A5005672263- Plant Molecular Biology Research
- Analytical chemistry methods development
- Pluripotent Stem Cells Research
- Analytical Chemistry and Chromatography
- Adipose Tissue and Metabolism
- Plant Gene Expression Analysis
- Advanced biosensing and bioanalysis techniques
- CRISPR and Genetic Engineering
- Microfluidic and Capillary Electrophoresis Applications
- Biosensors and Analytical Detection
- Animal Nutrition and Physiology
- Ginseng Biological Effects and Applications
- Plant Reproductive Biology
- Sirtuins and Resveratrol in Medicine
- Carbon and Quantum Dots Applications
- Cancer therapeutics and mechanisms
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Effects of Environmental Stressors on Livestock
- Plant biochemistry and biosynthesis
- Drug Transport and Resistance Mechanisms
- Photosynthetic Processes and Mechanisms
- Water Treatment and Disinfection
Beijing Forestry University
2018-2025
Peking University
1993-2025
Henan University of Technology
2023-2025
Southern Medical University
2013-2025
Nanfang Hospital
2013-2025
Center for Life Sciences
2024-2025
China Railway Group (China)
2025
China Railway 18th Bureau Group Corporation
2025
Yantai University
2019-2024
Tsinghua University
2024
The differentiation capacity of human embryonic stem cells (hESCs) holds great promise for therapeutic applications. We report a novel three-stage method to efficiently direct the into hepatic in serum-free medium. Human ESCs were first differentiated definitive endoderm by 3 days Activin A treatment. Next, presence fibroblast growth factor-4 and bone morphogenetic protein-2 culture medium 5 induced efficient from cells. Approximately 70% expressed marker albumin. After 10 further vitro...
The essentially infinite expansion potential and pluripotency of human embryonic stem cells (hESCs) makes them attractive for cell-based therapeutics. In contrast to mouse (mESCs), hESCs normally undergo high rates spontaneous apoptosis differentiation, making difficult maintain in culture. Here we demonstrate that p53 protein accumulates apoptotic induced by agents damage DNA. However, despite the accumulation p53, it nevertheless fails activate transcription its target genes. This...
The gastrointestinal tract is considered as one of the main target organs affected by heat stress. Phytogenic feed additives containing phenolics and flavonoids can improve resistance broilers to This study was conducted investigate effects dietary supplementation with enzymatically treated Artemisia annua (EA) on growth performance, intestinal morphology, digestive enzyme activities, immunity antioxidant capacity challenged One hundred forty-four 21-day-old male Arbor Acres were randomly...
For non-model plants, functional characterization of genes is still hampered by lack efficient stable transformation procedures. Here, we report a simple, fast and technique with Agrobacterium rhizogenes for generating transgenic roots in living plants to facilitate studies vivo. We showed that injection A. into stems various plant species lead root generation, which can sustain growth after the original, non-transgenic were cut off. A system was established pigeon pea, major woody food...
Abstract Melatonin improves plant resistance to multiple stresses by participating in the biosynthesis of metabolites. Flavonoids are an important family secondary metabolites and widely recognized be involved resistance; however, crosstalk between melatonin flavonoid is largely unknown. We found that pigeon pea (Cajanus cajan) salt, drought, heat were significantly enhanced pre-treatment with melatonin. Combined transcriptome LC-ESI-MS/MS metabolomics analyses showed induced enrichment...
SUMMARY Calcineurin B‐like (CBL)‐interacting protein kinases (CIPKs) play a central role in Ca 2+ signalling and promote drought tolerance plants. The CIPK gene family pigeon pea ( Cajanus cajan L.), major food crop affected by drought, has not previously been characterised. Here, we identified 28 genes the genome. Five CcCIPK were strongly upregulated roots upon treatment selected for further characterisation. Overexpression of CcCIPK13 CcCIPK14 increased survival rates two‐ to three‐fold...
Stimuli-responsive hydrogels are flourishing; however, a multiresponsive luminescent hydrogel actuator in which the stimuli do not interfere with each other is still difficult to produce. Here, smart bilayer shape memory and reversible luminescence switch behaviors under co-stimulation of pH heating reported. Under alkaline condition, chitosan-containing layer generates physical microcrystals fix temporary while lanthanide emits bright luminescence. Upon acid treatment, recovers its original...
Molecular imprinting-based ratiometric fluorescence (MI-RFL) nanosensors receive increasing concerns in various fields such as food security, owing to high selectivity and sensitivity, nondestruction, convenience, visualization, etc. Herein, a ternary-emission MI-RFL nanosensor was facilely constructed by postimprinting mixing (PIM) red-emission molecularly imprinted polymers (r-MIPs) green MIPs (g-MIPs) for rapid visual detection of folic acid (FA) samples. The two fluorescent were prepared...
Abstract Cold damage poses a significant challenge to the cultivation of soft-seeded pomegranate varieties, hindering growth industry. The genetic basis cold tolerance in pomegranates has remained elusive, largely due lack high-quality genome assemblies for cold-tolerant varieties and comprehensive population-scale genomic studies. In this study, we addressed these challenges by assembling chromosome-level reference 'Sanbai', variety renowned its freezing resistance, achieving an impressive...
Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits effectiveness domain-specific applications that require specialized knowledge, healthcare, chemistry, or legal analysis. To address this, researchers explored diverse methods to enhance LLMs by integrating knowledge. In this survey, we provide a comprehensive overview of these...
The derivation of hepatic progenitor cells from human embryonic stem (hES) is value both in the study early liver organogenesis and creation an unlimited source donor for hepatocyte transplantation therapy. Here, we report first time generation derived hES cells. Hepatic endoderm were generated by activating FGF BMP pathways then purified fluorescence activated cell sorting using a newly identified surface marker, N-cadherin. After co-culture with STO feeder cells, these yielded colonies,...
This study was conducted to investigate the effects of oridonin (ORI) on growth performance and antioxidant capacity in broiler chickens that were repeatedly challenged with lipopolysaccharide (LPS). A total 384 one-day-old male Arbor Acre randomly assigned 8 treatments 6 replicate cages per treatment birds replicate. There 4 dietary treatments: control group (birds fed basal diet), ORI 50 group, 80 100 (the diet supplemented 50, 80, mg/kg oridonin, respectively). Broilers intraperitoneally...