A5101397735- Craniofacial Disorders and Treatments
- Dental Implant Techniques and Outcomes
- Cleft Lip and Palate Research
- Heart Failure Treatment and Management
- Bone Tissue Engineering Materials
- Reconstructive Surgery and Microvascular Techniques
- Cardiovascular Function and Risk Factors
- Tracheal and airway disorders
- Facial Trauma and Fracture Management
- Reconstructive Facial Surgery Techniques
- Peptidase Inhibition and Analysis
- Cardiac Imaging and Diagnostics
- Temporomandibular Joint Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Ear and Head Tumors
- Orthodontics and Dentofacial Orthopedics
- Nasal Surgery and Airway Studies
- Esophageal and GI Pathology
- Tumors and Oncological Cases
- Restless Legs Syndrome Research
- Salivary Gland Tumors Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Hemodynamic Monitoring and Therapy
- Esophageal Cancer Research and Treatment
- Diabetes Treatment and Management
Kogakuin University
2023
Hokkaido Pharmaceutical University
2021
Hokkaido University
2021
University of Tokyo Hospital
2009-2020
Tokyo Medical University
2020
Gunma University
2019
Fukushima Medical University
2015-2019
The University of Tokyo
2009-2016
Background The Get With the Guidelines-Heart Failure ( GWTG - HF ) risk score was developed using American Heart Association program data and predicts in-hospital mortality in patients with acute heart failure (HF). We aimed to clarify prognostic impacts of after discharge. Methods Results examined 1452 HF, who were admitted our hospital discharged treatment, by calculating 7 predetermined variables. divided all subjects into 3 groups according (low, moderate, high groups). plasma B-type...
Background:Insomnia is associated with incident heart failure (HF), but the clinical significance and impact of insomnia on HF remain unclear.Methods Results:Consecutive 1,011 patients admitted for were divided into 2 groups according to presence insomnia: (insomnia group, n=519) without (non-insomnia n=492). We compared (1) cardiac event rates including death worsening HF; (2) underlying background laboratory data, echocardiographic cardiopulmonary exercise test between groups. On...
Serum uric acid is a predictor of cardiovascular mortality in heart failure with reduced ejection fraction. However, the impact on preserved fraction (HFpEF) remains unclear. Here, we investigated association between hyperuricemia and HFpEF patients. Consecutive 424 patients, who were admitted to our hospital for decompensated diagnosed as having HFpEF, divided into two groups based presence (serum ≥7 mg/dl or taking antihyperuricemic agents). We compared patient characteristics,...
We fabricated custom-made artificial bones using three-dimensionally layered manufacturing (3D printing) process, and have applied them to patients with facial deformities. termed this novel bone the "CT-bone". The aim of present study was evaluate middle- long-term safety effectiveness CT-bones after transplantation.The subject areas involved were 23 sites 20 deformities due congenital abnormality, tumor, or trauma. used for augmentation; they evaluated by CT images, minimally 1 year...
It has been recently reported that histamine H2 receptor antagonists (H2RAs) are associated with impairment of ventricular remodeling and incident heart failure. In addition, favorable pleiotropic effects adverse proton pump inhibitors (PPIs) on cardiovascular disease have also reported. We examined the associations acid suppressive therapy using H2RAs or PPIs cardiac mortality in patients failure.In total, 1191 consecutive failure were divided into 3 groups: a non-acid group (n=363), an...
Abstract Background Heart failure (HF) and diabetes mellitus (DM) often co‐exist. Treatment of DM in HF patients is challenging because some therapies for are contraindicated HF. Although previous experimental studies have reported that dipeptidyl peptidase‐4 (DPP‐4) inhibitors improve cardiovascular function, whether DPP‐4 inhibition improves mortality with remains unclear. Therefore, we examined the impact on hospitalized using propensity score analyses. Methods results We performed...
