A5054616410- Gestational Diabetes Research and Management
- Telemedicine and Telehealth Implementation
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 and healthcare impacts
- Childhood Cancer Survivors' Quality of Life
- Adolescent and Pediatric Healthcare
- Birth, Development, and Health
- Lipid metabolism and disorders
- Family Support in Illness
- Hemoglobinopathies and Related Disorders
- Antibiotics Pharmacokinetics and Efficacy
- NF-κB Signaling Pathways
- Bone health and osteoporosis research
- Occupational and environmental lung diseases
- Clinical Laboratory Practices and Quality Control
- Poisoning and overdose treatments
- Effects and risks of endocrine disrupting chemicals
- Eosinophilic Esophagitis
- Global Healthcare and Medical Tourism
- Electrolyte and hormonal disorders
- Diabetes Management and Research
- Healthcare Systems and Public Health
- Blood transfusion and management
- Neonatal Health and Biochemistry
- Heparin-Induced Thrombocytopenia and Thrombosis
University of Alberta
2021-2024
Texas Children's Hospital
2021-2023
Baylor College of Medicine
2021-2023
Creative Commons
2022
Hull York Medical School
2019
Castle Hill Hospital
2019
BACKGROUND: There is a paucity of data regarding the antibody response to SARS-CoV-2 vaccination in children after solid organ transplant.We retrospectively reviewed Anti-Spike IgG antibodies measured following at our pediatric heart transplant (HTx) center.Among patients (median age 17.1 years) whom testing was performed 118 days post-vaccine completion), detected 28 40 (70%) post-HTx recipients level 10.9 AU/ml). Neutropenia, diabetes mellitus, and previous use rituximab were associated...
The COVID-19 pandemic necessitated changes in the delivery of ambulatory care for patients with inflammatory bowel disease (IBD), including transitioning many visits to virtual formats and delaying non-urgent assessments. We aimed evaluate impact on IBD patient from health providers' (HCP) patients' perspectives.We administered a 42-question HCP survey 44-question survey, which evaluated experience satisfaction delays access during first wave pandemic.Surveys were completed by 19.2% (24/125)...
Abstract Background The COVID-19 pandemic is affecting patients and healthcare providers worldwide. During the first wave of pandemic, delivery shifted from in-person to virtual clinics. Non-urgent some emergent procedures, including endoscopies, surgeries, imaging, were delayed limit spread divert resources COVID-19. Aims To assess impact in care IBD Methods A survey study was conducted on care. All had a clinic appointment between March July 2020 at either: University Alberta Hospital or...
Proteinuria is one of the classical criteria for diagnosis pre-eclampsia. The gold standard remains measurement 24-h urine protein which time consuming and prone to preanalytical errors. Random creatinine ratio (UPCR) endorsed by clinical practice guidelines as a faster alternative. aim this study was evaluate correlation between excretion UPCR in identification proteinuria suspected preeclamptic patients.A total 51 women with pre-eclampsia from maternal fetal clinic our institution were...
Abstract Background Vitamin D toxicity is rare in pediatric population. Falsely elevated levels of 25‐hydroxyvitamin have been reported as a major challenge with immunoassay methods for quantifying vitamin metabolites. Case Presentation and Method Here, we present two cases falsely that resulted unnecessary further testing. We also report significant same‐day variation the measurement using Abbott i2000SR immunoassay. Samples were spun twice their values confirmed gold standard liquid...
Atovaquone has traditionally been used as an antiparasitic and antifungal agent, but recent studies have shown its potential anticancer agent. The high variability in atovaquone bioavailability highlights the need for therapeutic drug monitoring, especially pediatric patients. goal of our study was to develop validate performance assay quantify plasma concentrations collected from cancer patients using LC-MS/MS. extracted a 10 µL volume K2-EDTA human solution consisting ACN: EtOH: DMF (8:1:1...
Advanced malignant pleural mesothelioma (MPM) has an extremely poor prognosis with limited chemotherapy options, therefore the identification of new therapeutic targets would aid in disease management. Arachidonic acid is metabolised by cyclooxygenase and lipoxygenase enzymes. The isoenzymes 5-LOX 12-LOX have been implicated carcinogenesis. We aimed to examine protein expression a large retrospective series samples. Further this, vitro cytotoxic effects pathway inhibitors were investigated...
Pediatric hospitals are always challenged by specimen volumes and thus any innovation in this realm is very welcome. With the introduction of Microslide assay pairs, we aimed to evaluate analytical performance Vitros XT MicroSlide pairs on 7600 compared single MicroSlides.Performance characteristics included within-run precision, measurable range, method comparison, interference verification. We six with twelve corresponding slide assays 5600 system.The MicroSlides demonstrated excellent...
Abstract Background In light of the COVID-19 pandemic, gastroenterologists in Alberta moved to virtual care for many clinic visits. As public health situation evolves, it is important evaluate provider satisfaction with during these unprecedented times. Aims To assess healthcare (HCP) pandemic. Methods We administered a 20-item survey that assessed usefulness, ease use, interface qualities, reliability, and overall tools delivery patients gastrointestinal diseases. One hundred twenty-five...
Abstract Background Gestational diabetes mellitus (GDM) is a predictive factor in developing type 2 (T2DM) affected mothers and their offspring. Its prevalence increasing proportionally with the obesity epidemic, affecting 10% of pregnant women 50% which are likely to develop T2DM. Current guidelines by American Diabetes Association College Obstetricians Gynecologists recommend screening at 4–12 weeks 2-hour postpartum glucose tolerance test (OGTT) patients history GDM. However, several...
Abstract Background The COVID-19 pandemic has accelerated the need for healthcare service reform in order to reduce risk of transmission SARS-CoV-2 infection between patients, providers and medical trainees. Gastroenterologists have been challenged adopt virtual consultations accommodate trainees their clinics. Aims To assess impact care on education during Methods A REDCap survey was disseminated among gastroenterology via email. subsection consisted 4 questions pertaining inclusion...