A5052185270- Phytochemistry and Biological Activities
- Plant and Fungal Species Descriptions
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Genomics and Phylogenetic Studies
- Ginger and Zingiberaceae research
- Remote Sensing and Land Use
- Forest, Soil, and Plant Ecology in China
- Phytochemistry and Bioactive Compounds
- Plant Virus Research Studies
- Plant Diversity and Evolution
- Analytical Chemistry and Chromatography
- Nephrotoxicity and Medicinal Plants
- Plant Pathogens and Fungal Diseases
- Ginseng Biological Effects and Applications
- Biological and pharmacological studies of plants
- Geology and Paleoclimatology Research
- Ion channel regulation and function
- Photosynthetic Processes and Mechanisms
- Quality and Safety in Healthcare
- Phagocytosis and Immune Regulation
- Protein Tyrosine Phosphatases
- Plant Ecology and Taxonomy Studies
- Fern and Epiphyte Biology
- Protein Kinase Regulation and GTPase Signaling
First Affiliated Hospital of Xinxiang Medical University
2025
Shanghai University of Traditional Chinese Medicine
2010-2024
Hunan Agricultural University
2021
Nanjing Agricultural University
2020
Wuhan University
2017
Shanghai University
2012-2015
Hong Kong Baptist University
2014
Northwest A&F University
2013
Chinese PLA General Hospital
2013
Northwest Research Institute of Chemical Industry
2007-2010
Immune evasion is a hallmark feature of cancer, and it plays an important role in tumour initiation progression. In addition, immune severely hampers the desired antitumour effect multiple cancers. this study, we aimed to investigate Notch pathway head neck squamous cell carcinoma (HNSCC) microenvironment. We first demonstrated that Notch1 signaling was activated Tgfbr1/Pten-knockout HNSCC mouse model. inhibition using γ-secretase inhibitor (GSI-IX, DAPT) decreased burden model after...
Abstract Tumor metastasis is the predominant cause of lethality in cancer. We found that Neobractatin (NBT), a natural compound isolated from Garcinia bracteata , could efficiently inhibit breast and lung cancer cells metastasis. However, mechanisms NBT inhibiting remain unclear. Based on RNA-sequencing result transcriptome analysis, Muscleblind-like 2 (MBNL2) was to be significantly upregulated treated with NBT. The Cancer Genome Atlas (TCGA) database analysis indicated expression MBNL2...
Scrophularia dentata is an important Tibetan medicinal plant and traditionally used for the treatment of exanthema fever in Traditional Medicine (TTM). However, there little sequence genomic information available S. dentata. In this paper, we report complete chloroplast genome it first sequenced member Sect. Tomiophyllum within (Scrophulariaceae). The gene order organization are similar to other Lamiales genomes. plastome 152,553 bp length includes a pair inverted repeats (IRs) 25,523 that...
The breakpoint cluster region gene product (Bcr) is a GTPase-activating protein (GAP) for members of the Rho family, Cdc42Hs, and Rac1, as brain n-chimaerin. At least 15 proteins have sequence identity to GAP domain (150 amino acid residues) Bcr. widespread occurrence that possess Bcr-related makes it especially important understand its structure/function relationships. Amino alignment these reveals three blocks conservation in domain. Here, we present mutational analysis this using...
The Himalaya-Hengduan Mountain region is one of the hotspots biodiversity research. uplift Qinghai-Tibetan Plateau (QTP) and Quaternary glaciation caused great environmental changes in this region, responses many species QTP to climate are still largely unknown. genetic structure phylogeographical history
Dry rhizome of Dryopteris crassirhizoma Nakai (Dryopteridaceae), also known as Guan Zhong, is a traditional Chinese herbal medicine used in the treatment viral disease. But dry rhizomes Woodwardia japonica (L. f.) Sm., Osmunda Thunb. and Cyrtomium fortunei J. Sm. are Zhong local areas. The adulterants similar to crassirhizoma. It difficult identify botanical origin these herbs. In our study, sequences cpDNA rbcL gene were determined analyzed for adulterant species, where nineteen molecular...
