- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Long-Term Effects of COVID-19
- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- COVID-19 Clinical Research Studies
- Neuroscience and Neural Engineering
- Peripheral Nerve Disorders
- Nerve Injury and Rehabilitation
- Epilepsy research and treatment
- Obsessive-Compulsive Spectrum Disorders
- Transcranial Magnetic Stimulation Studies
- Cerebral Palsy and Movement Disorders
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Pain Management and Treatment
- Anesthesia and Pain Management
- Neuroscience and Neuropharmacology Research
- Trigeminal Neuralgia and Treatments
- Pain Mechanisms and Treatments
- SARS-CoV-2 and COVID-19 Research
- Vascular Malformations Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- COVID-19 epidemiological studies
Hospital General de México
2015-2025
Universidad Anáhuac
2013-2025
Hospital Angeles Pedregal
2024-2025
Faculty (United Kingdom)
2024
Stereotaxis (United States)
2024
Universidad Cuauhtémoc San Luis Potosí
2021
Hospital de Especialidades
2019
Centro Medico Nacional Siglo XXI
2019
Instituto Politécnico Nacional
2008-2014
Universidad Panamericana
2011
Summary: Purpose: Our aim was to evaluate the safety and efficacy of electrical stimulation hippocampus in a long‐term follow‐up study, as well its impact on memory performance treatment patients with refractory mesial temporal lobe epilepsy. Methods: Nine were included. All had partial complex seizures, some secondary generalizations. 3‐month‐baseline‐seizure count, after which they underwent bilateral hippocampal diagnostic electrode implantation establish focus laterality location. Three...
Summary: Purpose: Our aim was to evaluate the efficacy of ESCM (electrical stimulation centromedian thalamic nucleus) in treatment generalized seizures Lennox–Gastaut syndrome (LGS) and improvement patient disability. Methods: Thirteen patients with LGS were studied. They had severe tonic–clonic (GTC) atypical absences (AA). All at least a 6‐month baseline before bilateral electrode implantation (CM) nuclei thalamus undergo therapeutic ESCM. Once implanted, electrodes temporally externalized...
OBJECTIVE To evaluate the efficacy of chronic electrical stimulation centromedian thalamic nuclei (ESCM) in treatment difficult-to-control seizures. METHODS Thirteen patients underwent ESCM for periods ranging from 12 to 94 months (mean, 41.2 mo) with electrodes stereotactically placed both and connected internalized systems. Electrode placement was guided by ventriculography confirmed magnetic resonance imaging before systems were internalized. Anatomic electrophysiological confirmation...
Summary: Purpose: The efficacy and safety of cerebellar stimulation (CS) was reevaluated in a double‐blind, randomized controlled pilot study on five patients with medically refractory motor seizures, especially generalized tonic–clonic seizures. Methods: Bilateral modified four‐contact plate electrodes were placed the superomedial surface through two suboccipital burr holes. implanted programmable, battery‐operated stimulator adjusted to 2.0 μC/cm 2 /phase case as anode; at this level, no...
There is a deep need for mortality predictors that allow clinicians to quickly triage patients with severe coronavirus disease 2019 (Covid-19) into intensive care units at the time of hospital admission. Thus, we examined efficacy lymphocyte-to-neutrophil ratio (LNR) and neutrophil-to-monocyte (NMR) as in-hospital death admission in Covid-19. A total 54 Mexican adult Covid-19 met hospitalization criteria were retrospectively enrolled, followed-up daily until discharge or death, then assigned...
In this study the authors used a double-blind protocol to assess efficacy of motor cortex stimulation (MCS) for treating neuropathic pain.Eleven patients with unilateral pain (visual analog scale [VAS] score 8-10) different origins and topography were selected MCS. A 20-contact grid was implanted through craniotomy centered over contralateral painful area. The strip identified using neuroimages, somatosensory evoked potentials, acute electrical stimulation, corticocortical potentials....
Electrical stimulation (ES) of the thalamic centromedian nucleus (CMN) has been proposed as a minimally invasive alternative for treatment difficult-to-control seizures multifocal origin and that are generalized from onset. ES intends to interfere with seizure propagation in non-specific manner through system. By adopting frontal parasagittal approach based on anterior-posterior (AC-PC) commissure intersection, deep brain (DBS) electrodes stereotactically inserted. Electrophysiologic...