We aimed to investigate the impact of testosterone on prognosis heart failure (HF), as well underlying cardiac function, damage, and exercise capacity. analyzed consecutive 618 men with HF (age 65.9 years). These patients were divided into quartiles based their serum levels total (TT): first (TT > 631 ng/dl, n = 154), second (462 < TT ≤ 155), third (300 462 156), fourth 300 153) quartiles. In Kaplan–Meier analysis (mean 1,281 days), all-cause mortality progressively increased throughout from...
Background:Heart failure (HF) and cancer (CA) are becoming increasingly prevalent as the population ages. We aimed to evaluate prior history occurrence of CA its prognostic impact on HF.
Mammary analog secretory carcinoma (MASC) is a newly described rare malignancy of the salivary glands characterized by an ETS variant 6 (ETV6)-neurotrophic tyrosine kinase receptor type 3 (NTRK3) fusion gene (EN gene).We present case MASC derived from left upper lip in 61-year-old woman. ETV6 rearrangement was detected fluorescence situ hybridization (FISH). The presence EN transcripts verified reverse-transcriptase polymerase chain reaction (RT-PCR) and sequencing PCR products. Accordingly,...
Autologous, allogeneic, and artificial bones are clinically applied as graft materials for bone reconstruction, with each having their own advantages disadvantages. Although various shapes currently available, a product morphology that may be freely modified by operators has not yet been developed. In the present study, we developed full custom-made bone, it to form maxillofacial region. We herein report treatment outcomes.An was prepared on 3-dimensional solid model, data of its shape...
Abstract Recently, there have been remarkable advances in regenerative medicine, and almost all disorders of the oral maxillofacial region could be research targets medicine. Meanwhile, treatment this has well established using biomaterials, prostheses, microsurgery. Therefore, to surpass such a conventional approach as an alternative, medicine should take being less invasive and/or more effective. In report, we present our preclinical clinical on bone cartilage region. Regarding tried...
Objective To determine the relationship between plaque composition and low-density lipoprotein cholesterol (LDL-C), high-density (HDL-C), apolipoprotein B (Apo-B), Apo-A1 using virtual-histology intravascular ultrasound (VH-IVUS). Methods We assessed in patients with stable coronary artery disease (SCD) admitted to our hospital for percutaneous intervention (PCI) November 1, 2012, March 10, 2015. Before PCI, fibrous (FI), fibrofatty (FF), necrotic core (NC), dense calcium (DC) regions were...
The restless legs syndrome (RLS) is a neurological disorder characterized by an irresistible urge to move the or arms for relief of uncomfortable unpleasant sensations. Prevalence and prognostic impact RLS on patients with heart failure (HF) remain unclear. We aimed investigate clinical characteristics HF patients.
There are various techniques for palatoplasty, but no studies of postoperative osteogenesis at the palatal fissure. In cranial and maxillofacial region it is thought to develop from periosteum, so palatoplasty with mucoperiosteal flaps may encourage new bone form We evaluated status in hard palate after on computed tomograms (CT). studied 29 patients (22 boys 7 girls) unilateral cleft lip who had pushback use CT obtained between May 2003 March 2007. Age time operation was recorded. The width...
Short lingual osteotomy is a useful method for the performance of sagittal split ramus involving interference between proximal and distal bone fragments when lateral differences exist in setback distance. However, this procedure occasionally results abnormal fracture nerve injury; expert surgical skill thus required. We herein describe novel technique use an ultrasonic bone-cutting device (Piezosurgery; Mectron Medical Technology, Carasco, Italy) vertical posterior to mandibular foramen....
We used a piece of costal cartilage as cartilaginous strut to correct the upturned nasal tip in patients with bilateral cleft lip. The grafted provides more definition and improves obtuse nasolabial angle. Neither septal nor ear has enough strength shape tip. This method correction consistently produced favorable, long-lasting results adults improved contour younger patients.
Abstract The authors performed a cantilever iliac bone graft for the secondary correction of severe cleft lip–nose deformities after completion growth. For purpose clarifying effects grafts and adverse events with regard to their time course changes this procedure, retrospectively surveyed long-term morphologic in 65 lip, alveolus, palate patients whom were treated (age at surgery: 14–45 years old). All postsurgical documents facial photographs radiologic images reviewed evaluate events....