Chih-Ling Zao

ORCID: 0000-0003-2221-3827
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About
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Research Areas
  • Animal Virus Infections Studies
  • Viral Infections and Immunology Research
  • Trypanosoma species research and implications
  • Viral gastroenteritis research and epidemiology
  • Cytomegalovirus and herpesvirus research
  • Research on Leishmaniasis Studies
  • Herpesvirus Infections and Treatments
  • HIV Research and Treatment
  • Parasitic Infections and Diagnostics
  • Virology and Viral Diseases
  • Immunodeficiency and Autoimmune Disorders
  • Insect symbiosis and bacterial influences
  • Respiratory viral infections research
  • Monoclonal and Polyclonal Antibodies Research
  • Chromosomal and Genetic Variations
  • Plant Virus Research Studies

University of Nevada, Las Vegas
2019

RF Laboratories (United States)
2011

National Taiwan University
1999-2001

Abstract OBJECTIVE To evaluate clinical, serologic, parasitological, and histologic outcomes of dogs with naturally occurring Trypanosoma cruzi infection treated for 12 months amiodarone itraconazole. ANIMALS 121 from southern Texas Louisiana. PROCEDURES Treatment group (n = 105) received a combination hydrochloride (approx 7.5 mg/kg [3.4 mg/lb], PO, q 24 h, or without loading dosage protocol) itraconazole 10 [4.5 adjusted to maintain plasma concentration 1 2 μg/mL) months. Control 16) no...

10.2460/javma.255.3.317 article EN Journal of the American Veterinary Medical Association 2019-07-12

ABSTRACT The transmembrane glycoprotein NSP4 functions as a viral enterotoxin capable of inducing diarrhea in young mice. It has been suggested that may be key determinant rotavirus pathogenicity and target for vaccine development. Twenty two G1P[6] rotaviruses from babies with without were comparatively analyzed along reference strains another 22 Taiwanese human G P combination types different the type. sequence variations genes studied by direct sequencing analysis amplicons reverse...

10.1128/jcm.38.12.4471-4477.2000 article EN Journal of Clinical Microbiology 2000-12-01

G2 rotavirus was prevalent in a 1993 epidemic of acute gastroenteritis Taiwan. In this study, the genetic relationship among strains analysed. The VP7 genes were amplified and sequenced. Except for one strain isolated 1981, nucleotide sequences most rotaviruses very similar (identity > 97%) closely related to that Japanese reference strain, S2. relatedness analysed further by RNA-RNA hybridization. genomes major did not hybridize well with those previous seasons RNA segments 1, 6 7. Partial...

10.1099/0022-1317-80-6-1407 article EN Journal of General Virology 1999-06-01

G1P[6] rotaviruses were demonstrated previously to be associated with the neonatal nursery outbreak of gastroenteritis in Changhua Christian Hospital that is located central region Taiwan, from September 1994 May 1995. Meanwhile, detected children hospitalized for acute gastroenteritis. Our study characterizes by using genetic approaches. Nucleotide sequence analysis revealed VP7 genes distinct those strains circulating community. The recovered closely related another strain northern Taiwan...

10.1002/1096-9071(200104)63:4<311::aid-jmv1007>3.0.co;2-s article EN Journal of Medical Virology 2001-01-01

A new simian retrovirus (SRV) subtype was discovered in China and the USA from Cambodian-origin cynomolgus monkeys. Histopathological examination necropsied animals showed multifocal lymphoplasmacystic histocytic inflammation. The complete genome sequences demonstrated that US virus isolates were nearly identical (99.91–99.93 %) differed only slightly (99.13–99.16 % identical) isolate. Phylogenetic analysis formed a distinct branch of SRV-1 through -7, therefore named this subtype, SRV-8....

10.1099/jgv.0.000601 article EN Journal of General Virology 2016-09-08

To date, there is no clear standard to monitor drug treatment for canine Chagas disease. We used 2 real-time PCR (rtPCR) assays targeting Trypanosoma cruzi kinetoplast DNA (kDNA) and nuclear satellite (nDNA) detect T. in whole blood. Samples were collected randomly from 131 untreated dogs with unknown infection status Texas. The kDNA-based rtPCR was slightly more sensitive (diagnostic sensitivity of kDNA = 49% vs. nDNA 44%; p 0.5732) but less specific specificity 96% 97%; > 0.9999) than the...

10.1177/1040638719868508 article EN Journal of Veterinary Diagnostic Investigation 2019-08-05
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