Xiuyu Chen

ORCID: 0000-0002-0851-9574
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About
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Research Areas
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Advanced MRI Techniques and Applications
  • Cardiovascular Effects of Exercise
  • HVDC Systems and Fault Protection
  • High-Voltage Power Transmission Systems
  • Cardiac Structural Anomalies and Repair
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Viral Infections and Immunology Research
  • Cardiovascular Disease and Adiposity
  • Congenital Heart Disease Studies
  • Sports injuries and prevention
  • Cardiac Valve Diseases and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Advanced Photocatalysis Techniques
  • Aortic Disease and Treatment Approaches
  • Microgrid Control and Optimization
  • Mesenchymal stem cell research
  • Thermal Radiation and Cooling Technologies
  • Cardiac Arrest and Resuscitation
  • Atrial Fibrillation Management and Outcomes
  • Coronary Artery Anomalies
  • Electrospun Nanofibers in Biomedical Applications

Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025

Yangzhou University
2023-2025

Imaging Center
2025

Shenzhen Institutes of Advanced Technology
2025

Henan Normal University
2023-2025

Nanjing Medical University
2022-2025

Jiangsu Cancer Hospital
2025

Guangzhou Institutes of Biomedicine and Health
2024-2025

Jimei University
2022-2024

Chinese University of Hong Kong
2022-2024

Cardiac magnetic resonance imaging (CMR) is the gold standard for cardiac function assessment and plays a crucial role in diagnosing cardiovascular disease (CVD). However, its widespread application has been limited by heavy resource burden of CMR interpretation. Here, to address this challenge, we developed validated computerized interpretation screening diagnosis 11 types CVD 9,719 patients. We propose two-stage paradigm consisting noninvasive cine-based followed cine late gadolinium...

10.1038/s41591-024-02971-2 article EN cc-by Nature Medicine 2024-05-01

Abstract: The carbonyl stress that leads to the formation of advanced glycation end products (AGEs) has drawn much attention recently because its micro‐ and macrovascular implications. During monitoring methylglyoxal (MG), efficiency phenolics directly trap MG can be demonstrated. Twenty compounds consisting a single benzene ring structure with addition at least one hydroxyl group were allowed react 37 °C for 1 h under physiological conditions in pH 7.4 phosphate buffer solution. Compounds...

10.1111/j.1750-3841.2011.02067.x article EN Journal of Food Science 2011-03-16

Abstract Aims Hypertrophic cardiomyopathy (HCM) with left ventricular apical aneurysm (LVAA) is associated an increased risk of adverse cardiovascular events. However, the clinical significance LVAA in HCM (ApHCM) has not been reported. This study aimed to investigate prevalence, cardiac magnetic resonance (CMR) characteristics, and prognosis ApHCM patients. Methods results A total 1332 consecutive patients confirmed by CMR our hospital were retrospectively analysed. LVAAs identified 31 all...

10.1093/ehjci/jeaa246 article EN European Heart Journal - Cardiovascular Imaging 2020-08-08

Summary Horse oil contains linoleic, palmitoleic and unsaturated fatty acids that are similar to those in human skin, may therefore be an ideal substance from which isolate biosurfactants for cosmetic products improve skin quality. Herein, innovative approach was developed synthesise sophorolipids horse by hydrolysis, followed fermentation using the yeast Candida bombicola . The yield of direct hydrolysed 40.6 ± 1.3 g l −1 58.4 1.8 respectively. To further increase yield, 30–40 glucose added...

10.1111/1751-7915.13297 article EN cc-by Microbial Biotechnology 2018-07-18

Salt stress affects the growth and development of plants, which results in a decrease crop quality yield. In this study, we used tomato seedlings treated with salt trehalose as experimental materials analyzed them using technique for order preference by similarity to ideal solution analysis select optimal concentration treatment. We also determined contents sugar abscisic acid (ABA) detected expression genes involved metabolism ABA quantitative real-time PCR. Results showed that was 2 mmol/L...

