A5058368615- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Sports injuries and prevention
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Cardiac pacing and defibrillation studies
- Organ Transplantation Techniques and Outcomes
- Genetic Syndromes and Imprinting
- Parathyroid Disorders and Treatments
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Liver Disease and Transplantation
- Polyomavirus and related diseases
- Congenital heart defects research
- Liver Disease Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Glycogen Storage Diseases and Myoclonus
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Beijing Anzhen Hospital
2024-2025
Shenzhen Institutes of Advanced Technology
2025
Imaging Center
2025
Capital Medical University
2025
The Eighth Hospital of Xi'an
2017
Xi'an Jiaotong University
2017
Abstract Background and Aims Identifying patients with hypertrophic cardiomyopathy (HCM) who are candidates for implantable cardioverter defibrillator (ICD) implantation in primary prevention sudden cardiac death (SCD) is crucial. The aim of this study was to externally validate the 2022 European Society Cardiology (ESC) model other guideline-based ICD class recommendation (ICD-COR) models explore utility late gadolinium enhancement (LGE) further risk stratification. Methods Seven hundred...
Abstract Background & Aims We previously found that hepatic stellate cell activation induced by autophagy maintains the liver architecture to prevent collapse during acute failure. Nitric oxide has shown induce apoptosis. Whether and how nitric is involved in failure remains unclear. Methods Acute patients were recruited investigate correlation between plasma levels clinical features. Liver tissues collected from chronic hepatitis biopsy who had undergone transplantation. The expression...
In hypertrophic cardiomyopathy, myocardial microstructural alterations could be detected by in vivo cardiac diffusion-tensor imaging even before the appearance of MRI findings hypertrophy or fibrosis.
Abstract Aims This study aims to demonstrate the characteristics of late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance (CMR) imaging in patients with giant cell myocarditis (GCM). Methods and results Six histologically diagnosed GCM were retrospectively recruited this study. All them underwent CMR during hospitalization. The distribution extent LGE on both ventricles, AHA‐17 segment model was used for left ventricular (LV) analysis. Nine case reports reviewed...
Assessing the structure and function of left atrium (LA) is crucial in hypertrophic obstructive cardiomyopathy (HOCM) because LA remodeling correlates with atrial fibrillation. However, few studies have investigated potential effect myomectomy on phasic HOCM after myectomy using cardiovascular magnetic resonance (CMR) feature tracking (FT). This study aims to evaluate structural functional by CMR-FT further investigate determinants reverse remodeling. In this single-center study, we...
Abstract Aims This study aimed to evaluate the association between cardiac MRI (CMR) multiparameters and significant acute allograft rejection (SR), assess incremental value of CMR over conventional serum examinations for identifying SR. Methods results Heart transplantation (HTx) recipients with endomyocardial biopsy healthy controls were prospectively recruited assessment. feature tracking (CMR-FT) was performed left ventricular (LV) global strain in all three directions. The last...
Background Sarcomere gene mutation and myocardial fibrosis are both associated with poorer clinical outcomes in patients hypertrophic cardiomyopathy (HCM). The aim of this study was to determine the relationship between sarcomere measured by histopathology cardiac magnetic resonance (CMR). Methods Results Two hundred twenty-seven HCM who underwent surgical treatment, genetic testing, CMR were enrolled. We retrospectively analyzed basic characteristics, mutation, histopathology. In our study,...
This study aims to validate and compare the feasibility of T1ρ native longitudinal relaxation time (T1) mapping in detection myocardial fibrosis patients with non-ischaemic cardiomyopathy, focusing on performance both methods identifying late gadolinium enhancement (LGE) grey zone.Twenty-seven hypertrophic cardiomyopathy (HCM) patients, 16 idiopathic dilated (DCM) 18 healthy controls were prospectively enrolled for T1 imaging then all underwent scan LGE extent extracellular volume (ECV)...
Strain analysis is a sensitive method for the assessment of ventricular structural or functional alterations. The authors aimed to determine whether right (RV) strain parameters can discriminate patients with revised Task Force Criteria-diagnosed arrhythmogenic RV cardiomyopathy (ARVC) incremental existing cardiovascular magnetic resonance (CMR) criteria, thus improving diagnostic yield CMR in ARVC.
Abstract Objectives This study aimed to evaluate the prognostic value of left atrial (LA) strain in patients with apical hypertrophic cardiomyopathy (ApHCM), as assessed by cardiac magnetic resonance (CMR) imaging. Methods Four hundred and five consecutive ApHCM who underwent CMR examination were retrospectively included. The endpoint included all-cause death, heart transplant, aborted sudden hospitalization for failure, stroke, new-onset fibrillation (AF). Results After a median follow-up...
To investigate myocardial remodeling using cardiac MRI (CMR) feature tracking (FT) and to explore the relationship between CMR parameters with outcomes in hypertrophic obstructive cardiomyopathy (HOCM) after myectomy.In this single-center retrospective study, patients HOCM undergoing myectomy 2011 2019 were included. Pre- postmyectomy global regional strains compared. Healthy participants included for comparison. Composite events recorded at follow-up performed a minimum of 12 months. The...
Despite the use of cardiovascular magnetic resonance (CMR) feature tracking (FT) imaging to detect myocardial deformation, optimal strain index in dilated cardiomyopathy (DCM) is unclear. This study aimed determine whether atrial and biventricular strains can provide greatest or joint incremental prognostic value patients with DCM over a long follow-up period. Four hundred-twelve were included retrospectively. Comprehensive clinical evaluation investigations obtained, including measurements...