A5007413489- Toxic Organic Pollutants Impact
- Air Quality and Health Impacts
- Atmospheric chemistry and aerosols
- Carcinogens and Genotoxicity Assessment
- Vehicle emissions and performance
- Free Radicals and Antioxidants
- Bioactive Compounds and Antitumor Agents
- Indoor Air Quality and Microbial Exposure
- Effects and risks of endocrine disrupting chemicals
- Genomics, phytochemicals, and oxidative stress
- Estrogen and related hormone effects
- Synthesis and Biological Evaluation
- Analytical Chemistry and Chromatography
- Atmospheric Ozone and Climate
- Air Quality Monitoring and Forecasting
- Odor and Emission Control Technologies
- Phytoestrogen effects and research
- Data Management and Algorithms
- Climate Change and Health Impacts
- Oil Spill Detection and Mitigation
- Per- and polyfluoroalkyl substances research
- Analytical chemistry methods development
- Environmental Toxicology and Ecotoxicology
- Water Treatment and Disinfection
- Inhalation and Respiratory Drug Delivery
Kyoto University
2014-2025
Kanazawa University
2006-2016
Osaka Prefecture University
2004-2007
University of Washington
2007
Estrogenic/antiestrogenic activities of 14 polycyclic aromatic hydrocarbons (PAHs) and 63 monohydroxylated PAHs (OHPAHs) having 2 to 6 rings were evaluated by yeast two-hybrid assay expressing human estrogen receptor α. Relative effective potencies estrogenic antiestrogenic calculated as the inverse values relative concentration test compound that gave same E2 4-hydroxytamoxifen, respectively. did not show any estrogenic/antiestrogenic activity, but several OHPAHs 3 5 showed activities....
Polycyclic aromatic compounds are ubiquitous atmospheric pollutants with toxic, mutagenic, and carcinogenic properties. They produced from chemical reactions of their parent in the atmosphere as well a wide variety anthropogenic sources such fuel combustions. The present review is mainly concerned several reaction pathways regarding secondary formation polycyclic hydrocarbon (PAH) derivatives, i.e., mutagenic nitrated PAHs, 1- 2-nitrotriphenylene, via gas-phase OH or NO3 radical-initiated...
Chiang Mai and several other provinces in northern Thailand have been annually facing air pollution problems during the dry season. Ten polycyclic aromatic hydrocarbons (PAHs); 19 nitropolycyclic (NPAHs); levoglucosan (LG), a marker for biomass burning, were quantified total suspended particulates (TSP) collected dry, transition, wet seasons 2010. The concentrations of PAHs NPAHs season significantly higher than [Benzo[a]pyrene (BaP)] – [benzo[ghi]perylene (BghiPe)] ratio, as an indicator...
Abstract Atmospheric nitrated polycyclic aromatic hydrocarbons (NPAHs), which have been shown to adverse health effects such as carcinogenicity, are formed in part through nitration reactions of their parent (PAHs) the atmosphere. However, little is known about heterogeneous rates PAHs by gaseous NO 2 on natural mineral substrates, desert dust aerosols. Herein employing kinetic experiments using a flow reactor and surface analysis Fourier transform infrared spectroscopy with pyridine...
1-Nitropyrene (1-NP) is one of the most abundant nitrated polycyclic aromatic hydrocarbons (NPAHs) in diesel exhaust particulate matter (DEP) and a main contributor direct-acting mutagenicity DEP. Therefore, metabolites 1-NP are expected to be biomarker for assessment exposure In this study, highly specific sensitive analytical method using liquid chromatography with tandem mass spectrometry (LC-MS/MS) was developed determine urinary metabolites. After enzymatic hydrolysis conjugated...
The effect of four ortho-quinoid polycyclic aromatic hydrocarbons (PAHs) and seven para-quinoid PAHs on the viability A549 cells were examined. [1,2-naphthoquinone (1,2-NQ), 9,10-phenanthrenquinone (9,10-PQ), 5,6-chrysenequinone (5,6-CQ), benzo[c]phenanthrene-5,6-quinone (B[c]P-5,6-Q)] overproduced hydrogen peroxide (H2O2) without being consumed themselves. These had strong cytotoxic effects except for 1,2-NQ, since its tendency to covalently bind thiol groups. cytotoxicity appears be due...
We developed a sampler for collecting atmospheric polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic (NPAHs) by attaching glass column packed with XAD-4 resin to the gas sampling port of high-volume air equipped filter. When upper bottom layers were 64 g 32 resin, respectively, all PAHs NPAHs in phase quantitatively collected without any break through, while particle on samples at suburban downtown Kanazawa using proposed sampler. It was found that about 95% 2-3 ring more than 99%...
Benzo[a]pyrene is an important indicator of polycyclic aromatic hydrocarbons pollution that exhibits complex atmospheric dynamics influenced by meteorological factors and suspended particulate matter (SPM). Herein, the influencing B(a)P concentration were elucidated analyzing monthly environmental data for Kyoto, Japan, from 2001 to 2021 using improved association rule algorithm. Results revealed concentrations 1.3–3 times higher in cold seasons than warm SPM lower seasons. The clustering...
Combustion-derived magnetite has recently attracted attention for its health risks and potential impact on atmospheric heating/cooling. This study provides new observational insights into the relationship between black carbon (BC) at a remote site in East Asia, Japan, focusing combustion sources, seasonal trends, overestimation of BC by light-absorbing magnetite. Magnetic measurements PM2.5 samples, complemented detailed chemical analyses, reveal similar temporal variations while...
Diesel exhaust particles (DEPs) contain oxygen-containing polycyclic aromatic hydrocarbons (PAHs) called quinoid PAHs. Some PAHs generate free radicals as they undergo enzymatic and nonenzymatic redox cycling with their corresponding semiquinone radicals. Reactive oxygen species (ROS) produced by these reactions can cause severe oxidative stress connected inflammatory processing. Although humans animals are continuously exposed to chemicals in the environment, little is known about which...
Airborne particulates were collected in nine size fractions by using Andersen low-volume air samplers the cities of Shenyang, Fushun, and Tieling, Liaoning Province, northeast China, during period from July 2001 through December 2003. Nine polycyclic aromatic hydrocarbons (PAHs) seven nitropolycyclic (NPAHs) airborne determined. The mean concentrations sums PAHs NPAHs highest which is an industrial city, lowest a commercial although consumption petroleum coal largest Shenyang. grouped into...