- Cloud Data Security Solutions
- Cryptography and Data Security
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Autism Spectrum Disorder Research
- Neurogenesis and neuroplasticity mechanisms
- Nerve injury and regeneration
- Privacy-Preserving Technologies in Data
- Rheumatoid Arthritis Research and Therapies
- Immunodeficiency and Autoimmune Disorders
- Advanced Data Storage Technologies
- Blockchain Technology Applications and Security
- SARS-CoV-2 and COVID-19 Research
- T-cell and B-cell Immunology
- Dementia and Cognitive Impairment Research
- Tuberculosis Research and Epidemiology
- Head and Neck Cancer Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Monoclonal and Polyclonal Antibodies Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neural and Behavioral Psychology Studies
- TGF-β signaling in diseases
- Brain Metastases and Treatment
Ippokrateio General Hospital of Thessaloniki
2025
IMDEA Software
2023-2024
National and Kapodistrian University of Athens
2009-2023
Hippocration General Hospital
2020-2023
EURECOM
2016-2020
Brain-derived neurotrophic factor signals and dopaminergic function in the brain are strongly associated, research on BDNF schizophrenia may enhance our insights pathophysiological mechanisms of this disease. In present study we aimed to investigate possible association between serum levels schizophrenic relapses differential effects treatment with typical atypical antipsychotics same group patients. We measured 47 patients during a relapse again 6 weeks after administration antipsychotic...
The Stroop Test is a quick and frequently used measure in screening for brain damage, dysfunction of selective attention, cognitive flexibility. purpose the present study to provide normative data Trenerry's Neuropsychological Screening (SNST) sample 605 healthy Greek participants (age range: 18-84 years, education 6-18 years). Results revealed that age significantly contributed SNST scores, accounting significant proportion variance time needed complete color task interference Color-Word...
Abstract Background We aimed to report on the efficacy and safety of elective switching from intravenously (IV) subcutaneously (SC) administered Infliximab (IFX) in patients with immune mediated diseases. Methods This was a multicenter retrospective study which we analyzed data collected consecutive diseases treated hospital setting. Each department considered center overall, 8 gastroenterology departments, 6 rheumatology departments 1 dermatology 13 Greek hospitals, that are all referral...
This paper addresses the problem of data retrievability in cloud computing systems performing deduplication to optimize their space savings: While there exist a number proof (PoR) solutions that guarantee storage correctness with cryptographic means, these unfortunately come at odds technology. To reconcile proofs file-based cross-user deduplication, we propose message-locked PoR approach whereby effect on duplicate is identical and depends value segment, only. As concept, describe two...
We introduce POROS that is a new solution for proof of data reliability. In addition to the integrity outsourced cloud storage system, reliability assures customers provider (CSP) has provisioned sufficient amounts redundant information along with original segments be able guarantee maintenance in face corruption. spite meeting basic service requirement, placement repair capability at CSP raises challenging issue respect design scheme. Existing schemes like Proof Data Possession (PDP) and...
Proofs of data reliability are cryptographic protocols that provide assurance to a user cloud storage system correctly stores her and has provisioned sufficient redundancy be able guarantee reliable service. In this paper, we consider distributed systems make use erasure codes reliability. We propose novel proof scheme, named PORTOS, on the one hand guarantees retrieval outsourced in their entirety through proofs possession other ensures actual redundancy. PORTOS makes sure is stored at rest...
A contingent payment protocol involves two mutually distrustful parties, a buyer and seller, operating on the same blockchain, digital product, whose ownership is not tracked blockchain (e.g. book). The holds coins transfers them to seller in exchange for product. However, if does hide transaction details, any observer can learn that purchased some product from seller. In this work, we take step further: consider who wishes buy routing via an untrusted mixer. Crucially, require said...
Abstract Background and Aims The role of plasmapheresis in the overall renal survival patients with ANCA-associated vasculitis (AAV) has not been fully elucidated. aim this study is to address whether associated improvement function at 12 months severe manifestations AAV record indications, adverse events treatment characteristics. Method Retrospective, descriptive 28 diagnosed over last five years a tertiary center. Patients were included if they had received therapeutic adjunctive...
Abstract Background and Aims The transforming growth factor-β1 (TGF-β1) is a pleiotropic cytokine, with distinct roles both in fibrosis inflammation acts through the Smad signalling renal injury. We sought expression of TGF-β1/Smad ANCA associated glomerulonephritis (AAGN) we assessed this correlation injury at diagnosis as well progression. Method evaluated immunohistochemical TGF-β1, phosphorylated Smad3 (pSmad3) Smad7 semi-quantitatively quantitatively using computerized image analysis...
Abstract Background and Aims Interstitial inflammatory infiltrates in ANCA associated glomerulonephritis (AAGN) are frequently observed but their correlation to clinicopathological parameters remains elusive. Method Retrospective study of 40 patients with newly diagnosed AAGN. Histological assessments using the presence interstitial cells were performed. Biopsy tissues investigated by CD3, CD20, CD4, CD8, CD68+ (PG-M1), CD138 immunohistochemical staining. We assessed terms clinical,...
Abstract Proofs of Data Reliability are cryptographic protocols that provide assurance to a user cloud storage system correctly stores her data and has provisioned sufficient redundancy be able guarantee reliable service. In this paper, we consider distributed systems make use erasure codes reliability. We propose two novel Proof schemes, namely POROS PORTOS, on the one hand guarantees retrieval outsourced in their entirety through proofs possession other ensures actual redundancy. As...
Abstract BACKGROUND AND AIMS Immunosuppressed patients are in general less likely to achieve a detectable antibody response SARS-CoV-2 after the primary doses of vaccine administration. However, there limited data for effect third booster dose this patient population, especially those with vasculitides and renal involvement treated rituximab (RTX). METHOD We retrospectively assessed responses vaccination, completion series (two doses) dose, involvement. IgG antibodies spike protein S1...
Abstract BACKGROUND AND AIMS Transforming growth factor-β1 (TGF-β1) has long been considered as a potent, multifunctional cytokine that is involved in the pathogenesis of fibrosis and inflammation, which acts through Smad signaling renal pathology. We intended to investigate expression TGF-β1/Smad3 glomerulonephritis (GN) assess its role risk factor for progression chronic kidney disease (CKD). METHOD evaluated immunohistochemical TGF-β1, phosphorylated Smad3 (pSmad3) Smad7...
Abstract Background and Aims The role of complement activation, mainly alternative system, has been recently proposed to play an important in the pathogenesis ANCA associated vasculitis (AAV). Real life data assessing its predictive renal outcomes are limited. In this study, we evaluated value serum kidney deposited C3 predicting patients with AAV. Method retrospective AAV were categorized according their baseline levels as hypo- or normo-complementemic those positive negative biopsy...
Abstract Background and Aims There is limited guidance evidence for the ideal duration of maintenance treatment in ANCA-associated vasculitis (AAV) with rituximab (RTX). This study aimed to describe efficacy safety long-term RTX, a cohort patients AAV. Method Retrospective, descriptive 62 We included 42 patients, who received RTX newly diagnosed or relapsed disease. recorded duration, dosage, adverse events (infections, infusion-related events, relapses, late onset leukopenia, malignancy...