In the treatment of tremor and rigidity in patients with Parkinson's disease (PD), prelemniscal radiation (RAPRL), a subthalamic bundle fibers, is an exquisite target that can be visualized easily on ventriculograms. We sought to evaluate effect electrical stimulation RAPRL symptoms signs PD long-term trial determine localization stimulated area by means stereotactic magnetic resonance imaging studies.Ten predominantly one side had tetrapolar electrodes stereotactically oriented through...
Motor cortex stimulation (MCS) is useful to treat patients with neuropathic pain syndromes, unresponsive medical treatment. Complex regional syndrome (CRPS) a segmentary disease treated successfully by spinal cord (SCS). However, CRPS often affects large body segments difficult cover SCS. This study analyzed the MCS efficacy in affecting them. Five of different etiologies underwent small craniotomy for unilateral 20-grid-contact implantation on MC, guided craniometric landmarks....
Tremor and rigidity have been efficiently controlled by electrical stimulation of contralateral prelemniscal radiations (Raprl) in patients with unilateral Parkinson's disease. The present study determines the effect bilateral Raprl a group severe tremor, rigidity, bradykinesia. Five disease (Hoehn Yahr scale, Stage V) underwent stereotactic electrode implantation. Postoperative magnetic resonance imaging studies confirmed their position. Bipolar chronic was performed through contiguous...
We present the results of chronic electrical stimulation hippocampus (ESH) in 9 patients with complex partial seizures and at least 18 months follow-up. The magnetic resonance imaging (MRI) scan was normal 5 while 4 it showed hippocampal sclerosis. seizure frequency ranged from 10 to 50 per month. All were submitted implantation diagnostic 8-contact bilateral depth electrodes determine location epileptic foci. Once focus located, replaced by deep brain (DBS) electrodes. Following DBS, all...
To perform a preliminary study on the effects and safety of bilateral cingulotomy anterior capsulotomy in patients with aggressive behavior.Twenty-three psychiatric showing behavior refractory to conventional treatment were initially evaluated. The subjects clinically selected using Overt Aggression Scale (OAS) Global Assessment Functioning (GAF). Each case was carefully reviewed by Ethics Committee Mexico's General Hospital. Once selection criteria met, stereotactic lesions made...
Objective: The aim of this study is to assess the motor outcomes patients undergoing surgical neurolysis and conduct a comprehensive review existing literature ascertain efficacy utility technique. Surgical procedure designed liberate an injured nerve from scar tissue or adjacent structure, thereby facilitating regeneration in cases brachial plexus neuropathy (BPN). Methods: This presents case series diagnosed with BPN who underwent neurolysis. primary focus was on clinical assessment...
Tuberculomas located in the brainstem are rare entities. This article presents a case study detailing diagnosis and treatment process of patient with pontine tuberculoma, as well literature review tuberculomas pons. A 39-year-old male showed progressive quadriparesis deficits VII, XI, XII cranial nerves. MRI image initially suggested astrocytoma. second biopsy revealed presence acid-fast bacilli. Following six months anti-tuberculous treatment, successful recovery.
Gauss (G) or miliTesla (mT) units measure electromagnetic field (EMF) stimulation. Tarlov Scale (TS) assesses motor impairment, Finger Abduction (FAS) measures finger separation. The objective is to evaluate mobility using EMF in a Sciatic Nerve Injury (SNI) model. SNI caused paresis the right hind limb observe changes male Sprague-Dawley rats (372-529 g) (N = 30). Three groups of (n 10) were created. Control Group (CG) was just injured. experimental EMF-treated two hours day for four weeks...
Background: A diet containing non-caloric sweeteners (NCS) could reduce calorie intake; conversely, some animal studies suggest that NCS consumption may increase functional gastrointestinal disorder symptoms (FGDs). This study aimed to compare the effect of consuming a (c-NCS) versus sweetener-free (NCS-f) on FGDs. Methods: We conducted randomized, controlled, parallel-group using two different diets for five weeks: c-NCS contained 50−100 mg/day NCS, whereas NCS-f had less than 10 NCS. At...
To better define prelemniscal radiations (Raprl) as a target for the control of tremor and rigidity in Parkinson's disease (PD).A total 36 deep brain stimulation (DBS) electrodes were stereotactically implanted Raprl contralateral to extremities be treated. Effects on symptoms evaluated using UPDRS-III before after DBS, significance was determined Wilcoxon test. The location DBS contacts cases with optimum versus suboptimum results Student's t test percentage improvement correlated through...