A5100370059- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Cancer therapeutics and mechanisms
- Catalytic C–H Functionalization Methods
- Synthesis and bioactivity of alkaloids
- Synthesis and Biological Evaluation
- Titanium Alloys Microstructure and Properties
- Analytical chemistry methods development
- Cyclopropane Reaction Mechanisms
- Synthesis and Catalytic Reactions
- Surface Modification and Superhydrophobicity
- 2D Materials and Applications
- Metallurgy and Material Forming
- melanin and skin pigmentation
- Berberine and alkaloids research
- Metal and Thin Film Mechanics
- Asymmetric Synthesis and Catalysis
- Luminescence and Fluorescent Materials
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Sulfur-Based Synthesis Techniques
- Asymmetric Hydrogenation and Catalysis
- Microstructure and mechanical properties
- Nanoplatforms for cancer theranostics
- Semiconductor materials and devices
Guangxi Medical University
2019-2025
Stomatology Hospital
2025
Huizhou Central People's Hospital
2025
Xuzhou Medical College
2025
Guizhou University
2016-2025
University of Jinan
2014-2024
Northwest Normal University
2024
Sun Yat-sen University
2008-2024
Chongqing University
2023-2024
Chengdu Medical College
2024
Understanding the complex functions of plant leaves requires a thorough characterization discrete cell features. Although single-cell gene expression profiling technologies have been developed, their application in characterizing subtypes has not achieved yet. Here, we present scStereo-seq (single-cell spatial enhanced resolution omics sequencing) that enabled us to show bona fide transcriptome profiles Arabidopsis leaves. Subtle but significant transcriptomic differences between upper and...
A novel stimuli-responsive protein imprinted polymer for selective recognition of bovine serum albumin is presented. N-[3-(Dimethylamino)propyl]-methacrylamide, which positively charged in neutral solution and able to self-assemble onto the template through electrostatic interaction, was chosen as functional monomer. Polymerization carried out presence N-isopropylacrylamide an assistant monomer, resulted a polymer. The proteins were easily removed by treatment with 500 mmol L(-1) NaCl...
Water-soluble hydrogel nanoparticles have been synthesized by the incorporation of stimuli-sensitive monomer N-isopropylacrylamide (NIPAM) to a catalytic, molecularly imprinted system. The unique properties pNIPAM copolymerized with cationic and anionic polymers offers homogenously biocompatible catalytic system switchable response pH change. maximum efficiency can thus be significantly increased.
Abstract Covalent organic frameworks (COFs) have emerged as potential light emitting polymers for optoelectronic and optical devices, but their nonlinear properties, particularly two‐photon absorption fluorescence (TPA/TPF), seldom been explored. Herein, to construct octupolar three‐branched modules (e.g., acceptor 3‐(donor‐core), triphenylbenzene core) within a 2D cyano‐sp 2 c‐conjugated framework is proposed that results in luminescent COFs, combining large TPA cross section high quantum...
Carbamylated erythropoietin (CEPO), a well characterized (EPO) derivative, does not bind to the classical EPO receptor and stimulate erythropoiesis. Using neural progenitor cells derived from subventricular zone of adult mouse, we investigated effect CEPO on neurogenesis associated signaling pathways in vitro. We found that significantly increased cell proliferation promoted differentiation into neurons, which was with up-regulation Sonic hedgehog (Shh), its ptc, mammalian achaete-scute...
The nanocrystal-in-glass (nanocrystals embedded amorphous matrix) tungsten oxide (WO3) thin films with a nanoporous characteristic were prepared via an electron beam evaporation technique. e-beam evaporated WO3 present fast colored/bleached time of 16/11, 16/14, and 12/12 s, large optical modulation 92, 91, 87% at 633 nm, high coloration efficiency 61.78, 62.04, 67.59 cm2 C–1 in Li+, Na+, Al3+ electrolytes, respectively. On one hand, the improved electrochromic performance is mainly...
