A5100626961- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Insect Resistance and Genetics
- Invertebrate Immune Response Mechanisms
- Livestock and Poultry Management
- Neurobiology and Insect Physiology Research
- Viral Infectious Diseases and Gene Expression in Insects
- Silk-based biomaterials and applications
- Advanced biosensing and bioanalysis techniques
- Studies on Chitinases and Chitosanases
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Insect-Plant Interactions and Control
- Rice Cultivation and Yield Improvement
- Antibiotic Resistance in Bacteria
- RNA Research and Splicing
- Orthoptera Research and Taxonomy
- Microbial Metabolic Engineering and Bioproduction
- GABA and Rice Research
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Nitrogen and Sulfur Effects on Brassica
- Genetics and Plant Breeding
- Plant Micronutrient Interactions and Effects
University of Michigan
1999-2025
China Agricultural University
2017-2025
Changzhi Medical College
2024-2025
Sun Yat-sen University
2012-2024
Fifth Affiliated Hospital of Sun Yat-sen University
2024
China Medical University
2024
First Hospital of China Medical University
2024
Nanning Normal University
2020-2024
Heilongjiang University of Chinese Medicine
2012-2024
Institute of Grassland Research
2022-2024
A novel label-free immunosensor for the detection of C-reactive protein (CRP) was developed based on a three-dimensional ordered macroporous (3DOM) gold film modified electrode by using electrochemical impedance spectroscopy (EIS) technique. The electrochemically fabricated with an inverted opal template, making surface area 3DOM up to 14.4 times higher than that classical bare flat one, characterized cyclic voltammetric (CV) which composed interconnected nanoparticles not only has good...
Metabolomics is a powerful new technology that allows the assessment of global low-molecular-weight metabolites in biological system and which shows great potential biomarker discovery. Analysis key body fluids has become an important part improving diagnosis, prognosis, therapy diseases. Hepatitis C virus (HCV) major leading cause liver disease worldwide serious burden on public health. However, lack small-animal model hampered analysis HCV pathogenesis. We hypothesize animal (Tupaia...
We present the first chromosome-level genome assembly of grasshopper, Locusta migratoria , one largest insect genomes. use coverage differences between females (XX) and males (X0) to identify X Chromosome gene content, find that shows both complete dosage compensation in somatic tissues an underrepresentation testis-expressed genes. X-linked content from L. is highly conserved across seven orders, namely Orthoptera, Odonata, Phasmatodea, Hemiptera, Neuroptera, Coleoptera, Diptera, 800 Mb...
Summary Adult stem cells are important in replenishing aged to maintain tissue homeostasis. Aging turn may exert profound effects on cell's regenerative potential, but date the mechanisms of such cell aging poorly understood, and it is not clear what extent contributes or organ aging. Here we show female Drosophila that germline (GSC) division rate progressively declines with age, which accompanied by reduced decapentaplegic ( dpp ) niche signaling pathway activation within GSCs. Egg...
Acinetobacter baumannii is an important opportunistic pathogen and multidrug-resistant isolate. Although tigecycline a potent antibiotic for treating infections with isolates, resistance becoming problem. This study aimed to explore the mechanism of in A. baumannii.A serial passage experiment was performed collect isolates selected by tigecycline. The expression efflux pumps quantified final isolate, 19606-T8. whole genome 19606-T8 sequenced putative mutations were confirmed using PCR Sanger...
A surprising electrochemiluminescence (ECL) enhancement effect in graded-gap CdSeTe@ZnS-SiO2 quantum dot (QD) bilayers was observed and used to create an ultrasensitive immunoassay. QDs of two different sizes were as a donor-acceptor pair, owing their tunable energy low biotoxicity. The QD fabricated by layer-by-layer assembly differently sized on glutaraldehyde-activated electrode. Benefiting from short interlayer distance perfect spectral overlap the bilayers, highly efficient ECL...
