A5032579268- Systemic Sclerosis and Related Diseases
- SARS-CoV-2 and COVID-19 Research
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- COVID-19 Clinical Research Studies
- Urticaria and Related Conditions
- Systemic Lupus Erythematosus Research
- Food Allergy and Anaphylaxis Research
- Immune Cell Function and Interaction
- Long-Term Effects of COVID-19
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Multiple Sclerosis Research Studies
Ospedale Monaldi
2021
The role of B cells in the pathogenic events leading to relapsing multiple sclerosis (R-MS) has only been recently elucidated. A pivotal step defining this provided by therapeutic efficacy anti-CD20 monoclonal antibodies. Indeed, treatment with can also alter number and function other immune not directly expressing CD20 on their cell surface, whose activities contribute unknown aspects influencing efficacy. We examined phenotype cytotoxic lymphocytes Epstein-Barr virus (EBV)-specific...
In December 2019, a novel coronavirus, “SARS-CoV-2”, was recognized as the cause of coronavirus disease 2019 (COVID-19). Several studies have explored changes and role inflammatory cells cytokines in immunopathogenesis disease, but until today, results been controversial. Based on these premises, we conducted retrospective assessment monocyte intracellular TNF-α expression (iTNF-α) frequencies lymphocyte sub-populations twenty-five patients with moderate/severe COVID-19. We found lymphopenia...
Background. Extracorporeal photopheresis (ECP) has emerged as a prophylactic and therapeutic immunomodulatory option for managing acute rejection in heart transplants (HTx). The underlying mechanisms through which ECP exerts its effects remain under investigation. Regulatory T cells (Treg) are heterogeneous subset of immune lymphocytes that ensure the maintenance tissue homeostasis, avoiding graft rejection. transcription factor forkhead box protein 3 (FoxP3) is an essential molecular marker...