Abstract Stimuli‐responsive protein imprinted polymers were obtained via a combination of molecular imprinting and reversible stimuli‐responsive polymer using lysozyme or cytochrome c as template, N ‐isopropylacrylamide (NIPA) major monomer, methacrylic acid (MAA) acrylamide (AAm) functional co‐monomers, , ‐methylenebisacrylamide (MBAAm) crosslinker. The molecularly (MIPs) can respond not only to external stimuli such temperature salt concentration, but also the corresponding template with...
Cancer cells possess some inherent characteristics, such as glucose-dependence and intolerance to heat exogenous reactive oxygen species (ROS). In this study, a strategy has been developed target these vulnerable weaknesses of cancer using glucose oxidase (GOx) polydopamine (PDA) functionalized iron oxide nanoparticles (Fe3O4@PDA/GOx NPs). PDA is first deposited on the surfaces NPs through self-polymerization, then GOx covalently linked with upon mixing enzyme Fe3O4@PDA under alkaline...
Background: Sulforaphane (SFN), an isothiocyanate naturally occurring in cruciferous vegetables, is a potent indirect antioxidant and promising agent for the control of metabolic disorder disease. The glucose intolerance adipogenesis induced by diet rats was inhibited SFN. Strategies aimed at induction brown adipose tissue (BAT) could be potentially useful way to against obesity. However, vivo protective effect SFN obesity browning white adipocyte has not been reported. Our present study...
The bound states in the continuum (BICs) optical metasurfaces have latterly received prominent attention for their ultrahigh quality factors and promise that they hold realizing lowthreshold nanolasers, high-harmonic generation, slow-light devices. In this scenario, flexible tuning of BIC is at heart multifunctional tunable metadevices underpinning central role modulation spectral responses. Most BIC-inspired works are limited to single types BICs modes only affected by structural...
Neutral sphingomyelinase 1 (NSMase1) mediates caspase-3 activation and apoptosis. However, the role of NSMase1, especially exosome-borne NSMase1 in hepatocellular carcinoma (HCC), remains unclear. We report that which converts sphingomyelin (SM) to ceramide, was significantly downregulated HCC tissues. Low expression predicted poor long-term survival patients. downregulation resulted increased SM reduced ceramide (Cer) led an SM/Cer ratio. Interestingly, NSMase activity were also decreased...
Abstract Alpha lipoic acid (ALA) is a powerful antioxidant which has been widely used in the treatment of different system diseases, such as cardiovascular and cerebrovascular diseases. But, there are few studies that refer to protective effects potential mechanisms on traumatic brain injury (TBI). This study was carried out investigate neuroprotective effect following TBI illuminate underlying mechanism. Weight drop‐injured model rats induced by weight‐drop. ALA administrated via...
Famoxadone-cymoxanil is a new protective and therapeutic fungicide, but little research has been done on it or its toxicity in aquatic organisms. In this study, we used zebrafish to investigate the cardiotoxicity of famoxadone-cymoxanil potential mechanisms involved. Zebrafish embryos were exposed different concentrations until 72 h post-fertilization (hpf), then changes heart morphology observed. We also detected levels oxidative stress, myocardial-cell proliferation apoptosis, ATPase...
A mild and eco-friendly visible-light-induced protocol for the hydroacylation of quinones with α-keto acids has been developed. In absence any catalyst or additive, decarboxylative proceeded smoothly under visible-light irradiation at room temperature. wide range were well-tolerated afforded products up to 88% isolated yield. The reaction can be scaled up, induced groups are useful further synthetic applications. Preliminarily, mechanistic studies indicated that photoactive absorb visible...
By elucidating the progressive relationship from rolling stress state to activation of slip systems and then lattice rotation, this paper clarifies influence mechanism strain paths on evolution α-phase texture in near-α titanium alloys. The distinct textures obtained further provide a robust foundation for investigating whether competition between different changes with varying cooling rates during β→α phase transformation. In study, initial Ti65 alloy sheets underwent using three...