A5047035896- Chronic Disease Management Strategies
- Frailty in Older Adults
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Dementia and Cognitive Impairment Research
- Diabetes Management and Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Primary Care and Health Outcomes
- Nutritional Studies and Diet
- Diabetes Management and Research
- Palliative Care and End-of-Life Issues
- Heart Failure Treatment and Management
- Health disparities and outcomes
- Balance, Gait, and Falls Prevention
- Healthcare Policy and Management
- Diabetic Foot Ulcer Assessment and Management
- Blood Pressure and Hypertension Studies
- Diabetes Treatment and Management
- Cardiovascular Health and Risk Factors
- Intensive Care Unit Cognitive Disorders
- Cardiac Valve Diseases and Treatments
- Health, Environment, Cognitive Aging
- Obesity, Physical Activity, Diet
- Aging and Gerontology Research
Michigan United
2003-2024
National Committee for Quality Assurance
2020-2022
New York University
2013-2022
NYU Langone Health
2013-2022
Sprint (United States)
2021
SPRINT
2021
Ann Arbor Center for Independent Living
2009-2020
University of Michigan
2003-2016
American Geriatrics Society
2014
John A. Hartford Foundation
2014
BackgroundFrailty in older adults, defined as a constellation of signs and symptoms, is associated with abnormal levels individual physiological systems. We tested the hypothesis that it critical mass systems frailty, over above status each system, relationship nonlinear.
Inouye, Sharon K. MD, MPH; Robinson, Thomas MS, FACS; Blaum, Caroline MS; Busby-Whitehead, Jan CMD, AGSF; Boustani, Malaz Chalian, Ara MD; Deiner, Stacie Fick, Donna PhD, RN, FGSA, FAAN; Hutchison, Lisa PharmD; Johanning, Jason Katlic, Mark Kempton, James; Kennedy, Maura MD. Kimchi, Eyal Ko, Cliff Leung, Jacqueline Mattison, Melissa; Mohanty, Sanjay Nana, Arvind Needham, Dale PhD; Neufeld, Karin Richter, Holly MD The American Geriatrics Society Expert Panel on Postoperative Delirium in Older...
Objectives: To determine whether obesity is associated with the frailty phenotype and, if so, comorbid conditions or inflammatory markers explain this association. Design: Cross‐sectional analysis of baseline data from Women's Health and Aging Studies I (1992) II (1994), complementary population‐based studies. Setting: Twelve contiguous ZIP code areas in Baltimore, Maryland. Participants: Five hundred ninety‐nine community‐dwelling women aged 70 to 79 a body mass index (BMI) greater than...
Our research group has previously shown that the geriatric syndrome of frailty is associated with features metabolic (MetS) on cross-sectional analysis.To test whether MetS and its physiologic determinants-insulin resistance as measured by homeostasis model assessment score (IR-HOMA), increased inflammation coagulation factor levels, elevated blood pressure-are incident frailty, we studied a subcohort participants from Cardiovascular Health Study observed 1989/1990 through 1998/1999: 3141...
Background: Geriatric conditions, such as incontinence and falling, are not part of the traditional disease model medicine may be overlooked in care older adults. The prevalence geriatric conditions their effect on health disability adults has been investigated population-based samples. Objective: To investigate association with dependency activities daily living by using nationally representative data. Design: Cross-sectional analysis. Setting: Health Retirement Study survey administered...
To operationalize and compare three models of frailty, each representing a distinct theoretical view frailty: as deficiencies in function (Functional Domains model), an index health burden (Burden biological syndrome (Biologic Syndrome model).Cross-sectional analysis.2004 wave the Health Retirement Study, nationally representative, longitudinal interview survey.Adults aged 65 older (N=11,113) living community nursing homes United States.The outcome measure was presence defined according to...
Caring for older adults with multiple chronic conditions (MCCs) is challenging. The American Geriatrics Society (AGS) previously developed AGS Guiding Principles the Care of Older Adults With Multimorbidity using a systematic review literature and consensus. objective current work was to translate these principles into framework Actions accompanying Action Steps decision making clinicians who provide both primary specialty care people MCCs. A group geriatricians, cardiologists, generalists:...
Little is known about long-term recovery from severe COVID-19 disease. Here, we characterize overall health, physical and mental health of patients 1 month after discharge for COVID-19. This was a prospective single system observational cohort study ≥ 18 years hospitalized with laboratory-confirmed disease who required at least 6 l oxygen during admission, had intact baseline cognitive functional status, were discharged alive. Participants enrolled between 30 40 days discharge. Outcomes...
