Jia Wei Chen

ORCID: 0000-0003-2219-0936
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Atherosclerosis and Cardiovascular Diseases
  • Diabetes Treatment and Management
  • Heart Failure Treatment and Management
  • Adipokines, Inflammation, and Metabolic Diseases
  • Coronary Interventions and Diagnostics
  • Liver Disease Diagnosis and Treatment
  • Inflammation biomarkers and pathways
  • Angiogenesis and VEGF in Cancer
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Gastric Cancer Management and Outcomes
  • Cardiac Imaging and Diagnostics
  • Cell Adhesion Molecules Research
  • Gout, Hyperuricemia, Uric Acid
  • Extracellular vesicles in disease
  • Cardiac electrophysiology and arrhythmias
  • Coenzyme Q10 studies and effects
  • Acute Myocardial Infarction Research
  • Pelvic floor disorders treatments
  • Esophageal Cancer Research and Treatment
  • Metastasis and carcinoma case studies
  • Kawasaki Disease and Coronary Complications
  • Urinary Bladder and Prostate Research
  • Cardiovascular Disease and Adiposity

Fujian Medical University
2024

Lianyungang Oriental Hospital
2024

Xiamen University
2024

Guangzhou Medical University
2024

Guangzhou First People's Hospital
2024

South China University of Technology
2024

Shanghai Jiao Tong University
2017-2023

Ruijin Hospital
2017-2022

Shanxi Medical University
2021

Beijing Friendship Hospital
2012

Background: Chronic inflammatory disorders and dyslipidemia in type 2 diabetes mellitus (T2DM) are essential contributors to the development of atherosclerotic cardiovascular disease. Monocyte high-density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel simple measure associated positively with body oxidative stress status. However, little known regarding role MHR evaluating carotid intima-media thickness (CIMT), surrogate predictor subsequent vascular events, especially diabetic...

10.3389/fendo.2019.00191 article EN cc-by Frontiers in Endocrinology 2019-04-04

Abstract Background The prevalence of stress urinary incontinence (SUI) in adult female Taiyuan and what are the related risk factors not clear. aim this study was to provide a basis for exploring prevention treatment SUI Taiyuan. Methods A voluntary online questionnaire used investigate community surrounding townships Most questionnaires refer International Consultation on Incontinence Questionnaire-Female Lower Urinary Tract Symptoms, adapt specific circumstances region. Data were analyzed...

10.1186/s12905-021-01319-z article EN cc-by BMC Women s Health 2021-04-22

Background Because of advances in medical treatments, a substantial proportion patients with heart failure (HF) have experienced recovery ejection fraction (EF), termed HF recovered EF (HFrecEF). Insulin resistance (IR) is prevalent and tightly related prognosis. This study investigates the relationship between IR incidence HFrecEF who are nondiabetic. Methods Results A total 262 reduced (HFrEF) were nondiabetic consecutively enrolled. Patients classified into (follow-up EF>40% ≥10% absolute...

10.1161/jaha.122.026184 article EN cc-by-nc-nd Journal of the American Heart Association 2022-09-21

Microalbuminuria (MA) is considered a major risk factor predisposing to cardiovascular morbidity and mortality. Outcomes after percutaneous coronary intervention (PCI) for patients with acute myocardial infarction (AMI) complicated by MA have been well described. However, data regarding admission flow are scant. The aims of this study were evaluate the effects on blood prognosis in ST-segment elevation (STEMI) undergoing primary PCI.Did elevated microalbuminuria predict poor 6-month...

10.1002/clc.21005 article EN Clinical Cardiology 2012-01-19

Abstract High-density lipoprotein (HDL) confers protection against cardiovascular disease partly attributable to its robust anti-oxidant activities, which is largely impaired in diabetic conditions. In this study, we analyzed the activity of HDL, as represented by arylesterase paraoxonase 1 (PON1) HDL particles, 216 consecutive HF patients with (n = 79) or without 137) type 2 diabetes, and age- gender-matched 112 189 non-diabetic non-HF controls. We found was significantly decreased than HF,...

10.1038/s41598-019-42518-x article EN cc-by Scientific Reports 2019-04-12

Background A substantial portion of heart failure (HF) patients adherent to guideline-directed medical therapies have experienced improved ejection fraction (EF), termed HFimpEF. Glycemic variability (GV) has emerged as a critical cardiometabolic factor. However, the relation between long-term GV and incidence HFimpEF is still unclear. Methods total 591 hospitalized HF with reduced EF (HFrEF, EF≤ 40%) admitted from January 2013 December 2020 were consecutively enrolled. Repeat...

