A5046300933- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Gut microbiota and health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Berberine and alkaloids research
- Diabetes Treatment and Management
- Retinal Diseases and Treatments
- Chronic Kidney Disease and Diabetes
- Diet and metabolism studies
- Lipid metabolism and disorders
- COVID-19 Clinical Research Studies
- Metabolism, Diabetes, and Cancer
- Pharmacology and Obesity Treatment
- Natural Antidiabetic Agents Studies
- Retinal Imaging and Analysis
- Plant-based Medicinal Research
- Long-Term Effects of COVID-19
- Tryptophan and brain disorders
- Neurological Disease Mechanisms and Treatments
- SARS-CoV-2 and COVID-19 Research
- Diabetes Management and Research
- Chromatography in Natural Products
- Pain Mechanisms and Treatments
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Guang’anmen Hospital
2016-2025
China Academy of Chinese Medical Sciences
2009-2023
Changchun University of Chinese Medicine
2023
Inserm
2017
Christie's
2017
Creative Commons
2017
National Natural Science Foundation of China
2017
Beijing University of Chinese Medicine
2013
Abstract The gut microbiota is hypothesized to have a critical role in metabolic diseases, including type 2 diabetes (T2D). A traditional Chinese herbal formula, Gegen Qinlian Decoction (GQD), can alleviate T2D. To find out whether GQD modulates the composition of during T2D treatment, 187 patients were randomly allocated receive high (HD, n=44), moderate (MD, n=52), low dose (LD, n=50) or placebo (n=41) for 12 weeks double-blinded trial. Patients who received HD MD demonstrated significant...
ABSTRACT Accumulating evidence implicates gut microbiota as promising targets for the treatment of type 2 diabetes mellitus (T2DM). With a randomized clinical trial, we tested hypothesis that alteration may be involved in alleviation T2DM with hyperlipidemia by metformin and specifically designed herbal formula (AMC). Four hundred fifty patients were randomly assigned to either metformin- or AMC-treated group. After 12 weeks treatment, 100 selected from each group assessed improvement. The...
Living in a prediabetes state significantly increases patient's risk for both diabetes and cardiovascular disease. Tianqi capsule, containing 10 Chinese herbal medicines, is used China the treatment of type 2 mellitus (T2DM).The purpose this study was to assess whether prevented T2DM subjects with impaired glucose tolerance (IGT) over course 12-month treatment.Individuals IGT were randomly allocated double-blind manner receive (n = 210) or placebo 12 months. Oral tests conducted every 3...
Metformin plays an important role in diabetes treatment. Studies have shown that the combined use of oral hypoglycemic medications is more effective than metformin monotherapy. In this double-blind, randomized, placebo-controlled, multicenter trial, we evaluated whether Jinlida, a Chinese herbal medicine, enhances glycemic control type 2 patients whose HbA1c was ineffectively controlled with alone.
Aim TM81 (or Tang‐Min‐Ling‐Wan) is a Chinese medicine. Previous studies suggested that this medicine effective for treating type 2 diabetes. This controlled trial evaluated the safety and effectiveness of in treatment diabetic patients. Methods study was large‐scale clinical to evaluate on After 2‐week run‐in period, 480 overweight early‐stage patients [35–65 years old, HbA1c ≥ 7.0%, fasting plasma glucose ( FPG ) 7.0–13.9 mM or h PG > 11.1 , body mass index BMI 24 kg/m ] were enrolled....
Abstract: Diabetes mellitus (DM) was one of the most severe public health problems that affected nearly 463 million adults around world. In addition to insulin and oral hypoglycemic agents, traditional Chinese medicine (TCM) an effective alternative therapy for diabetes its complications, it had been widely used in Pan-Pacific region, especially Southeast Asia, however, TCM lacked specialized standards care DM past, which limited clinical efficacy diabetes. Since March 2017, Endocrinology...
The ZaoRenDiHuang (ZRDH) capsule is widely used in clinical practice and has significant therapeutic effects on insomnia. However, its active ingredients mechanisms of action for insomnia remain unknown. In this study, network pharmacology was employed to elucidate the potential anti-insomnia ZRDH.The ZRDH were obtained from Traditional Chinese Medicine Systems Pharmacology Database. Possible targets predicted using SwissTargetPrediction tools. insomnia-related identified target database,...
Objective: To conduct a randomized controlled clinical trial to evaluate the efficacy and prognostic value of Jinhua Qinggan granules in patients with confirmed suspected coronavirus disease 2019 (COVID-19). Methods: A total 123 COVID-19 participated this were randomly divided into Western medicine groups. For 14 days, group was treated antiviral drugs, drugs alone. We collected information on symptoms, aggravation rates, negative conversion rates nucleic acids patients, observed effects...