To analyze the co-occurrence, in adults aged 65 and older, of five conditions that are highly prevalent, lead to substantial morbidity, have evidence-based guidelines for management well-developed measures medical care quality.Secondary data analysis 2004 wave Health Retirement Study (HRS).Nationally representative health interview survey.Respondents HRS older.Self-reported presence index (three chronic diseases (coronary artery disease, congestive heart failure, diabetes mellitus) two...
<h3>Background</h3> Mechanisms for racial/ethnic disparities in glycemic control are poorly understood. <h3>Methods</h3> A nationally representative sample of 1901 respondents 55 years or older with diabetes mellitus completed a mailed survey 2003; 1233 valid at-home hemoglobin A<sub>1c</sub>(HbA<sub>1c</sub>) kits. We constructed multivariate regression models weights to examine differences HbA<sub>1c</sub>control and explore the association HbA<sub>1c</sub>level sociodemographic clinical...
Micronutrient deficiencies are common among older adults. We hypothesized that low serum micronutrient concentrations were predictive of frailty disabled women living in the community.We studied 766 women, aged 65 and older, from Women's Health Aging Study I, a population-based study moderately to severely community-dwelling Baltimore, Maryland. Serum vitamins A, D, E, B(6), B(12), carotenoids, folate, zinc, selenium measured at baseline. Frailty status was determined baseline during annual...
OBJECTIVE—To elucidate the role of diabetes-related impairments and comorbidities in association between diabetes physical disability, this study examined lower extremity function a sample disabled older women. RESEARCH DESIGN AND METHODS—Cross-sectional analysis 1,002 women (aged ≥65 years) enrolled Women’s Health Aging Study (one-third most total community-dwelling population). Diabetes other medical conditions were ascertained by standard criteria that used multiple sources information....
Background. The aim of this study was to determine whether older disabled women with diabetes have an increased risk falls compared without and identify fall factors among high-risk subgroup patients.
Background. Undernutrition in nursing home residents is a significant and possibly modifiable public health problem. We evaluated the hypothesis that some potentially factors are associated with resident undernutrition. Methods. This study cross-sectional, secondary data analysis of 6,832 community sampled from 202 homes 7 states. Data were Minimum Set (MDS), an HCFA-mandated assessment instrument used U.S. homes. Two dependent variables represented undernutrition: (a) low body mass index...
While statin therapy for primary cardiovascular prevention has been associated with reductions in morbidity, the effect on all-cause mortality variable. There is little evidence to guide use of statins adults 75 years and older.To examine treatment among aged 65 74 older when used Lipid-Lowering Trial (LLT) component Antihypertensive Treatment Prevent Heart Attack (ALLHAT-LLT).Post hoc secondary data analyses were conducted participants without atherosclerotic disease; 2867 ambulatory...
Objectives To determine the degree to which hyperglycemia predicts development of frailty and lower extremity mobility limitations. Design Secondary data analysis longitudinal collected in a prospective cohort study. Setting B altimore, M aryland. Participants Three hundred twenty‐nine women from W omen's H ealth A ging S tudy II aged 70 79 at baseline who had all variables needed for analysis. Measurements Glycosylated hemoglobin ( b 1c) baseline, categorized as less than 5.5%, 5.5% 5.9%,...
To develop a values-based, clinically feasible process to help older adults identify health priorities that can guide clinical decision-making.Prospective development and feasibility study.Primary care practice in Connecticut.Older with 3 or more conditions taking 10 medications (N=64).The team of patients, caregivers, clinicians used user-centered design framework-ideate → prototype test →redesign-to refine the value-based patient medical record template trained clinician facilitators.We...
Objective. We investigated the relationship of micronutrient deficiencies with frailty syndrome in older women living community.
Objectives To determine the prevalence of cognitive impairment in older adults with heart failure ( HF ). Design Cross‐sectional analysis 2004 wave nationally representative H ealth and R etirement S tudy linked to 2002 M edicare administrative claims. Setting United States, community. Participants Six thousand one hundred eighty‐nine individuals aged 67 older. Measurements An algorithm was developed using a combination self‐ proxy report problem presence or more claims files standard...
To determine whether hyperglycemia is related to prevalent frailty status in older women.