A5002857445- Global Cancer Incidence and Screening
- Health Systems, Economic Evaluations, Quality of Life
- Esophageal Cancer Research and Treatment
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Screening and Detection
- Prenatal Screening and Diagnostics
- RNA modifications and cancer
- Esophageal and GI Pathology
- Multiple and Secondary Primary Cancers
- Frailty in Older Adults
- Cancer-related molecular mechanisms research
- Anesthesia and Pain Management
- Circular RNAs in diseases
- Cancer Risks and Factors
- Gastric Cancer Management and Outcomes
- Genomic variations and chromosomal abnormalities
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Medical Research and Treatments
- Lung Cancer Treatments and Mutations
- Consumer Attitudes and Food Labeling
- Congenital heart defects research
- Ear Surgery and Otitis Media
- Regional Economics and Spatial Analysis
- Mycobacterium research and diagnosis
Guangdong Province Women and Children Hospital
2011-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Zhejiang Cancer Hospital
2022-2025
Third People 's Hospital of Chongqing
2025
Chongqing Maternal and Child Health Hospital
2025
Fujian University of Traditional Chinese Medicine
2025
Binzhou University
2024
Chinese Academy of Sciences
2024
Jiangsu University
2020-2024
Affiliated Hospital of Jiangsu University
2020-2024
Abstract Background ALG8-congenital disorder of glycosylation (ALG8-CDG) is a rare inherited metabolic leading to severe multisystem manifestations, with no reported prenatal patients date. Methods We describe two fetuses from single family ALG8-CDG presenting hydrops, undergoing comprehensive ultrasound, umbilical cord blood biochemistry, autopsy, placental pathology, and genetic testing. Results Prenatal ultrasound revealed fetal skeletal anomalies, cardiac developmental abnormalities,...
Lupus nephritis (LN) is a multifactorial autoimmune inflammatory disorder, with podocyte dysfunction or structural abnormalities playing pivotal role in its pathogenesis. Eucalyptus leaves, traditionally employed folk medicine, have demonstrated notable efficacy managing non-infectious inflammations. Eucarbwenstols D (R14) novel phloroglucinol-terpene that has been isolated from robusta. To further refine potential targets, we utilized an AI scoring system and successfully identified the...
Over the last decade, a few studies have investigated possible adverse effects of ambient air pollution on preterm birth. However, correlation between them still remains unclear, due to insufficient evidences.The and birth in Guangzhou city was examined by using Generalized Additive Model (GAM) extended Poisson regression model which we controlled confounding factors such as meteorological factors, time trends, weather day week (DOW). We also adjusted co linearity pollutants Principal...
The Chinese herbal compound Heshouwuyin has been shown to downregulate the apoptotic rate of testicular tissue cells in Wistar naturally aging rats, and this effect might be related mitochondrial pathway [15]. Apoptotic protease activating factor-1 (Apaf-1) is a major component complex, which key element endogenous [13]. To further clarify mechanism pathway, study used Apaf-1 as target explore by inhibits spermatogenic cell apoptosis.In study, an model rat was established using free radical...
Background: Increasing attention has been devoted to cancer screening and microbiota in recent decades, but currently there is less focus on characterization among screeners its relationship anxiety depression. Methods: We characterized the microbial communities of fecal samples collected through FOBT card from depression paired controls Henan, China (1:2, N = 69). DNA was extracted using MOBIO PowerSoil kit. The V4 region 16S rRNA gene sequenced MiniSeq processed QIIME1. LEfSe used identify...
Introduction Adult Polyglucosan Body Disease (APBD) is a rare, autosomal recessive neurodegenerative disorder that affects both the central and peripheral nervous systems. It primarily caused by mutations in Glycogen Branching Enzyme 1 ( GBE 1) gene. APBD typically associated with Ashkenazi Jewish populations, though it can occur other ethnic groups. This study aims to expand phenotypic genetic spectrum of APBD, particularly non-Ashkenazi patients, identify atypical alterations linked...
Abstract Background: Most studies have evaluated disability-adjusted life years (DALYs) of colorectal cancer (CRC) patients based on a set generic disability weights (DWs). This study aimed to apply local CRC-stage-specific DWs estimate the burden DALYs for CRC (CRC-DALYs) in populations China and consider influence screening coverage CRC. Methods: A prevalence-based model was constructed using data from various sources. Years lived with (YLDs) were estimated mainly via cumulative prevalence...
