A5071063280- Cardiac electrophysiology and arrhythmias
- Ion channel regulation and function
- Cardiac tumors and thrombi
- Diet and metabolism studies
- Computational Drug Discovery Methods
- Postharvest Quality and Shelf Life Management
- Trypanosoma species research and implications
- Polysaccharides Composition and Applications
- Streptococcal Infections and Treatments
- Anesthesia and Sedative Agents
- Infections and bacterial resistance
- Oral Health Pathology and Treatment
- Management of metastatic bone disease
- Anesthesia and Neurotoxicity Research
- Cardiovascular Effects of Exercise
- Nutrition, Health and Food Behavior
- Sarcoma Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
- Neurological Disorders and Treatments
- Cardiovascular and exercise physiology
- Medical Imaging and Analysis
- Research on Leishmaniasis Studies
- Ion Channels and Receptors
- Fungal Infections and Studies
- Vascular Tumors and Angiosarcomas
University of Szeged
2021-2024
Iraqi University
2022
University of Alkafeel
2022
Altoosi University College
2022
University of Aden
2022
Shandong University
2020
Nizam's Institute of Medical Sciences
2019
BACKGROUND: Atrial fibrillation (AF) susceptibility is heightened in endurance athletes but the underlying mechanisms are incompletely understood. Because pulmonary vein (PV) myocyte triggers critical determinants of AF, we investigated PV electrophysiological remodelling animal models athlete's heart. METHODS: The following experiments were performed canines and mice after 16 or 6 weeks, respectively, daily exercise training (ExT), compared to sedentary (Sed) controls: ECG recording,...
Abstract Recent experimental data shows that hesperetin, a citrus flavonoid, affects potassium channels and can prolong the QT c interval in humans. Therefore, present study we investigated effects of hesperetin on various transmembrane ionic currents ventricular action potentials. Transmembrane current measurements potential recordings were performed by patch-clamp conventional microelectrode techniques dog rabbit preparations. At 10 µM concentration did not, however, at 30 significantly...
Even though rodents are accessible model animals, their electrophysiological properties deeply different from those of humans, making the translation rat studies to humans rather difficult. We compared mechanisms ventricular repolarization in various animal models by measuring cardiac action potentials papillary muscle preparations using conventional microelectrodes and applying selective inhibitors potassium transmembrane ion currents. Inhibition IK1 current (10 µmol/L barium chloride)...
Skin and soft tissue infections are frequent. Candidiasis Aspergillosis the most common cutaneous fungal infections. Yemeni alum (Aluminium Potassium Sulphate) is a natural mineral with antifungal antibacterial properties. This study aimed to confirm alum's effectiveness against selected strains develop useful topical formulations. Using different concentrations, we prepared twenty-three formulations, including four non-adjusted aqueous solutions, eight adjusted pH glycerite three Oil/Water...
The present study was designed to test the hypothesis that selectivity of blocking late Na+ current (INaL) over peak (INaP) is related fast offset kinetics channel inhibitor. Therefore, effects 1 µM GS967 (INaL inhibitor), 20 mexiletine (I/B antiarrhythmic) and 10 quinidine (I/A on INaL INaP were compared in canine ventricular myocardium. estimated as maximum velocity action potential upstroke (V+max). Equal amounts dissected by applied drug concentrations under APVC conditions. inhibition...
Abstract The antiarrhythmic and cardiac electrophysiological effects of SZV-2649 that contains a 2,6-diiodophenoxy moiety but lacks the benzofuran ring system present in amiodarone, were studied mammalian cell line, rat dog preparations. exerted against coronary artery occlusion/reperfusion induced ventricular arrhythmias rats acetylcholine- burst stimulation atrial fibrillation dogs. inhibited hERG GIRK currents HEK cells (IC 50 : 342 529 nM, respectively). In canine myocytes, (10 µM)...
Myxosarcomas are rare malignant tumors of soft connective tissues, classified into various subtypes, including myxoid liposarcoma, chondrosarcoma, and leiomyosarcoma. In this study, we proposed to study the demographic, tumor characteristics, overall survival rate compared treatment modalities between these cancers. Patient data collected based on locoregional metastasis presentation abovementioned with a cutoff duration up 10 years were obtained from SEER database during 1975‐2016. Our...
Forced degradation is a process that involves of drug products and substances at conditions more severe than accelerated thus generates can be studied to determine the stability molecules. Five different brands Ceftriaxone injection were collected from market exposed various stress condition like alkaline, acidic, oxidative thermal degradation. The was followed by using spectrophotometric analysis. All antibiotic undergo forced in ranges maximum observed basic medium.
Introduction: Tokuhashi's scoring has been used as a presurgical tool for prediction of survival in patients with spinal metastases (SM). It evaluates prognostic factors such performance status, number extraspinal bone metastasis, metastasis to visceral organs, site primary, and neurological status that determine the these patients. To best our knowledge, only limited studies are available use this system outcomes SMs undergoing palliative radiotherapy.Aim: The purpose study was patient...
Skin and soft tissue infections are common. Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa cause most bacterial skin infections. Yemen's alum is a natural mineral with potent antibacterial antifungal activity. The current study aimed to verify Yemen alum's activity against chosen strains formulate valuable topical preparation. We formulated twenty-three formulations involving four non-adjusted aqueous solutions, eight adjusted pH three Oil/Water cream...
Nourishment is essential for the continuity of life in all animals' kinds.Fasting one world's most widespread fitness and health fads enhancing their simplifying lives.The low-fat diet used applications to maintain levels different hormones therefore decreased risk diseases such as cardiovascular disease.Thus, current study was designed investigate effect a low-Fat Diet tow period strategy fasting 14 hours 20 by using 36 healthy young male albino rats on testosterone follicle stimulation hormone.
H Introduction: The brain is the target organ for both general anesthetic drugs and some that are used to treat nervous disorders which cause activation such as piracetam citicoline however, they work in contrast each other.Objective: Our study set out determine effect of on induction time.Method: For 10 days 24 mice had been treated with three groups (piracetam group, mix group).In addition, 7 were a control group.All assessed open field test underwent right reflex pain tests.Results:...
Rodents are commonly used as models in electrophysiology. However, distinct differences exist between large animals and rodents terms of their ion channel expression action potential shapes, possibly limiting the translational value findings obtained rodents. We aimed for a direct comparison possible impact selective inhibition channels on cardiac repolarization preparations from human hearts model species. applied standard microelectrode technique at 37°C ventricular (papillary muscles...