PL efficiency in the solid state and superior hole/electron transporting property has acted successfully as an efficient neat emitter well excellent host for high-performance PHOLEDs.
A new layered molybdenum cobalt phosphate, Na2[Co(H2O)6][(Mo16O32)Co16(PO4)4 (HPO4)16(H2PO4)4(OH)4(C10H8N2)4(C5H4N)2(H2O)6]·4H2O (1), has been hydrothermally synthesized and structurally characterized. 1 crystallizes in the monoclinic space group P21/n with a = 15.6825(18) Å, b 39.503(4) c 17.2763(17) β 93.791(2)°, V 10679.4(18) Å3, Z 2. polyoxoanion of exhibits an unusual organic−inorganic hybrid wheel-type cluster, which two pyridine ligands link to surface CoII atoms...
We have disclosed the photophysical and electroluminescent properties of a series hetero-annulated π-conjugated dithieno[3,2-b:2′,3′-d]metallole derivatives incorporating Ge, Si, P, S atoms as bridging center. The influence structures on their has been investigated systematically by UV/vis photoluminescence (PL) spectroscopy, transient PL measurements, DFT calculations. All these compounds show bright fluorescence with high quantum yields both in solutions doped thin films host matrix....
Dirhodium(II) catalyzed dinitrogen extrusion from diazocarbonyl compounds by 2,6-dichloropyridine-N-oxide forms ketocarbonyl in near-quantitative yields. Reactions occur at room temperature, and the pyridine product does not coordinate with dirhodium(II) to inhibit catalysis. Anhydrous tricarbonyl compounds, as well dicarbonyl are conveniently prepared this methodology, they have been used situ for catalytic ene aldol transformations.