- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
- Dental Implant Techniques and Outcomes
- Mesenchymal stem cell research
- Bone Tissue Engineering Materials
- Moringa oleifera research and applications
- Periodontal Regeneration and Treatments
- Diverse Scientific Research Studies
- Advanced Drug Delivery Systems
- Dental Research and COVID-19
- Endodontics and Root Canal Treatments
- Bone and Dental Protein Studies
- Forensic Anthropology and Bioarchaeology Studies
- Medicinal Plant Research
- Scientific and Engineering Research Topics
- AI in cancer detection
- Bee Products Chemical Analysis
- Oral and Maxillofacial Pathology
- Medicinal Plants and Neuroprotection
- Bone Metabolism and Diseases
- Pharmacology and Nanomedicine Research
- Medical Imaging and Analysis
- Dental materials and restorations
- Hibiscus Plant Research Studies
- dental development and anomalies
Airlangga University
2019-2025
The orthodontic mini-implant (OMI) failure often occurs due to the accumulation of peri-implantitis bacteria surrounding it, which results in a stable, resistant form absolute skeletal anchorage during treatment. Administering doxycycline may be solution, but long-term side effects result antibiotic resistance. Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, have potential as an OMI alternative therapy. This study investigates antibacterial activity...
Mangrove (Aegiceras corniculatum) is an abundant natural marine resource of Indonesia, which can be explored for treating periodontal disease due to its potential as immunoregulatory, antibacterial, and antioxidant properties. The objective this study was investigate the active compound from Indonesian mangrove leaf extract (A. (MLE) developing a herbal-based mouthwash through in silico vitro studies. Phytochemistry liquid chromatography-high resolution mass spectrometry (LC-HRMS) were done...
Context: The most common biomaterial used for dental implants is titanium. However, the release of metal ions and risk allergic reactions to metals that may occur in some patients cannot be avoided. Hydroxyapatite-polymethylmethacrylate (HA-PMMA) composite biomaterials are proposed have potential as implant due their mechanical, chemical, biological properties. HA-PMMA induce osseointegration, biocompatible, less reactions, no released. In addition, can obtained from Indonesia’s abundant...
Background/purpose: According to The Global Burden of Disease Study in 2016, oral health problems, especially periodontal disease, become the 11th most common globally, including dental cavities, and fungal infection. Epigallocatechin-3-gallate (EGCG), composition green tea, has excellent benefits plays a vital role health, regulating pathogenic bacteria activity that causes inflammation. Stem cells human exfoliated deciduous teeth (SHED) metabolites also have great play an essential sector,...
Introduction: Periodontopathogenic bacteria are Gram-negative anaerobic that often cause peri-implantitis such as Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Fusobacterium nucleatum. Objective: This study is to analyze the periodontopathogen antibacterial properties of Polymethylmethacrylate (PMMA) Hydroxyapatite (HA) composites against growth F. nucleatum, P. A. Actinomycetemcomitans in vitro. Materials Methods: Inhibition zone PMMA-HA periodontopathogenic was...
The roselle flower (Hibiscus sabdariffa) has shown potential as an alternative therapy for bone regeneration. This extract can induce osteoblast maturation, which is crucial forming new bone. study aim was to evaluate the viability of 7F2 preosteoblast cell line following application a nanoemulsion (RNE).This utilized assess (%). RNE oven-dried at 35 40°C 6 hours, resulting in solid extract. then diluted into different concentrations. preparation 1% stirred 1,400 rpm 50°C 90 minutes. Primary...
the Moringa oleifera leaf (MO) has active compounds that may be beneficial for peri-implantitis therapy. This research aims to analyze phytochemical, antioxidant, and antibacterial properties of L. nanosuspension (MON) extract in peri-implantitis-related bacteria. MON phytochemical analysis was conducted examine such as flavonoids, saponins, quinones, alkaloids, tannins, terpenoids, steroids. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay antioxidant capacity evaluated, gas...
The gingival medicinal signaling cells conditioned medium (GMSCs-CM) is a biocompatible material which possessed beneficial cytokine, anti-microbial peptide, growth factor that can be collected after culture. GMSCs- CM may inhibit bone resorption in order to improve the patient’s quality of life. In this study, potential effect GMSCs-CM on number osteoclasts and osteoblasts Lipopolysaccharide (LPS)-induced calvaria wistar rats (Rattus novergicus) has been analyzed. Twenty-eight male healthy...
