A5101456126- Nitric Oxide and Endothelin Effects
- Telomeres, Telomerase, and Senescence
- Cancer-related molecular mechanisms research
- Adipokines, Inflammation, and Metabolic Diseases
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Adipose Tissue and Metabolism
- Dietary Effects on Health
- RNA Interference and Gene Delivery
- Non-Invasive Vital Sign Monitoring
- Cancer, Lipids, and Metabolism
- Wine Industry and Tourism
- Antioxidant Activity and Oxidative Stress
- Effects of Radiation Exposure
- Eicosanoids and Hypertension Pharmacology
- Mitochondrial Function and Pathology
- Mesenchymal stem cell research
- Redox biology and oxidative stress
- Ferroptosis and cancer prognosis
- Cancer Research and Treatments
- Oral health in cancer treatment
- Immunotherapy and Immune Responses
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Guang’anmen Hospital
2019-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Jinan University
2024
China Academy of Chinese Medical Sciences
2019
Cincinnati Children's Hospital Medical Center
2005-2016
University of Cincinnati
2006
University of Cincinnati Medical Center
2005
Duke University
2004
Duke University Hospital
2002-2003
Duke Medical Center
2002-2003
Abstract: Diabetes mellitus (DM) was one of the most severe public health problems that affected nearly 463 million adults around world. In addition to insulin and oral hypoglycemic agents, traditional Chinese medicine (TCM) an effective alternative therapy for diabetes its complications, it had been widely used in Pan-Pacific region, especially Southeast Asia, however, TCM lacked specialized standards care DM past, which limited clinical efficacy diabetes. Since March 2017, Endocrinology...
Arteriosclerosis plays a significant role as one of the key pathological mechanisms underlying Diabetic Kidney Disease (DKD). The estimated Pulse Wave Velocity (ePWV) is used to assess arteriosclerosis, and considered potential clinical surrogate for pulse wave velocity. There are no studies on ePWV in relation DKD. Our research represents first embark explore relationship between In this cross-sectional analysis, we collected data from cohort 4,296 hospitalized Chinese patients....
Nitric oxide (NO), endogenously synthesized by inducible NO synthase (iNOS), serves antioxidant and antiapoptotic functions in settings characterized oxidative stress proinflammatory cytokines such as sepsis shock. However, the redox-sensitive mechanisms regulating hepatocyte expression of iNOS are largely unknown. In interleukin-1β (IL-1β)-stimulated hepatocytes exposed to superoxide, we demonstrate that nuclear factor-4α (HNF-4α) acts an activator redox-associated at level protein, mRNA,...
Abstract In endotoxin (LPS)-mediated states of sepsis, inducible NO synthase expression and production are associated with molecular regulatory functions that determine the host inflammatory response. inhibits cellular respiration mitochondrial electron transport by inhibition cytochrome c oxidase (CcO) activity. CcO is terminal complex respiratory chain, responsible for 90% oxygen consumption essential energy production. Subunit 1 (CcO I) considered to be most critical 13 component...
Human CD34+ hematopoietic stem and progenitor cells (HSPC) expressing fusion protein AML1-ETO (AE), generated by the t(8;21)(q22;q22) rearrangement, manifest enhanced self-renewal dysregulated differentiation without leukemic transformation, representing a pre-leukemia stage. Enabling replicative immortalization via telomerase reactivation is crucial step in cancer development. However, AE expression alone not sufficient to maintain high activity immortalize human HSPC cells, which may...
In recent years, the low-alcohol beverage industry in China has experienced a surge investment. This study utilizes questionnaire survey method to investigate behavior of 601 college student consumers Guangdong Province, China. Employing Rank Sum Ratio (RSR) comprehensive evaluation method, consumer group is classified into five categories based on their purchasing power. Statistical and machine learning methods are subsequently employed analyze preferences habits related appearance...
<title>Abstract</title> Objective Arteriosclerosis is the pathological basis for Diabetic Kidney Disease (DKD). The estimated Pulse Wave Velocity (ePWV) used to assess arteriosclerosis, and considered a potential clinical surrogate pulse wave velocity. There are no studies on ePWV in relation DKD. Our research represents first embark explore relationship between Methods In this cross-sectional analysis, we collected data from cohort of 4,296 hospitalized Chinese patients....