10.1007/s12209-019-00214-x article EN cc-by Transactions of Tianjin University 2019-07-03

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a hereditary heart disease characterized by fatty infiltration, life-threatening arrhythmias, and increased risk of sudden cardiac death. The guideline for management ARVC in patients to improve quality life reducing arrhythmic symptoms prevent However, the mechanism underlying ARVC-associated arrhythmias remains poorly understood.Using protein mass spectrometry analyses, we identified that integrin β1 downregulated hearts without...

10.1161/circulationaha.119.043504 article EN Circulation 2020-03-18

Abstract MRI for in vivo stem cell tracking remains controversial. Here we tested the hypothesis that can track long-term fate of superparamagnetic iron oxide (SPIO) nanoparticles labelled mesenchymal cells (MSCs) following intramyocardially injection AMI rats. MSCs (1 × 10 6 ) from male rats doubly labeled with SPIO and DAPI were injected 2 weeks after myocardial infarction. The control group received cell-free media injection. In serial was performed at 24 hours before delivery (baseline),...

10.1038/srep09058 article EN cc-by Scientific Reports 2015-03-12

An efficient protocol for the synthesis of polyfunctionalized tetrahydrocyclopenta[4,5]pyrrolo[2,3- b ]pyridine-3,4b,5,6,7(1 H )-pentacarboxylates was developed by a three-component reaction. In absence any catalyst, reaction alkyl isocyanides, dialkyl but-2-ynedioates and 5,6-unsubstituted 1,4-dihydropyridines in refluxing acetonitrile afforded high yields with diastereoselectivity. The finished situ generation activated 5-(alkylimino)cyclopenta-1,3-dienes from addition isocyanide to two...

10.3762/bjoc.20.126 article EN cc-by Beilstein Journal of Organic Chemistry 2024-06-28

This paper investigates interconverter interactions in multi-infeed systems that include both rectifiers and inverters. Performance indices used earlier for multi-inverter are extended to the rectifier-inverter mix. These can be predict maximum available power (MAP) stability limits of converters as well transient phenomena, such overvoltages (TOV) inverter commutation failures (CF ).The results show presence a rectifier neighborhood inverters is effectively similar an increase inverters'...

10.1109/tpwrd.2012.2187356 article EN IEEE Transactions on Power Delivery 2012-03-22

Objectives: To investigate the correlation of cardiac magnetic resonance (CMR) feature-tracking with conventional CMR parameters in patients a first anterior ST-segment elevation myocardial infarction (STEMI). Methods: This sub-analysis OCTAMI (Optical Coherence Tomography Examination Acute Myocardial Infarction) registry included 129 who finished examination 1 month after STEMI. Cine images were applied to calculate both global and segmental left ventricular peak strain parameters. The...

10.3389/fcvm.2021.705487 article EN cc-by Frontiers in Cardiovascular Medicine 2021-07-02

In hypertrophic cardiomyopathy, myocardial microstructural alterations could be detected by in vivo cardiac diffusion-tensor imaging even before the appearance of MRI findings hypertrophy or fibrosis.

10.1148/ryct.240009 article EN Radiology Cardiothoracic Imaging 2025-01-02

Here, we revealed a convenient synthetic protocol for unique pyrido[2,3-c]pyridazine and pyrido[3,2-e][1,2]oxazine scaffolds with excellent regioselectvity diastereoselectivity. The functionalized pyrido[2,3-c] pyridazines were successfully synthesized via Cs2CO3-promoted [4 + 2] cycloaddition reaction of α-halogenated N-tosylhydrazones or N-acylhydrazones 5,6-unsubstituted 1,4-dihydropyridines under mild conditions. Additionally, the similar base-promoted α-chlorogenated oximes afforded...

10.1021/acs.joc.4c02525 article EN The Journal of Organic Chemistry 2025-02-14

Infrared (IR) camouflage has garnered growing attention with progress in IR detection technology. The emergence of metamaterial powerful electromagnetic field regulation ability provides an effective solution for thermal emission manipulation camouflage. However, the intricated micro/nano machining technology greatly limits its moving toward practical application, and single-band makes it difficult to resist multiband cooperative systems. Here, a flexible, fine, mask-free femtosecond laser...

10.1515/nanoph-2024-0763 article EN cc-by Nanophotonics 2025-03-17
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