Xinshen Li

ORCID: 0000-0003-2233-7918
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About
Contact & Profiles
Research Areas
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Lipid metabolism and disorders
  • Nematode management and characterization studies
  • Plant Disease Management Techniques
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Respiratory Support and Mechanisms
  • Circular RNAs in diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Mycorrhizal Fungi and Plant Interactions
  • Immune cells in cancer
  • Plant Disease Resistance and Genetics
  • Intracranial Aneurysms: Treatment and Complications
  • Advanced biosensing and bioanalysis techniques
  • Entomopathogenic Microorganisms in Pest Control
  • RNA Interference and Gene Delivery
  • Neurosurgical Procedures and Complications
  • Plant Pathogenic Bacteria Studies
  • RNA modifications and cancer
  • Plant Virus Research Studies
  • Plant and Fungal Interactions Research
  • Vascular Malformations Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cancer-related molecular mechanisms research

Mianyang Third People's Hospital
2024

Sichuan University
2023

West China Hospital of Sichuan University
2023

Jiangxi Academy of Agricultural Sciences
2018-2022

Institute of Plant Protection
2018-2022

Affiliated Hospital of Southwest Medical University
2017-2018

State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2012

Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is closely associated with neuroinflammation. Microglial activation an early event that leads to neuroinflammation after SAH. Peli1 E3 ubiquitin ligase mediates the induction of pro-inflammatory cytokines in microglia. Here we report contributions SAH mediated pathology. An model was induced by endovascular perforation adult male C57BL/6J mice. markedly mice brains a time-dependent manner and predominantly expressed...

10.3389/fnmol.2017.00398 article EN cc-by Frontiers in Molecular Neuroscience 2017-11-29

Subarachnoid haemorrhage (SAH) is a fatal neurovascular disease following cerebral aneurysm rupture with high morbidity and mortality rates. Long non-coding RNAs (lncRNAs) are type of mammalian genome transcript, abundantly expressed in the brain involved many nervous system diseases. However, little currently known regarding influence lncRNAs early injury (EBI) after SAH. This study analysed expression profiles mRNAs SAH tissues mice using high-throughput sequencing. The results showed...

10.1038/srep46577 article EN cc-by Scientific Reports 2017-04-18

COG1410, a mimetic peptide derived from the apolipoprotein E (apoE) receptor binding region, exerts positive effect on neurological deficits in early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH). Currently neuroprotective of COG1410 includes inhibiting BBB disruption, reducing neuronal apoptosis and neuroinflammation. However, mechanism to subcellular organelles disorder have not been fully investigated. As main pathway for recycling long-lived proteins damaged...

10.3389/fnins.2018.00127 article EN cc-by Frontiers in Neuroscience 2018-03-04

Wilt is one the most serious soil-born fungal diseases of Chinese yam (

10.1094/pdis-12-21-2796-pdn article EN Plant Disease 2022-11-03

Objective To explore the altered expression of circular RNA (circRNA) and mRNA in mouse cortex early phase subarachnoid hemorrhage (SAH) possible biological functions circRNA brain injury (EBI). Methods A total 18 C57BL/6J male mice were randomly divided into a sham SAH group (n=9). models prepared by endovascular perforation. Total RNAs samples extracted to construct cDNA library 24 h after operation. RNA-sequencing (RNA-seq) was carried out HiSeqTM 2500 User Guide followed RT-qPCR...

10.3760/cma.j.issn.1671-8925.2018.05.001 article EN Chinese Journal of Neuromedicine 2018-05-15

Root-knot nematode disease seriously threatens the production of Rui yams, making it important to explore effective management strategies, including optimal time for control and efficient application techniques. In this study, we monitored dynamics a root-knot J2 population in soil using field sampling; moreover, investigated sampling visual situ device based on identifying species nematodes yams. Additionally, experiments pertaining techniques were conducted Ruichang Nanchang. This is first...

10.3390/agriculture12122031 article EN cc-by Agriculture 2022-11-28
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