A5100615315- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Vascular Tumors and Angiosarcomas
- Blood groups and transfusion
- Virology and Viral Diseases
- Tumors and Oncological Cases
- Malaria Research and Control
- MicroRNA in disease regulation
- Vascular Malformations and Hemangiomas
- interferon and immune responses
- Circular RNAs in diseases
Chinese Academy of Medical Sciences & Peking Union Medical College
2005-2025
Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore effect ZIKV and its underlying mechanism. Methods: We performed RNA-Seq in A549 cells with or without infection. RIG-I was overexpressed by plasmid transfection knocked down siRNA cells. Expression levels mRNA protein selected genes were detected RT-qPCR Western...
ABSTRACT Utilize 16S rRNA sequencing technology to characterize bacterial species susceptible people living with HIV (PLWH) across different stages. This mapping aims establish a foundational framework for preventing secondary infections, prolonging patient survival, enhancing quality of life, and advancing the diagnosis, treatment, research co‐infections. In this study, we classified participants into three groups: The blood donors (DI group), AIDS patients who have received ART treatment...
The CT manifestation of lymphangiohemangioma in a 17-year-old boy is reported. A mass composed the central malformed, dilated venous channels and peripheral unenhanced soft tissue was revealed anterior mediastinum. feeding enhancement very characteristic. diagnosis made by pathologic study surgical specimen.
Aim: TMEM2 has been demonstrated to suppress HBV infection by activating the Jak/STAT pathway. In this study, we sought explore mechanism which effects on Zika virus (ZIKV) replication. Materials & methods: was overexpressed. Selected gene mRNA, p-STAT1 levels and interferon stimulated response element activity were examined qRT-PCR, Western blot luciferase assay respectively. Results: Overexpression of significantly inhibited ZIKV replication, upregulated MDA5 RIG-I expression, increased...
Although Zika virus (ZIKV) infection is mainly transmitted through mosquito bite, it can also be blood transfusion. More than 500 000 cases of ZIKV were reported in the Americas from 2015 to 2016. Up till now, over 10 imported have been due frequent international exchanges Shenzhen city Guangdong Province, China. Unfortunately, there no data on Chinese donors because has not included routine screening for volunteer donors. As such, we performed a preliminary survey prevalence among Shenzhen,...