A5045264716- Semiconductor Quantum Structures and Devices
- GaN-based semiconductor devices and materials
- Boron Compounds in Chemistry
- Superconducting and THz Device Technology
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Ga2O3 and related materials
- Toxoplasma gondii Research Studies
- Brain Metastases and Treatment
- Nuclear Physics and Applications
- Semiconductor materials and devices
- Silicon Carbide Semiconductor Technologies
- Semiconductor materials and interfaces
- MicroRNA in disease regulation
- Terahertz technology and applications
- Radio Frequency Integrated Circuit Design
- Radiation Therapy and Dosimetry
- Colorectal and Anal Carcinomas
- Lung Cancer Research Studies
- Herpesvirus Infections and Treatments
- Parasitic Infections and Diagnostics
- Gastric Cancer Management and Outcomes
- Cytomegalovirus and herpesvirus research
- Radiomics and Machine Learning in Medical Imaging
Fudan University
2020-2025
Windsor Regional Hospital
2014-2025
Shanghai Traditional Chinese Medicine Hospital
2025
University of Windsor
2021-2024
South China Agricultural University
2024
Sun Yat-sen University
2023-2024
Hubei University of Medicine
2024
Taihe Hospital
2024
Huazhong Agricultural University
2016-2023
Western University
2016-2023
Textbook-like device characteristics are demonstrated in vertical GaN p-n diodes grown on bulk substrates. These devices show simultaneously an avalanche breakdown voltage (BV) of >1.4 kV under reverse bias, ideality factor plateau ∼2.0 a forward bias window followed by near unity 1.1, which consistently achieved over temperature range 300–400 K. At room (RT), the diode with mesa diameter 107 μm showed differential on-resistance Ron 0.12 mΩcm2, thus resulting record figure-of-merit...
This work demonstrates the high-frequency and high-power performance capacity of GaN high electron mobility transistors (HEMTs) on Si substrates. Using a T-gate <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${n}^{++}$ </tex-math></inline-formula> -GaN source/drain contacts, InAlN/GaN HEMT with gate length 55 nm source-drain spacing 175 shows maximum drain current notation="LaTeX">${I}_{{D,MAX}}$ 2.8 A/mm...
We present the design principle and experimental demonstrations of GaN trench junction-barrier-Schottky-diodes(trench JBSDs), where Schottky contact within patterned trenches is at same plane as adjacent p-n junctions. Assisted by TCAD simulations, leakage current reduction mechanism identified reduced surface field (RESURF) effect due to barrier-height difference between junction junction. Design space for width stripe-shaped found be <;0.5 μm a drift layer doping level 10 <sup...
Cell-free DNA (cfDNA), a burgeoning class of molecular biomarkers, has been extensively studied across variety biomedical fields. As key component liquid biopsy, cfDNA testing is gaining prominence in disease detection and management due to the convenience sample collection abundant wealth genetic information it provides. However, broader clinical application currently impeded by lack standardization preanalytical procedures for analysis. A number fundamental challenges, including selection...
A high combination of three-terminal breakdown voltage (VBK) and current gain cutoff frequency (f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> ) was achieved with SiN xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> /InAlN/AlN/GaN metal-insulator- semiconductor high-electron mobility transistors (MIS-HEMTs). 1-nm gate dielectric deposited ex situ in a molecular beam epitaxy system used to increase the carrier density 2-D electron...
The gain and photoresponse characteristics have been numerically studied for back-illuminated separate absorption multiplication (SAM) GaN avalanche photodiodes (APDs). parameters of fundamental models are calibrated by simultaneously comparing the simulated dark light current with experimental results. Effects environmental temperatures device dimensions on investigated, a method to achieve optimum thickness charge layer is obtained. dependence breakdown voltage doping concentration also in...