Sustainable agriculture requires effective and safe biofertilizers biofungicides with low environmental impact. Natural ecosystems that closely resemble the conditions of biosaline may present a reservoir for fungal strains can be used as novel bioeffectors.
ABSTRACT Yunaconitine (YAC) is a toxic aconite alkaloid that considered to be hidden poison since it frequently found in body fluids from poisoning patients, but has not been well studied commonly used herbal drugs. In this paper, rapid and sensitive ultra high‐performance liquid chromatography–tandem mass spectrometry (UHPLC‐MS/MS) detection combined with microwave‐assisted extraction (MAE) was developed for high throughput simultaneous determination of YAC six other alkaloids 31 samples...
We studied the efficiency of maintaining and restoring cytoplasmic male sterility (CMS) systems in pepper (Capsicum annuum L.).An Rf-linked molecular marker was employed to analyze interaction between 6 CMS lines (A), 5 maintainers (B), restorers (C).Sterility maintained matings 201A x 200B, 203A 206A 200A 201B, 202B, 203B, 206B, 206B.All restored fertility 200A, 202A, 203A, 204A, except that 213C could not restore 204A.However, had diverse abilities individual lines.The amplified by PCR...
A liquid chromatography-electrospray ionization-ion-trap mass spectrometry (MSn ) method was established and applied for authentication of Gentiana straminea from the four substitutes, G. tibetica, lhassica, waltonii robusta, based on chemical profiling principal iridoid glucosides aided by a quadrupole time-of-flight spectrometry. The fragmentation pathways three representative glucosides, loganic acid, gentiopicroside sweroside, were investigated MSn analysis in negative ion mode, which...
Abstract Gentiana straminea Maxim. is a perennial herb and mainly distributed in the Qinghai-Tibetan Plateau. To adapt to extreme environment, it has developed particular morphological, physiological, genetic structures. Also, rich iridoids, one of original plants traditional Chinese ‘Qinjiao’. Herein, we present its first chromosome-level genome sequence assembly compare with genomes other species facilitate analysis genomic characteristics. The assembled size G. was 1.25 Gb, contig N50 7.5...
This study aims to establish a new method for quality evaluation of Gentianae Macrophyllae Radix by simultaneous determination five iridoids (loganic acid, 6'-O-beta-D-glucopyranosylgentiopicroside, swertiamarin, gentiopicroside, sweroside), and detect in the root eight species (Gentiana macrophylla, G. straminea, crassicaulis, dahurica, robusta, waltonii, lhassica, tibetica). The separation was carried out on Shiseido SPOLAR C18 (4.6 mm x 250 mm, 5 microm) column eluted with mobile phase...
The alpine plant Gentiana robusta is an endemic species to the Sino-Himalayan subregion. Also, it one of original plants used as traditional Tibetan medicine Jie-Ji. We sequence nuclear ribosomal internal transcribed spacer (ITS) regions, matK, rbcL, rpoC1, trnL (UAA), psbA-trnH, atpB-rbcL, trnS( GCU)-trnG(UCC), rpl20-rps12, trnL(UAA)-trnF( GAA) fragments cp DNA in both G. and such relative straminea, crassicaulis waltonii. With Halenia elliptica outgroup, molecular systematic analysis...
Background Accurate identification of Chinese herbal medicines is the basis for their research and utilization. Molecular can effectively differentiate original plants from counterfeit plants. The quality genomic DNA an important factor affecting molecular identification. However, processing lead to degradation medicines, which make it difficult Objectives To establish a model Gentiana crassicaulis Radix evaluate effects methods storage times on integrity. Materials Methods A G....
Abstract The legume plant alfalfa ( Medicago sativa L.) is a widely cultivated perennial forage due to its high protein content, palatability, and strong adaptability diverse agro-ecological zones. Alfalfa self-incompatible cross-pollinated autotetraploid species with tetrasomic inheritance. Therefore, maintaining excellent traits through seed reproduction prime challenge in alfalfa. However, the cutting propagation technology could enable consistent multiplication of quality plants that are...