Following chicken domestication, diversified breeds were developed by both natural and artificial selection, which led to the accumulation of abundant genetic phenotypic variations, making chickens an ideal research model. To better understand structure under different selection pressures, we genotyped various populations with specific targets, including indigenous, commercial, gamecock, wild ancestral chickens, using 600K SNP array. We analyzed population structure, relationships, run...
Abstract A 3D ordered macroporous (3DOM) ionic‐liquid‐doped polyaniline (IL‐PANI) inverse opaline film is fabricated with an electropolymerization method and gold nanoparticles (AuNPs) are assembled on the by electrostatic adsorption, which offers a promising basis for biomolecular immobilization due to its satisfactory chemical stability, good electronic conductivity, excellent biocompatibility. The AuNP/IL‐PANI could be used fabricate electrochemical impedance spectroscopy (EIS)...
Acylglycerol kinase (AGK) is reported to be overexpressed in multiple cancers. The clinical significance and biological role of AGK breast cancer, however, remain established. expression cancer cell lines, paired patient tissues were determined using immunoblotting Real-time PCR. 203 human tissue samples analyzed by immunochemistry (IHC) investigate the relationship between clinicopathological features cancer. Functional assays, such as colony formation, anchorage-independent growth BrdU...
Triple‐negative breast cancer (TNBC) is the most aggressive subtype of with high proliferative and metastatic phenotypes. CDCA7, a new member cell division cycle associated family genes, involved in embryonic development dysregulated various types human cancer. However, biological role molecular mechanism CDCA7 TNBC have not been defined. Herein, we found that was preferentially markedly expressed lines tissues. High expression relapse status predicted poorer disease‐free survival patients...
Geese are among the most important poultry species in world. The current generally accepted hypothesis is that European domestic geese originated from greylag (Anser anser), and Chinese have two origins, of which swan cygnoides), Yili goose geese. To explain origin demographic history geese, we selected 14 breeds Europe China wild populations whole genome sequencing data were obtained for 74 samples.Population structure analysis phylogenetic trees showed ancestor except Yili, Analysis...
A large number of immune receptors consist nucleotide binding site-leucine rich repeat (NBS-LRR) proteins and leucine repeat-receptor-like kinases (LRR-RLK) that play a crucial role in plant disease resistance. Although many NBS-LRR genes have been previously identified Zea mays, there are no reports on identifying encoded the N-terminal Toll/interleukin-1 receptor (TIR) motif genome-wide LRR-RLK genes. In present study, 151 226 were after performing bioinformatics analysis entire maize...
Abstract Background Since the domestication of chicken, various breeds have been developed for food production, entertainment, and so on. Compared to indigenous chicken which generally do not show elite production performance, commercial or lines are selected intensely meat egg production. In present study, in order understand molecular mechanisms underlying dramatic differences number between egg-type chickens chickens, we performed a genome-wide association study (GWAS) mixed linear model....
The quality of poultry eggshells is closely related to the profitability egg production. Eggshell speckles reflect an important trait that influences appearance and customer preference. However, mechanism speckle formation remains poorly understood. In this study, we systematically compared serum immune antioxidant indices hens laying speckled normal eggs. Transcriptome methylome analyses were used elucidate eggshell formation.The results showed seven differentially expressed genes (DEGs)...
We utilized the proteomic approach to investigate proteome of fifth instar hemolymph during growth and development, improve understanding this important bioprocess gene expression situation. A total 25 μL was used for 2D analysis, separated proteins were visualized by silver staining analyzed using ImageMaster software. The report showed as many 241 protein spots expressed in beginning instar. Among them, most concentrated pI 3.5−6.5, which reached 76% spots. As molecular sizes, 182 between...
Stem cells are critical for maintaining tissue homeostasis and commonly governed by their niche microenvironment, although the intrinsic mechanisms controlling multipotency poorly understood. Polycomb group (PcG) genes epigenetic silencers, have emerged recently as important players in stem cell preventing initiation of differentiation programs. Here we describe an unexpected role specific PcG allowing adult cell-derived tumor development. We show that Posterior sex combs ( Psc ), which...