Esophageal cancer (EC) remains a global health challenge due to its poor prognosis. China and the United States of America (USA) represent two distinct epicenters EC burden. Understanding disparities in these countries is vital for tailoring prevention strategies, optimizing treatment, enhancing outcomes both countries. Yet, there lacks comprehensive comparison characteristics between In this multicenter, retrospective hospital-based study, we enrolled primary patients who received their...
American ginseng (Panax quinquefolius L.) is an important herb that cultivated in China, North American, and South Korea. It propagated from seed, but the seed has deep dormancy characteristics described as morphophysiological dormancy. Two-stage temperature stratification, a warm (15–20°C) cold (2°C) stratification period of 6 months, been used successfully for release. However, little known about molecular mechanisms release process. In this study, development after pollination process...
We aimed to obtain a set of health state utility scores patients with esophageal cancer (EC) and precancerous lesions in China, explore the influencing factors health-related quality life (HRQoL).A hospital-based multicenter cross-sectional study was conducted. From 2013 2014, EC or were enrolled. HRQoL assessed using European life-5 dimension (EQ-5D-3L) instrument. Multivariable linear regression analysis performed EQ-5D scores.A total 2090 156 precancer included study. The pain/discomfort...
Abstract In this work, high‐resolution flexible micro‐organic light‐emitting diodes (micro‐OLEDs) are presented by template‐directed growth. The templates prepared parallel patterning techniques (nanotransfer printing and photolithography) to create prepatterns on substrates. act as nucleation sites induce area‐selective growth of organic semiconductor molecules upon deposition. By optimization parameters such substrate temperature rate, uniform patterns diverse materials can be realized...
Objectives Hepatitis B virus (HBV) infection is a global public health threat, and couples of reproductive age comprise key population in aiming to reduce both the vertical horizontal transmission HBV. We aimed update knowledge on seroepidemiology status HBV Guangdong, China among large number planning conception, identify high-risk subgroups. Design A cross-sectional study was performed from 2014 2017. Setting The data were collected 641 642 (1 283 284 individuals) participating National...
Background: Increasing circular RNAs (circRNAs) are reported to participate in cancer progression. Nonetheless, the role of circRNAs nasopharyngeal carcinoma (NPC) has not been fully clarified. This work is aimed probe circ_0000215 NPC. Methods: Circ_0000215 expression NPC tissues and cell lines was examined by quantitative real-time polymerase chain reaction (qRT-PCR). Cell counting kit-8 (CCK-8) assay, 5-bromo-2'-deoxyuridine (BrdU) scratch healing assay Transwell experiment were executed...
We previously analyzed the expression of genes associated with Paris polyphylla var. yunnanensis seed maturation and dormancy release; however, we were unable to clarify relationship between gene levels these processes. To reveal molecular mechanisms underlying P. release during a warm stratification, transcriptomes dormant germinating seeds separately by RNA sequencing also compared stem-leaf root tissues harvested stage. The five generated 234,331 unigenes, which 10,137 (4.33%)...
Limitations in understanding the mechanism of transcriptional regulation by insulin are due part to lack models which there is insulin-responsive binding nuclear factors critical promoter regions.The insulin-like growth factor I (IGF-I) gene responds diabetes status via a footprinted sequence, region V, contains an AT-rich element and GC-rich site.We tested hypothesis that regulates site.Gel shift analysis with liver extracts V probe showed Sp1, Sp3, B 1 , persisted despite presence...
BACKGROUND: Effective regional analgesia during open surgery could reduce opioid consumption and enhance early recovery. We compared the effects of newly developed quadratus lumborum block (QLB) traditional epidural (EB) in uterine surgery.METHODS: In this randomized controlled trial, we included patients scheduled for elective May - September 30, 2019. Patients received QLB or EB perioperative pain relief before general anesthesia. Perioperative consumption, numeric rating scale (NRS: 0-10)...
Regarding whether a polycentric urban spatial structure is sustainable development model, various studies use different employment center identification methods, resulting in inconsistent conclusions. This paper takes Hangzhou, Wuhan, and Nanning, three Chinese cities at stages of as cases, adopts methods to identify centers compares the differences from morphological functional dimensions, puts forward multi-dimensional perspective for analyzing characteristics structure. The results show...