Background: In China, gastric cancer (GC) ranks second in incidence and mortality. Over 80% of patients with GC were diagnosed at an advanced stage poor clinical outcome. Chemotherapy was the mainstream treatment limited benefit. Apatinib, inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR2), has been approved for third-line cancer. However, data apatinib real-world setting are limited. this study, we aimed to understand current pattern apatinib, investigate...
Each year more than 3000 Canadians are diagnosed with brain cancers like glioblastoma multiforme or recurrent head and neck cancers, which difficult to treat conventional radiotherapy techniques. One of the most clinically promising treatments for these is boron neutron capture therapy (BNCT). This procedure involves selectively introducing a delivery agent into tumor cells irradiating them beam, kills cancer due high-linear energy transfer radiation produced by 10 B(n,α) 7 Li reaction. The...
Abstract Toxoplasma gondii ( T. ) is an obligate intracellular parasite with a wide range of hosts, including humans and many warm-blooded animals. The exists in two interconvertible forms, namely tachyzoites bradyzoites intermediate hosts that are responsible for acute chronic infections respectively. Mature accumulate large amounts amylopectin granules but their roles have not been fully characterized. In this study, the predicted key enzymes involved synthesis (UDP-sugar...
Avian leukosis virus Subgroup J (ALV-J) exhibits high morbidity and pathogenicity, affecting approximately 20% of poultry farms. It induces neoplastic diseases immunosuppression. Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), a pro-apoptotic mitochondrial in the B-cell lymphoma-2 (Bcl-2) family, plays role apoptosis cancer cells. However, connection between PMAIP1 gene ALV-J pathogenicity remains unexplored. This study investigates potential impact on replication its regulatory...
ABSTRACT Chronic atrophic gastritis (CAG) is a precancerous lesion characterised by gastric mucosal atrophy and inflammation. Identifying key molecular mechanisms potential therapeutic targets essential to improve patient outcomes. Key modules differentially expressed genes (DEGs) were recognised in the GSE153224 dataset using weighted gene co‐expression network analysis (WGCNA) examination of differential expression. IGFBP7 was identified as hub protein–protein interaction (PPI) expression...
Toxoplasma gondii is an opportunistic pathogen infecting humans and a variety of vertebrate animals. Secretory dense-granule proteins (GRAs) play diverse roles in the mediation host-parasite interactions facilitate parasitism, but many them still remain to be identified. Here, we used two proximity-based protein labeling techniques identify novel GRA proteins. Taking GRA1 as bait, transgenic strains expressing GRA1-BirA* or GRA1-APEX were constructed biotinylate GRAs. Using these methods,...
Lateral GaN transistors on Si substrates operating at voltage below 650 V are commercially available today. The main drawback of this lateral geometry is that the transistor area (and, therefore, its cost) proportional to breakdown voltage. In addition, numerous material interfaces exposed high electric fields, which reduces reliability and prevents avalanche breakdown. For higher-voltage high-current applications, lateral-device size increases dramatically, very current levels difficult...
// Bang Shen 1 , Yuan Jianxi Cheng Ming Pan Ningbo Xia Weichao Zhang Yifan Wang Yanqin Zhou Junlong Zhao 1, 2 State Key Laboratory of Agricultural Microbiology, College Veterinary Medicine, Huazhong University, Wuhan 430070, Hubei, PR China Hubei Cooperative Innovation Center for Sustainable Pig Production, Correspondence to: Zhao, email: zhaojunlong@mail.hzau.edu.cn Keywords: Toxoplasma gondii, chronic infection, bradyzoite, reactivation, transportation stress Received: September 28, 2016...
Abstract Background Norovirus is highly diverse and constant surveillance essential for the prevention control of norovirus gastroenteritis. Methods From 2015 to 2019, fecal samples were collected from sporadic cases outbreaks acute gastroenteritis reported Sichuan center disease prevention. Sewage a wastewater treatment plant in Sichuan. All tested by real-time reverse transcription polymerase chain reaction. Norovirus-positive clinical sequenced Sanger sequencing. amplicon virome Results A...