A5009043754- Nanoplatforms for cancer theranostics
- Tissue Engineering and Regenerative Medicine
- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
Imperial College London
2023
3D organoids are widely used as tractable in vitro models capable of elucidating aspects human development and disease. However, the manual low-throughput culture methods, coupled with a low reproducibility geometric heterogeneity, restrict scope application organoid research. Combining expertise from stem cell biology bioengineering offers promising approach to address some these limitations. Here, melt electrospinning writing is generate tuneable grid scaffolds that can guide...
Semiconducting polymer nanoparticles (SPNs) are explored for applications in cancer theranostics because of their high absorption coefficients, photostability, and biocompatibility. However, SPNs susceptible to aggregation protein fouling physiological conditions, which can be detrimental vivo applications. Here, a method achieving colloidally stable low-fouling is described by grafting poly(ethylene glycol) (PEG) onto the backbone fluorescent semiconducting polymer,...