A5004659153- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Pain Mechanisms and Treatments
- MRI in cancer diagnosis
- Neuroscience and Neuropharmacology Research
- Cardiovascular and exercise physiology
- Schizophrenia research and treatment
- Advanced NMR Techniques and Applications
- Muscle activation and electromyography studies
- Cardiac Imaging and Diagnostics
- Genetic Neurodegenerative Diseases
- Musculoskeletal pain and rehabilitation
- Medical Imaging Techniques and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- NMR spectroscopy and applications
- Vascular Malformations and Hemangiomas
- Atomic and Subatomic Physics Research
- Infrared Thermography in Medicine
- Healthcare and Venom Research
- Treatment of Major Depression
- Ultrasound Imaging and Elastography
- Neurobiology of Language and Bilingualism
- Muscle metabolism and nutrition
- Sports Performance and Training
University Hospital in Halle
2020-2024
Martin Luther University Halle-Wittenberg
2023
Jena University Hospital
2010-2020
Friedrich Schiller University Jena
2008-2018
Interventional studies suggest that changes in physical fitness affect brain function and structure. We studied the influence of high intensity exercise on hippocampal volume metabolism 17 young healthy male adults during a 6-week program compared with matched controls. further aimed to relate these hypothesized exercised-induced brain-derived neurotrophic factor (BDNF), interleukin-6 (IL-6), tumor necrosis alpha (TNF-α). show profound improvement most subjects positive correlation between...
Vulnerability to infectious diseases in refugees is dependent on country of origin, flight routes, and conditions. Information specific medical needs different groups lacking. We assessed the prevalence diseases, immunity vaccine-preventable chronic conditions children, adolescents, adult from Ukraine who arrived Germany 2022. Using media, we recruited Ukrainian at 13 sites between 9-12/2022. An antigen test for acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection, serologies...
Abstract Functional reorganisation of the salience network (SN) has been proposed as one key pathomechanisms associated with central nociceptive processing in chronic pain state. Being an altered functional connectivity within SN, these processes have hypothesized to result from a loss inhibitory function leading node hyperexcitability and spontaneous pain. Combined resting-state BOLD magnetic resonance imaging (MRI) 1 H-MR spectroscopy was applied back patients healthy subjects assess...
Exercise‐induced changes of transverse proton relaxation time ( T 2 ), tissue perfusion and metabolic turnover were investigated in the lower back muscles volunteers by applying muscle functional MRI (mfMRI) diffusion‐weighted imaging (DWI) before after as well dynamic 31 P‐MRS during exercise. Inner M. multifidus , MF) outer erector spinae ES) examined 14 healthy young men performing a sustained isometric trunk‐extension. Significant phosphocreatine (PCr) depletions ranging from 30% (ES) to...
Choline (Cho) signal identification and quantification in 1 H MRS are used breast cancer diagnosis. However, an influence of the gadolinium‐based contrast agent on Cho amplitude has been reported experimentally. This study aims to identify impact agents detection postcontrast MRS. Consecutive patients were recruited prospectively randomly allocated two groups. Group A received a neutral (gadolinium diethylenetriaminepentaacetic acid bis‐methylamide) group B ionic acid) agent, each at dosage...
<sup>18</sup>F-FDG PET/MRI might be the diagnostic method of choice for Hodgkin lymphoma patients, as it combines significant metabolic information from PET with excellent soft-tissue contrast MRI and avoids radiation exposure CT. However, a major issue is longer examination times than PET/CT, especially younger children needing anesthesia. Thus, targeted selection suitable whole-body sequences important to optimize workflow. <b>Methods:</b> The initial scans 84 EuroNet-PHL-C2 study patients...
Understanding cerebellar alterations due to healthy aging provides a reference point against which pathological findings in late-onset disease, for example spinocerebellar ataxia type 6 (SCA6), can be contrasted. In the present study, we investigated impact of on nuclei and cortex 109 controls (age range: 16 - 78 years) using 3 Tesla magnetic resonance imaging (MRI). Findings were compared with 25 SCA6 patients 38 years). A subset (included: 14) 50 45) received an additional MRI scan at 7...
To assess the additional value of quantitative tCho evaluation to diagnose malignancy and lymph node metastases in suspicious lesions on multiparametric breast MRI (mpMRI, BI-RADS 4, 5).One hundred twenty-one patients that demonstrated using DCE, T2w, diffusion-weighted (DW) images were prospectively enrolled this IRB-approved study. All underwent single-voxel proton MR spectroscopy (1H-MRS, point-resolved sequence, TR 2000 ms, TE 272 ms) with without water suppression. The total choline...