- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Dermatological and COVID-19 studies
- Monoclonal and Polyclonal Antibodies Research
- Eosinophilic Disorders and Syndromes
- Case Reports on Hematomas
- Gout, Hyperuricemia, Uric Acid
- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Inflammasome and immune disorders
- Liver Diseases and Immunity
Osh State University
2022-2025
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Системная красная волчанка (СКВ) — это аутоиммунное заболевание соединительной ткани, характеризующееся системным воспалением, которое затрагивает различные органы и ткани. Цель настоящего исследования заключалась в оценке частоты клинических проявлений поражения печени у 78 пациентов с СКВ. Для этого использовались методы клинического обследования, биохимический анализ крови (определение уровня трансаминаз, билирубина, альбумина), серологические для выявления специфических антител...
Hyperuricemia is a condition characterized by an increase of serum uric acid level above 360 µmol/L. It known that high levels are not only the for etiopathogenesis gout but also important risk factor development and progression cardiovascular diseases, kidney liver pathologies, type 2 diabetes, others. This makes hyperuricemia relevant issue in general therapeutic practice. Despite extensive evidence on negative role many internal organ management strategy patients with asymptomatic real...
The aim of present work was to evaluate clinical significance B-lymphocytes spontaneous antibody-synthesizing activity by (LASA) in patients with rheumatic inflammatory diseases (RD), i.e., reactive arthritis (ReA), ankylosing spondylitis (AS), rheumatoid (RA), and systemic lupus erythematosus (SLE). Significantly higher LASA levels were revealed the ReA, AS, RA, SLE, as compared healthy persons osteoarthrosis. Clinical indexes their changes may reflect manifestation degree immunological...
In this work examined the effect of various types basic therapy on laboratory, including immunological parameters in ankylosing spondylitis. The influence treatment patients with spondylitis sulfasalazine, methotrexate and rituximab laboratory indicators disease such as ESR, CRP, fibrinogen IgM, IgG IgA was evaluated. It has been established that all three drugs (sulfasalazine, rituximab) have a positive dynamics parameters. But at same time, more pronounced earlier effect.