10.3389/fendo.2023.1211954 article EN cc-by Frontiers in Endocrinology 2023-09-20

Left ventricular (LV) diastolic dysfunction (LVDD) is the defining feature of heart failure with preserved ejection fraction (HFpEF) and predicts subsequent incident (HF) all-cause mortality. Mounting evidence reveals that cardiometabolic risk factors play critical roles in development LVDD. In this study, we sought to investigate relation between serum uric acid (SUA) level progression LVDD apparently healthy patients. A total 1082 subjects without diagnosed cardiovascular disease were...

10.1155/2022/9927254 article EN cc-by Disease Markers 2022-10-15

Aberrant changes in endothelial phenotype and morphology are considered to be initial events the pathogenesis of atherosclerosis. Direct observation intact endothelium will provide valuable information for understanding cellular molecular dysfunctional cells. Here, we describe a modified en face immunofluorescence staining technique which enables scientists obtain clear images surface analyze molecule expression patterns situ. The method is simple reliable observing entire monolayer at...

10.3791/59325 article EN Journal of Visualized Experiments 2019-08-20

The data presented in this article are related to the research entitled "Increased serum TREM-1 level is associated with in-stent restenosis, and activation of promotes inflammation, proliferation migration vascular smooth muscle cells" (Wang et al., 2017) [1], which demonstrated that expressed on cells (VSMCs) cultured VSMCs. In dataset, expression leukocytes endothelial carotid artery after ligation was evaluated. effect stenosis analyzed human saphenous veins (HSVs) spontaneously undergo...

10.1016/j.dib.2017.11.065 article EN cc-by Data in Brief 2017-11-23

Objective To compare the detection rate and diagnostic accuracy of cardia polyps using endoscopy with blue laser imaging (BLI) white‐light (WLI). Methods Patients were randomly divided into BLI group WLI according to endoscopic procedures. followed by was conducted in group, whereas examination group. The number, size, microstructure, microvascular patterns detected recorded. Biopsy then performed. Results higher than that (7.87% vs 4.22%, P = 0.018). overlooked lesions lower (0.64% 3.38%,...

10.1111/1751-2980.13267 article EN Journal of Digestive Diseases 2024-03-01

We aimed to investigate the role of forkhead box O1 (FoxO1) inhibitor AS1842856 (AS) in nonalcoholic steatohepatitis (NASH) mice and potential mechanisms.

10.1111/1751-2980.13306 article EN Journal of Digestive Diseases 2024-07-01

Colorectal endoscopic submucosal dissection (ESD) is a technically demanding operation with long learning curve. The aim of this study was to determine whether orthodontic rubber band (ORB)-assisted colorectal ESD could improve the trainees' curve as it shown shorten procedure time in trainees and experts.

10.14309/ajg.0000000000003239 article EN cc-by-nc-nd The American Journal of Gastroenterology 2024-11-26

Background: Chromogranin B (CgB) is increased in heart failure and proportionate to disease severity. We investigated whether circulating CgB level associated with left ventricular (LV) functional recovery potential after successful recanalization of chronic total occlusion (CTO). Methods: Serum levels were assayed 53 patients stable angina LV [an absolute increase ejection fraction (EF) ≥5%] age- sex-matched non-recovery controls CTO during 12-month follow-up. Results: found that was...

10.3389/fcvm.2021.756594 article EN cc-by Frontiers in Cardiovascular Medicine 2021-12-24

Aberrant changes in endothelial phenotype and morphology are considered to be initial events the pathogenesis of atherosclerosis. Direct observation intact endothelium will provide valuable information for understanding cellular molecular dysfunctional cells. Here, we describe a modified en face immunofluorescence staining technique which enables scientists obtain clear images surface analyze molecule expression patterns situ. The method is simple reliable observing entire monolayer at...

10.3791/59325-v article EN Journal of Visualized Experiments 2019-08-20

Abstract Background: Due to advances in medical treatments, a substantial proportion of heart failure (HF) patients with reduced left ventricular ejection fraction (EF, HFrEF) have experienced partial or complete recovery EF, termed HFrecEF, and markedly improved clinical outcomes. In the present study, we sought investigate relationship between glycemic control incidence HFrecEF type 2 diabetes mellitus (T2DM). Methods: A total 385 T2DM HFrEF were consecutively enrolled. Follow-up...

10.21203/rs.3.rs-1288937/v1 preprint EN cc-by Research Square (Research Square) 2022-02-01
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