This study was aimed to investigate RGCBE extract as antioxidant and anti-peri-implantitis bacteria through in vitro its potential antioxidant, antibacterial, anti-inflammatory, antibone resorption, proosteogenic silico study.AND METHODS: Absorption, distribution, metabolism, excretion toxicity prediction, molecular docking simulation, visualization of chlorogenic acid (CGA) coumaric (CA) antibacterial were investigated silico. Inhibition zone by diffusion method, minimum inhibitory...
Abstract Objectives The aim of this study was to describe the process regeneration damaged salivary glands due ionizing radiations by bone marrow mesenchymal stem cells (BM-MSCs) transplantation that have been given hypoxic preconditioning with 1% O2 concentration. Materials and Methods Stem cell culture performed under normoxic (O2: 21%) conditions incubating for 48 hours in a low oxygen tension chamber consisting 95% N2, 5% CO2, O2. Thirty male Wistar rats were divided into four groups:...
Context: Oral manifestations that arose from COVID-19 infection often causes morbidity and systemic drug administration is less effective. Roselle flower (Hibiscus sabdariffa) one of the plants used in infusion as it gives health benefits. Hence, H. sabdariffa may benefit adjuvant therapy to treat oral manifestation due COVID-19. Aims: To investigate potential anthocyanins, tartaric acid, ascorbic acid chemical compounds antiviral, anti-inflammatory, antioxidant, increasing tissue...
Produced by a stingless bee (Tetragonula biroi) from Sulawesi Island, propolis is an active compound that requires further studies to determine its herbal-based medicinal applications. In addition, well known as potential natural ingredient for herbal medicine with minimal side effects. The honeybee, native Sulawesi, produces propolis, resin. Propolis Trigona bees in has the highest flavonoid content compared Apis mellifera bees. Flavonoids are most common compounds contained propolis. may...
Bone is a dynamic tissue that undergoes remodeling. During bone remodeling, there are transcription factors such as nuclear factor-activated T cells-1 (NFATc1), sclerostin, and tartrate-resistant acid phosphatase (TRAP) released for resorption. Metabolite from gingival mesenchymal stem cells (GMSCs) has the ability to activate proliferation, migration, immunomodulation, regeneration of tissues. Furthermore, aim this study investigate metabolite GMSCs' effect on expression NFATc1, TRAP,...
Background: Radiography is essential in dentistry for diagnosis and treatment planning, with two-dimensional imaging such as panoramic periapical radiographs being commonly used. The advancement to three-dimensional imaging, specifically Cone Beam Computed Tomography (CBCT), provides more detailed visualization but remains underutilized due limited availability knowledge among dentists Indonesia. Purpose: This research aimed determine the experience of using 2D 3D diagnostic Surabaya....
The loss of bone mineral density (BMD) in various sites the body, including mandible, is main sign osteoporosis. Thus, computer-aided diagnosis (CAD) system was developed for assessment and patients were classified into normal, osteopenia, osteoporosis groups using a digital panoramic radiograph. Data dental radiographs corresponding BMD assessments from 123 postmenopausal women collected. For proposed CAD test, regions interest (ROI) that located below left right mental foramen on...
The arrival of a pneumonia disease with severe acute respiratory syndrome called COVID-19 has taken the world by storm. It is presence made researchers and World Health Organization (WHO) continue to try find right clinical management protocol deal this pandemic. use convalescent plasma, which been around for long time, discussed recently. Convalescent plasma (CP) therapy classic adaptive immunotherapy that applied in prevention treatment infectious diseases more than century used previously...
Abstract Foreign objects lodged in the mandibular bone often result from trauma or dental procedures. Accurate localization of these foreign is crucial for guided surgical removal, especially when patients present with persistent pain. Conventional imaging modalities like periapical and panoramic radiographs may not provide sufficient detail precise localization. Cone beam computed tomography (CBCT) has emerged as a valuable tool interventions owing to its superior capabilities. We two cases...
Radiation is any kind of energy transmitted without an intermediate medium. Radiant generally wave-shaped, most commonly sinusoidal. There are two types radiation: ionizing radiation and non-ionizing radiation. Ionizing that causes the process ejecting electrons from atoms to form ion pairs. Attention should be paid radiation, particularly its sources, types, properties, effects, methods avoidance. well known, for example X-rays. Non-ionizing can occur in equipment mobile phones. Miftaful...
Background: Dental peri-implantitis is an inflammation that occurs in the peri-implant soft tissue and accompanied by bone resorption, decreased osseointegration, pockets. Graptophyllum pictum L. Griff extract may act as complementary therapy for peri-implantitis. Objectives: To investigate effectiveness of G. a Materials Methods: A phytochemical test was performed to determine active compounds using each compound's reagents. Antioxidant assay examine antioxidant activity compared with...