- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Optical Coherence Tomography Applications
- Ultrasonics and Acoustic Wave Propagation
- Electrical and Bioimpedance Tomography
- Ultrasound and Hyperthermia Applications
- Soft Robotics and Applications
- Surgical Simulation and Training
- Venous Thromboembolism Diagnosis and Management
- Coronary Interventions and Diagnostics
- Advanced X-ray and CT Imaging
- Ultrasound and Cavitation Phenomena
- Augmented Reality Applications
- Experimental and Theoretical Physics Studies
- Integrated Circuits and Semiconductor Failure Analysis
- Optical Systems and Laser Technology
- Engineering Applied Research
- Optical Polarization and Ellipsometry
- Orbital Angular Momentum in Optics
- Diabetes Management and Research
- Advanced MRI Techniques and Applications
- Wireless Power Transfer Systems
- Piezoelectric Actuators and Control
- Random lasers and scattering media
- Microwave Imaging and Scattering Analysis
Johnson & Johnson (Italy)
2020-2021
Erasmus MC
2016-2018
Erasmus University Rotterdam
2017-2018
Delft University of Technology
2018
Rotterdam University of Applied Sciences
2016
This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, has circular active area with diameter 1.5 mm on top which 2-D array piezoelectric transducer elements integrated. It requires only four micro-coaxial cables interface 64 receive (RX) 16 transmit (TX) imaging system. To do so, it routes high-voltage (HV) pulses generated by...
Intravascular ultrasound (IVUS) is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking IVUS (FL-IVUS), instead conventional side-looking geometry. Volumetric can be achieved with 2-D array transducers, which present major challenges in reducing cable count and device integration. In this work, we 80-element lead zirconium titanate matrix transducer for FL-IVUS a front-end...
We present a form of acoustic microscopy, called Structured Ultrasound Microscopy (SUM). It creates volumetric image by recording reflected echoes ultrasound waves with structured phase front using moving single-element transducer and computational reconstruction. A priori knowledge the field produced single element allows us to relate received 3D scatter map within beam itself, leading an isotropic resolution at all depths. An aberration mask in imposes structure, broadening breaking...
Objective: Minimally invasive procedures, such as intravascular and intracardiac interventions, may benefit from guidance with forward-looking (FL) ultrasound. In this work, we investigate FL ultrasound imaging using a single-element transducer integrated in steerable catheter, together an optical shape sensing (OSS) system. Methods: We tested the feasibility of proposed device by surface tissue-mimicking (TM) phantom ex vivo human carotid plaque. While manually steering catheter tip,...
This article presents an application-specific integrated circuit (ASIC) designed for intra-vascular ultrasound imaging that interfaces 64 piezoelectric transducer elements to system using a single micro-coaxial cable. Thus, it allows single-element be replaced by array enable 3-D imaging. The 1.5-mm-diameter ASIC is intended mounted at the tip of catheter, directly with 2-D elements. For each these elements, contains high-voltage (HV) switch, allowing transmit acoustic wave in response HV...
In the field of vascular interventions, forward-looking intravascular ultrasound transducers (FL-IVUS) are needed for better visualization complex lesions, such as chronic total occlusions. this work, we propose a strategy 3D imaging using single-element transducer and an optical shape sensing fiber (OSS) in steerable catheter tip. We evaluate performance integrated device by six-wire phantom submerged water. While steering tip across wires, OSS data acquired continuously. combine distance...
This paper presents a front-end ASIC for forward-looking intravascular ultrasound (IVUS) imaging. The is intended to be mounted at the tip of catheter and can interface total 80 piezo-electric transducer elements with an imaging systems using only 4 cables, thus significantly reducing system complexity compared prior art. It capable switching high-voltage transmit pulses 16 elements, capturing resulting echo signals 64 multiplexed receive elements. digitizes received locally, providing more...
In medical ultrasound transducer design, the geometry of individual elements is crucial since it affects vibration mode each element and its radiation impedance. For a fixed frequency, optimal (i.e., uniform surface motion) can be achieved by designing with very small width-to-thickness ratios. However, for impedance highest radiated power), width should as large possible. This leads to contradiction that solved subdicing wide elements. To systematically examine effect on performance 1-D...
Even though technological advances have increased the application area of minimally invasive surgery (MIS), there are still hurdles to allow for widespread adoption more complex procedures. The development steerable instruments, in which surgeon can alter tip orientation, has MIS, but they bulky, limits their ability navigate through narrow environments, and complex, complicates miniaturization. Furthermore, do not navigating anatomies. In an effort improve dexterity MIS while minimizing...
This paper presents an ASIC (Application Specific Integrated Circuit) design for a catheter probe that interfaces 64 piezoelectric elements directly integrated on top of the to imaging system using single micro-coaxial cable. Each piezo can be used both transmit (TX) and receive (RX), enabling full synthetic aperture imaging. A prototype has been realized with 1.5 mm diameter circular layout, intended 3D intra-vascular ultrasound The functionality this successfully demonstrated in...
In interventional cardiology catheters are routinely used to access and treat defects diseases in the heart. Image guidance using forward-looking (FL)ultrasound transducers at tip of catheter could give physician visual feedback during complex procedures such as valve replacement or transseptal puncture. this work, we investigate FL 3D imaging by integrating a 7 MHz single-element ultrasound transducer novel multi-steerable intracardiac together with an optical shape sensing fiber (OSS). We...
In ultrasound imaging, one of the challenges transducer design is to maximize acoustic energy that radiated into medium. The geometry elements major aspects affects transmit efficiency. this study we apply simulations investigate effect subdicing on performance an linear array transducer. We focus influence average emitted pressure, surface velocity and radiation impedance arrays with variable element widths. are performed using Finite Element Analysis (FEA) software PZFlex (Weidlinger...
Accurate diagnostics of stenosis and blood flow distribution in carotid arteries requires transducers capable producing 3D volume images with high frame rate for real time imaging. In the process designing a matrix probe, an important goal is to realize acoustic stack sensitivity bandwidth. this study, we employ finite element analysis evaluate effect sub-dicing on performance piezoelectric array. The array integrated Application Specific Integrated Circuit (ASIC), which performs task signal...
Abstract Background Vascular thrombosis can be treated pharmacologically, however, serious shortcomings such as bleeding may occur. Several studies suggest that sonothrombolysis induce lysis of the clots using ultrasound. Moreover, intravenously injected thin-shelled microbubbles (MBs) combined with ultrasound further improve clot lysis. Thick-shelled MBs have been used for drug delivery, targeting and multimodal imaging. However, their capability to enhance is unknown. In this study, an...
Complex intravascular lesions, such as chronic total occlusions (CTOs), require forward-looking imaging. We propose to use a 25 MHz single-element transducer and an optical shape sensing (OSS) fiber integrated into steerable catheter achieve imaging in approach. A tissue-mimicking phantom with three hollow channels (3, 2 1 mm diameter) two steel spheres (1.5 is used target. Ultrasound data OSS are simultaneously acquired while steering rotating 8.5 F bidirectional tip flexion. The obtained...
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