- Sarcoma Diagnosis and Treatment
- Testicular diseases and treatments
- Ovarian cancer diagnosis and treatment
- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Cardiac tumors and thrombi
- Preterm Birth and Chorioamnionitis
- Pregnancy and preeclampsia studies
- Radiomics and Machine Learning in Medical Imaging
- Vascular Tumors and Angiosarcomas
- Colorectal and Anal Carcinomas
- Infant Development and Preterm Care
- Soft tissue tumor case studies
- Tumors and Oncological Cases
- Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Maternal and Perinatal Health Interventions
- Respiratory viral infections research
- Maternal and fetal healthcare
- Pregnancy-related medical research
- Management of metastatic bone disease
- Retinopathy of Prematurity Studies
- Bone Tumor Diagnosis and Treatments
- Neuroscience of respiration and sleep
Institut Bergonié
2015-2024
Centre Hospitalier Universitaire de Saint-Étienne
2015-2024
Université Jean Monnet
2017-2024
Inserm
2017-2024
Biologie, ingénierie et imagerie pour l'Ophtalmologie
2022-2024
Hôpital Nord
2024
SAnté INgenierie BIOlogie Saint-Etienne
2021-2023
University College Cork
2022-2023
Infant
2022
McGill University
2017-2020
NETSARC (netsarc.org) is a network of 26 sarcoma reference centers with specialized multidisciplinary tumor boards (MDTB) aiming to improve the outcome patients. Since 2010, presentation an MDTB and expert pathological review are mandatory for patients nationwide. In present work, impact surgery in center on survival investigated using this national registry.
Well-designed observational studies of individuals with rare tumors are needed to improve patient care, clinical investigations, and the education healthcare professionals.The patterns outcomes, prognostic factors a cohort 2225 patients metastatic soft tissue sarcomas who were diagnosed between 1990 2013 documented in prospectively maintained database French Sarcoma Group analyzed.The median number systemic treatments was 3 (range, 1-6); 27% did not receive any treatment 1054 (49%) underwent...
BACKGROUND The objective of this study was to describe characteristics at diagnosis and outcomes adults with soft tissue sarcoma. METHODS authors conducted a retrospective multicenter 12,262 patients who were treated between January 1980 31 December 2013 in French Sarcoma Group centers enrolled the “Conticabase.” Diagnoses systematically reviewed by expert pathologists, entities classified according World Health Organization classification. Diagnostic characteristics, treatments, are...
Abstract Group B Streptococcus (GBS) is one of the most common bacteria isolated in human chorioamnionitis, which a major risk factor for premature birth and brain injuries. Males are at greater than females developing lifelong neurobehavioural disorders, although origins this sex bias remain poorly understood. We previously showed that end-gestational inflammation triggered by GBS led to early neurodevelopmental impairments mainly male rat progeny. Identifying key inflammatory players...
While heart rate variability (HRV) constitutes a relevant non-invasive tool to assess the autonomic nervous system (ANS) function with recognized diagnostic or therapeutic implications, there is still lack of established data on maturation control during first months life. The Autonomic Baby Evaluation (AuBE) cohort was built establish, normal profile from birth up 2 years, in healthy population full-term newborns.Heart analysis carried out 271 newborns (mean gestational age 39 wGA + 5 days)...
Risk assessment of gastrointestinal stromal tumor (GIST) according to the AFIP/Miettinen classification and mutational profiling are major tools for patient management. However, depends heavily on mitotic counts, which is laborious sometimes inconsistent between pathologists. It has also been shown be imperfect in stratifying patients. Molecular testing costly time-consuming, therefore, not systematically performed all countries. New methods improve risk molecular predictions hence crucial...
Abstract Aim To test the association between perinatal inflammation exposure and Full‐Scale IQ (FSIQ) score 7 years after neonatal arterial ischaemic stroke (NAIS). Method We conducted a cross‐sectional ancillary study nested in multicentric longitudinal French cohort of infants born at term with NAIS November 2003 October 2006. Seventy‐three children were included (45 males, 28 females). The priori defined primary outcome measure was FSIQ assessed Wechsler Intelligence Scale for Children,...
ObjectiveTo test the association between exposure to perinatal inflammation – i.e. clinical chorioamnionitis or early-onset neonatal infection in preterm children without severe brain injury and neurodevelopmental outcome at 30 months of corrected age (CA).DesignCross-sectional study from a French regional cohort follow-up (SEVE Network).PatientsOne hundred sixty-four surviving neonates namely, grade III IV cerebral hemorrhage cystic periventricular leukomalacia late-onset necrotizing...
(1) Background: The Ages and Stages Questionnaire-Third Edition (ASQ-3) is a parental screening questionnaire increasingly being used to evaluate the development of preterm children. We aimed assess classification performance ASQ-3 in infant follow-up. (2) Methods: In this cross-sectional study, we included 185 children from SEVE longitudinal cohort born <33 weeks gestational age between November 2011 January 2018, who had both an score at 24 months corrected (CA) revised Brunet-Lézine (RBL)...
Abstract Infant pose estimation is crucial in different clinical applications, including preterm automatic general movements assessment. Recent infant methods are limited by a lack of real data and mainly focused on 2D detection. We introduce stereoscopic system for infants’ 3D estimation, based fine-tuning state-of-the-art human networks large, real, manually annotated dataset images. Our contains over 88k images, collected from 175 videos 53 premature infants born <33 weeks gestational...
Background: Missing covariates are common in observational research and can lead to bias loss of statistical power. Limited data regarding prognostic factors survival outcomes sarcomas irradiated fields (SIF) available. Because the long lag time between irradiation first cancer scarcity SIF, missing a critical issue when analyzing long-term outcomes. We assessed overall (OS), progression-free (PFS), metastatic-progression-free (MPFS) survivals SIF using three methods account for covariates....
The General Movement Assessment (GMA) is a validated evaluation of brain maturation essential to shaping early individual developmental trajectories preterm infants. To ensure reliable GMA, infants should be recorded for 30 60 min before manually selecting at least three sequences with general movements. This time-consuming task short video from lengthy recordings impedes its implementation within the Neonatal Unit. Moreover, an accurate pose estimation tool paramount developing field GMA...
11014 Background: There are only limited data on the outcome of pts with metastatic STS according to histological subtype and treatment setting. Methods: Data from 2225 included in CONTICANET database were analyzed. Histological diagnosis was centrally reviewed all cases. Time next (TNT) defined time systemic onset or death any cause, whichever comes first. Overall survival (OS) last patient contact cause. Results: Median follow-up 58 months. age 56 yrs (range 18-93). The five most frequent...