A5023732757- Forensic and Genetic Research
- Wildlife Ecology and Conservation
- Genetic diversity and population structure
- EEG and Brain-Computer Interfaces
- Ecology and Vegetation Dynamics Studies
- Race, Genetics, and Society
- Pleistocene-Era Hominins and Archaeology
- Evolution and Paleontology Studies
- Wildlife-Road Interactions and Conservation
- Genomics and Phylogenetic Studies
- Species Distribution and Climate Change
- Genetic and phenotypic traits in livestock
- Animal Behavior and Reproduction
Brown University
2022-2025
John Brown University
2024
Individual-based simulation has become an increasingly crucial tool for many fields of population biology. However, continuous geography is important to applications, and implementing realistic stable simulations in space presents a variety difficulties, from modeling choices computational efficiency. This paper aims be practical guide spatial simulation, helping researchers implement individual-based avoid common pitfalls. To do this, we delve into mechanisms mating, reproduction,...
ABSTRACT Individual‐based simulation has become an increasingly crucial tool for many fields of population biology. However, continuous geography is important to applications, and implementing realistic stable simulations in space presents a variety difficulties, from modeling choices computational efficiency. This paper aims be practical guide spatial simulation, helping researchers implement individual‐based avoid common pitfalls. To do this, we delve into mechanisms mating, reproduction,...
Evidence of interbreeding between archaic hominins and humans comes from methods that infer the locations segments haplotypes, or ‘archaic coverage’ using genomes people living today. As more estimates coverage have emerged, it has become clear most this is found on autosomes— very little retained chromosome X. Here, we summarize published autosomes X extant human samples. We find average 7 times than X, identify broad continental patterns in ratio: greatest European samples, least South...
Abstract We study the gene MUC19, for which modern humans carry a Denisovan-like haplotype. MUC19 is mucin, glycoprotein that forms gels with various biological functions. find diagnostic variants haplotype at high frequencies in admixed Latin American individuals among global populations, and highest frequency 23 ancient Indigenous individuals, all predating population admixture Europeans Africans. carries higher copy number of 30 base-pair variable tandem repeat, numbers this repeat are...
The distributed architecture of the cortex poses a fundamental challenge for reinforcement learning: how to assign credit specifically regions that contribute successful behavior? Cortical neurons can be driven by both global reinforcers, like rewards, and local sensory features, making it difficult disentangle these influences. To address this, we investigated cortical learning manipulating reward-predictive modality during tasks, while monitoring key regulators activity-local inhibitory...
Abstract Evidence of interbreeding between archaic hominins and humans comes from methods that infer the locations segments haplotypes, or ‘archaic coverage’ using genomes people living today. As more estimates coverage have emerged, it has become clear most this is found on autosomes— very little retained chromosome X. Here, we summarize published autosomes X extant human samples. We find average 7.9 times than X, identify broad continental patterns in ratio: greatest American samples,...